Spatial transcriptomics (ST) enables joint characterization of tissue morphology and gene expression. However, 3D volumetric ST acquisition remains expensive. AI-driven methods offer a low-cost alternative but remain limited in accuracy, while recent 2D section-wise ST acquisition still rely on dense grid sampling, resulting in redundant measurements and undersampling of biologically informative regions. To bridge the gap, we propose STRATA, a reinforcement-driven active sampling framework with tri-paradigm adaptation for reconstructing dense 3D transcriptomic maps from sparse voxel-wise ST acquisition. STRATA constructs a 3D graph integrating H&E morphology with single-cell priors and employs a reinforcement learning agent to estimate morphological sparsity and transcriptomic informativeness, enabling budget-aware selection of informative spots. Given these sparse measurements, an adaptive tri-paradigm predictor combines retrieval, regression, and cross-layer imputation through lightweight fusion, dynamically weighting their contributions. Experiments across datasets demonstrate improved sampling efficiency and accuracy, particularly under low-budget settings. Code is available at https://github.com/Junchao-Zhu/STRATA.
Pengna Li, Kangyi Wu, Shaoqing Xu, Fang Li, Lin Zhao, Long Chen Xiaomi, Zhi-Xin Yang University of Macau, Nanning Zheng Xi'an Jiaotong University
Image-goal navigation steers an agent to a target location specified by an image in unseen environments. Existing methods primarily handle this task by learning an end-to-end navigation policy, which compares the similarities of target and observation images and directly predicts the actions. However, when the target is distant or lies in another room, such methods fail to extract informative visual cues, leading the agent to wander around. Motivated by the human cognitive principle that deliberate, high-level reasoning guides fast, reactive execution in complex tasks, we propose Hierarchical Reasoning Navigation (HRNav), a framework that decomposes image-goal navigation into high-level planning and low-level execution. In high-level planning, a vision-language model is trained on a self-collected dataset to generate a short-horizon plan, such as whether the agent should walk through the door or down the hallway. This downgrades the difficulty of the long-horizon task, making it more amenable to the execution part. In low-level execution, an online reinforcement learning policy is utilized to decide actions conditioned on the short-horizon plan. We also devise a novel Wandering Suppression Penalty (WSP) to further reduce the wandering problem. Together, these components form a hierarchical framew ork for Image-Goal Navigation. Extensive experiments in both simulation and real-world environments demonstrate the superiority of our method.
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
The efficiency of long-video inference remains a critical bottleneck, mainly due to the dense computation in the prefill stage of Large Multimodal Models (LMMs). Existing methods either compress visual embeddings or apply sparse attention on a single GPU, yielding limited acceleration or degraded performance and restricting LMMs from handling longer, more complex videos. To overcome these issues, we propose APB-V, a sequence-parallel framework with optimized attention that accelerates long-video inference across multiple GPUs. By distributing approximate attention, APB-V reduces computation and increases parallelism, enabling efficient processing of more visual embeddings without compression and thereby improving task performance. System-level optimizations, such as load balancing and fused forward passes, further unleash the potential of APB-V, delivering speedups of 12.72x, 1.70x, and 1.18x over FlashAttn, ZigZagRing, and APB, without notable performance loss.
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Xi Xiao University of Alabama at Birmingham, Chenrui Ma, Yunbei Zhang Tulane University, Chen Liu Yale University, Zhuxuanzi Wang Cornell University, Yanshu Li, Lin Zhao Northeastern University, Guosheng Hu University of Bristol 等 10 位作者
Low-Rank Adaptation (LoRA) has become a cornerstone of parameter-efficient fine-tuning (PEFT). Yet, its efficacy is hampered by two fundamental limitations: \textit{semantic drift}, arising from treating all update directions with equal importance, and \textit{structural incoherence}, due to adapting layers independently, resulting in uncoordinated and suboptimal updates. To address these issues, we propose \textbf{StructLoRA}, a framework that tackles both limitations through a principled dual-component design: (1) an Information Bottleneck-guided filter that prunes task-irrelevant directions to mitigate semantic drift, and (2) a lightweight, training-only graph-based coordinator that enforces inter-layer consistency to resolve structural incoherence. Extensive experiments across large language models, vision language models, and vision models (including LLaMA, LLaVA, and ViT) demonstrate that \textbf{StructLoRA} consistently establishes a new state of the art, outperforming not only vanilla LoRA but also advanced dynamic rank allocation and sparsity-based methods. Notably, the gains are particularly pronounced in challenging low-rank and low-data regimes. Crucially, since the proposed modules operate only during training, \textbf{StructLoRA} improves performance with \textbf{zero additional inference cost}, shifting the focus of PEFT from mere parameter compression to a more holistic optimization of information quality and structural integrity.
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表