Xiangyu Li, Jincheng Li, Xing Xie, Bin Guan, Shaohua Kevin Zhou, Rui Yan, Ran Su
Whole-slide multiple instance learning can predict diagnostic and prognostic labels from tissue composition while making limited use of spatial organization. Providing coordinates or a graph does not establish that a trained predictor uses tissue neighborhoods. We examine this gap as spatial blindness and hypothesize that early composition learning can weaken supervision of a spatial pathway. We introduce ResTopoMIL, which freezes a learned composition predictor before training a graph residual with a coordinate-reassignment separation loss. Permutation and information analyses distinguish architectural symmetry, available spatial information and the proposed optimization mechanism. On a controlled spatial task, staged training achieved an AUC of 0.987, compared with 0.684 for the same jointly trained architecture. Performance remained high on a composition-only task. Across four WSI classification and five survival benchmarks, ResTopoMIL improved mean primary performance on eight tasks; four improvements remained significant after Holm-adjusted patient-cluster tests. Coordinate-free residual controls recovered some of the gains, while neighborhood destruction reduced performance close to the composition anchor. Neighborhood-preserving transformations and anatomy-stratified perturbations further characterized this dependence. These results support fixing a composition reference as a practical intervention for learning spatial corrections, while retaining additional appearance capacity as a contributing explanation.
Adaptive robot perception systems must balance detector accuracy, inference latency, and energy consumption, particularly when high ambient temperatures cause processors to thermally throttle. We propose Thermal-Headroom Routing (THR), a lightweight model-selection policy that forecasts processor temperature using a closed-form RC thermal model and excludes detector configurations predicted to cross a throttling threshold. We evaluate THR with four YOLO11 configurations across seven real-world perception traces, eight ambient temperatures, and 20 randomized seeds, comparing it with latency-aware routing, fixed-threshold thermostats, duty caps, and a matched-compute-budget control. At ambient temperatures of 45-55 degrees C and a tight inference deadline, THR eliminates throttling in simulation, reduces deadline misses by 3.9-7.5 percentage points, and reduces energy per on-time frame by approximately 12-13% relative to a latency-belief router. A separate experiment using deadline-paced, nonoverlapping frame execution yields miss-rate reductions of 6.2-9.5 percentage points. A tuned thermostat or duty cap can match THR at a fixed operating point; predictive routing is most useful when ambient conditions or calibrated thermal parameters differ from those used to tune static policies. Measurements on an Apple M5 support the single-node heating approximation but do not validate hardware throttling. The results characterize the conditions under which thermal forecasting improves the efficiency and timeliness of resource-constrained robot perception.