Deep learning methods for pathology are constrained by the limited availability and high cost of large-scale pixel-level annotations. Synthetic data can alleviate this limitation, but existing pipelines often lack reliable quality control and remain weakly connected to downstream analysis. To address these issues, we propose a three-stage framework that integrates automated data screening, generative representation learning, and efficient adaptation to downstream tasks. First, we develop a pathology agent system to assess image quality and filter samples, resulting in TCGA-200K, a dataset containing 217,030 pathology patches selected from the public TCGA repository. Second, we train a generative model on the screened data. In addition to image synthesis, its backbone learns structural and semantic representations that can be transferred to downstream tasks. Third, we adapt the pretrained generative backbone to semantic segmentation using a lightweight task-specific head. We further introduce PathSeg-380K, a semantic segmentation dataset with expert annotations for approximately 380,000 cells across 12 cell types. Experiments on multiple pathology datasets show that the proposed framework achieves state-of-the-art segmentation performance. Our code is publicly available at https://github.com/script-Yang/Agent-GenPath.
Shihao Hou, Chikai Shang, Jiacheng Yang, Xinyi Shang, Shreyank N. Gowda, Yan Yan, Yang Lu
Effectively addressing the joint effects of non-IID data and long-tailed distribution remains a key challenge in federated learning. While fine-tuning vision-language models (VLMs) like CLIP has shown promise in tackling non-IID scenarios, it often degrades tail-class performance when both heterogeneity and long-tailed distributions are present, even leading to overall performance falling below the zero-shot baseline. To overcome this, we propose Class-Aware Prompt Tuning (CAPT), a novel framework leveraging pre-trained VLMs to effectively learn from non-IID and long-tailed data. Specifically, CAPT introduces a dual-prompt mechanism that synergizes class-aware and general prompts, enabling the model to preserve class-specific information while capturing global trends. Furthermore, to guide the prompts in learning targeted knowledge, we propose a heterogeneity-aware clustering strategy with two key components: similarity-based clusters aggregate class-aware prompts to reinforce tail-specific knowledge, while heterogeneity-based clusters aggregate general prompts to balance diverse representations and promote robust generalization. Extensive experiments demonstrate that CAPT significantly outperforms state-of-the-art methods, e.g., by improving overall accuracy by 6.1% on ImageNet-LT and 8.8% on Places-LT over baselines, while also substantially enhancing tail-class performance across other benchmarks.
Multimodal large language models (MLLMs) hold immense potential to revolutionize clinical practice, yet deploying them in the medical domain is fundamentally a vision-centric challenge: models must absorb knowledge from heterogeneous 2D and 3D medical images, and evaluation protocols must align with radiologists' clinical practice and provide an accurate, fine-grained and factualness-driven assessment. In this paper, we introduce ClinFusion, a vision-centric MLLM designed for holistic medical understanding that systematically addresses these limitations. We propose a compositional and cascaded vision encoder architecture featuring a Cascade Spatial-Aware Locality Fusion operator that unifies diverse 2D and native 3D medical image understanding within a fused encoder. We further introduce a vision-grounded evaluation framework, including MedIF-Bench for instruction-following assessment and a region-of-interest-grounded method for clinically aligned and factualness-driven report generation evaluation. We show that ClinFusion sets a new state-of-the-art across a comprehensive suite of 2D and 3D multimodal medical benchmarks---spanning visual question answering, report generation, and instruction following---as well as textual medical tasks, outperforming leading open-source medical MLLMs (\textit{e.g.}, Hulu-Med, Lingshu) on 20 out of 24 benchmarks and demonstrating multimodal capabilities better than powerful proprietary models such as GPT-5.2 and Gemini-3-Flash on 13 out of 16 benchmarks, and can be further augmented with agentic tool use for retrieval-augmented and tool-assisted clinical workflows. A blinded evaluation by board-certified radiologists confirms that ClinFusion produces the highest-ranked reports, and validates our RoI-grounded metric as achieving the strongest correlation with expert judgment among all automatic evaluation metrics examined.
Compositional motion transfer requires a model to extract motions from multiple reference videos, and apply each motion to a user-specified object in one target scene. Existing methods normally struggle to reliably assign different reference motions to the correct target objects, thus a motion intended for one object may affect another. Meanwhile, some motion-specific tuning approaches are still facing another issue: they must run a new optimization whenever the reference video changes, making repeated transfers inefficient. To address these limitations, we propose RART, a framework that unifies object-wise motion extraction, target-region anchoring, and frame-aligned injection into a frozen video Diffusion Transformer for multi-object motion transfer. For each reference motion, RART extracts temporally ordered features from the masked reference video, and then conditions them on the target first-frame mask to form mask-anchored motion tokens. Frame-aligned motion cross-attention allows each generated frame to read only the motion tokens at the corresponding time slots, composing all object motions in one denoising process. During training, a motion-attention routing loss encourages each target region to attend to its corresponding motion tokens and reduces interference between objects. Therefore, RART can handle novel reference-target combinations without per-video optimization. Experiments show that RART achieves accurate motion preservation, efficient inference, and strong compositional generalization.
Shuolin Xu, Guanyuan Li, Boyu Li, Kelu Yao, Xiaogang Xu, Hongchuan Yu, Shuicheng Yan, Xiaobin Hu
Injecting new subjects naturally during streaming video generation requires integrating newly supplied visual references into the existing video while preserving established subjects and the scene. Encoding references independently of the current scene provides little guidance for this integration, while keeping their features in persistent memory can interfere with established context. We propose ReferStream, a framework that requires no additional training and combines reference construction using the current scene with transient cache injection. Joint Latent places reference latents in target regions of the latest scene latent, allowing reference features to be extracted in context. Cache Restoration uses these features to condition the injection chunk, then restores the overwritten global cache entries while retaining the newly generated history. This procedure incorporates new visual conditions without retraining the generator or revising emitted frames. We further introduce ReferStream Bench, a new benchmark with scheduled reference arrivals, evolving instructions, and explicit annotations of subject presence for InShot and MultiShot generation. Evaluation follows the event schedule and measures both the fidelity of new subjects and the preservation of established subjects, alongside video quality, text adherence, and count accuracy. Experiments on ReferStream Bench show higher scores for text adherence, subject similarity, and count accuracy than the compared baselines, including offline methods given all references in advance. Project page: https://xushuolin.github.io/ReferStream/.
Yang Liu, Jinxuan Cai, Yishen Li, Qi Meng Beijing University of Posts and Telecommunications, Zedi Liu, Xin Li Free Org., Chen Qian Shanghai Jiaotong University, Chuan Shi Beijing University of Post and Telecommunication 等 9 位作者
Large language model-based (LLM-based) multi-agent systems (MAS) are increasingly used to extend agentic problem solving via role specialization and collaboration. MAS workflows can be naturally modeled as directed computation graphs, where nodes execute agents or sub-workflows and edges encode dependencies and message passing. However, implementing complex graph workflows in current frameworks still requires substantial manual effort, offers limited reuse, and makes it difficult to integrate heterogeneous external context sources. To overcome these limitations, we present MASFactory, a graph-centric framework for orchestrating LLM-based MAS. It introduces Vibe Graphing, a human-in-the-loop approach that compiles natural-language intent into an editable workflow specification and then into an executable graph. In addition, the framework provides reusable components, skill support, multimodal message handling, and pluggable context integration, as well as a visualizer for topology preview, runtime tracing, and human-in-the-loop interaction. We evaluate MASFactory on seven public benchmarks, validating both reproduction consistency for representative MAS methods and the effectiveness of Vibe Graphing. Our code (https://github.com/BUPT-GAMMA/MASFactory, licensed under Apache-2.0) and video demonstration (https://youtu.be/ANynzVfY32k) are publicly available.
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cs.CL · cs.AI · cs.MA · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 3: System Demonstrations) · 2026 · 正式发表
Fangda Ye National University of Singapore, Kuicai Dong Huawei Technologies Ltd., Xie Zhifei, Yuxin Hu, Yihang Yin University of Edinburgh, Shurui Huang, Shikai Dong, Chen Zhang Huawei International Pte Ltd 等 10 位作者
Recent agentic search frameworks enable deep research via iterative planning and retrieval, reducing hallucinations and enhancing factual grounding. However, they remain text-centric, overlooking the multimodal evidence that characterizes real-world expert reports. We introduce a pressing task: multimodal long-form generation. Accordingly, we propose Deep-Reporter, a unified agentic framework for grounded multimodal long-form generation. It orchestrates: (i) Agentic Multimodal Search and Filtering to retrieve and filter textual passages and information-dense visuals; (ii) Checklist-Guided Incremental Synthesis to ensure coherent image-text integration and optimal citation placement; and (iii) Recurrent Context Management to balance long-range coherence with local fluency. We develop a rigorous curation pipeline producing 8K high-quality agentic traces for model optimization. We further introduce M^2LongBench, a comprehensive testbed comprising 247 research tasks across 9 domains and a stable multimodal sandbox. It enables unified multimodal assessment, fair comparison, and accessible evaluation without commercial APIs. Extensive experiments demonstrate that long-form multimodal generation is a challenging task, especially in multimodal selection and integration, and effective post-training can bridge the gap. Our code is available at https://github.com/fangda-ye/Deep-Report.
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cs.CL · cs.AI · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表