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Models for physical AI tasks, such as robotics and autonomous driving, need not reason solely in language. They can use visual plans--points, bounding boxes, and trajectories--to represent spatial goals and anticipate motion. However, autoregressive vision-language models generate these plans one coordinate token at a time, making richer predictions increasingly costly. We introduce VFlash, a method for fast, accurate visual planning through Flash Primitive Decoding. VFlash exploits the known structure of visual primitives to predict their coordinates jointly, using a lightweight drafter that generates an entire primitive in one forward pass. The layout adapts to the primitive's type, dimensionality, and length, supporting compact boxes and long, variable-length trajectories. Crucially, spatial accuracy need not require reproducing an autoregressive model's exact token sequence. VFlash therefore trains on annotated primitives and directly accepts structurally valid predictions without target-token agreement. Across the evaluated 2D and 3D robot trajectory tasks, VFlash consistently reduces prediction errors relative to autoregressive decoding. Preliminary single-rollout measurements indicate approximately 25x faster generation for 3D point motion forecasting. A world action model conditioned on VFlash plans achieves 70.2% average success across four MolmoSpaces task suites, compared with 62.6% for the baseline.

Dynamic flexible assembly flow shop scheduling with multi-product delivery, often with kitting supply and machine-level flexibility, can be found in many applications. It is difficult to design rules manually for it. Genetic programming (GP) has been used to automatically generate dispatching rules, enabling responsive scheduling while meeting high responsiveness demands. However, GP methods are dependent on fixed terminal sets and have poor interpretability. In this work, we develop an evolving dispatching rules framework (EvoDR) that leverages the semantic understanding and generation capabilities of large language models to achieve cross-domain integration of rule design and scheduling knowledge. In our proposed framework, multi-stage assembly supply decisions are modeled as priority sorting of directed edges based on heterogeneous graphs. A dual-expert co-evolution mechanism is proposed, which allows LLM-A to generate code and LLM-S conduct scheduling analysis and reflection. Guided by improvements in hybrid evaluation, adaptive rules that fit dynamic features are continuously evolved. Experimental results show that EvoDR can achieve lower average tardiness than other automatically designed state-of-the-art approaches. It also outperforms expert-designed competitors across 480 instances over 24 distinct scenarios with varying resource configurations and disturbance levels, and EvoDR demonstrates robust adaptability across diverse operating conditions.

Self-Driving Chemical Laboratories (SDCLs) are moving chemical experimentation toward embodied automation, where machines must perceive laboratory scenes, reason about experimental states, and act under physical, procedural, and safety constraints. Although Multimodal Large Language Models (MLLMs) are increasingly considered as embodied brains for such systems, existing laboratory benchmarks mainly focus on safety, anomaly detection, or general scientific understanding, leaving their execution-oriented embodied capabilities underexplored. To fill this gap, we introduce BEAKER, a Benchmark for evaluating Embodied Actionability, Knowledge, Experimentation, and Reasoning in SDCLs. BEAKER contains 1,000 expert-curated question-answer samples across 11 image and video task types, covering key judgments required for chemical laboratory execution, including affordance grounding, trajectory planning, equipment, state, and safety recognition, apparatus setup, operation and step reasoning, and temporal procedure reasoning. All questions and annotations are manually created and reviewed by chemistry and embodied Artificial Intelligence (AI) experts, without AI-assisted generation or annotation. We evaluate 28 general-purpose, science-oriented, chemistry-specialized, and embodied MLLMs in an offline, single-turn setting. Results show that current models can follow coarse experimental procedures in videos, but still struggle to ground actions into operable regions and feasible trajectories, to recognize fine-grained laboratory apparatus, states, and safety norms, and to order steps in mid-length procedures. BEAKER thus reveals a clear gap between coarse procedural understanding and the precise, action-grounded perception required for laboratory execution, providing a diagnostic benchmark for future MLLMs in SDCLs.

In recent years, generative artificial intelligence (GenAI) has demonstrated remarkable capabilities in high-stakes domains such as molecular science. However, challenges related to the verifiability and structural privacy of its outputs remain largely unresolved. This paper focuses on the task of molecular toxicity repair. It proposes a structure-private verification framework - ToxiEval-ZKP - which, for the first time, introduces zero-knowledge proof (ZKP) mechanisms into the evaluation process of this task. The system enables model developers to demonstrate to external verifiers that the generated molecules meet multidimensional toxicity repair criteria, without revealing the molecular structures themselves. To this end, we design a general-purpose circuit compatible with both classification and regression tasks, incorporating evaluation logic, Poseidon-based commitment hashing, and a nullifier-based replay prevention mechanism to build a complete end-to-end ZK verification system. Experimental results demonstrate that ToxiEval-ZKP facilitates adequate validation under complete structural invisibility, offering strong circuit efficiency, security, and adaptability, thereby opening up a novel paradigm for trustworthy evaluation in generative scientific tasks.

Toxicity remains a leading cause of early-stage drug development failure. Despite advances in molecular design and property prediction, the task of molecular toxicity repair, generating structurally valid molecular alternatives with reduced toxicity, has not yet been systematically defined or benchmarked. To fill this gap, we introduce ToxiMol, the first benchmark task for general-purpose Multimodal Large Language Models (MLLMs) focused on molecular toxicity repair. We construct a standardized dataset covering 11 primary tasks and 660 representative toxic molecules spanning diverse mechanisms and granularities. We design a prompt annotation pipeline with mechanism-aware and task-adaptive capabilities, informed by expert toxicological knowledge. In parallel, we propose an automated evaluation framework, ToxiEval, which integrates toxicity endpoint prediction, synthetic accessibility, drug-likeness, and structural similarity into a high-throughput evaluation chain for repair success. We systematically assess 43 mainstream general-purpose MLLMs and conduct multiple ablation studies to analyze key issues, including evaluation metrics, candidate diversity, and failure attribution. Experimental results show that although current MLLMs still face significant challenges on this task, they begin to demonstrate promising capabilities in toxicity understanding, semantic constraint adherence, and structure-aware editing.