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版本更新 · v2arXiv:2606.26718

基于潜在ODE的心室全心动周期运动建模:从电影MRI到心衰风险预测

A latent ODE approach to full-cycle biventricular cardiac motion modeling from cine MRI

David Brüggemann, Ekaterina Krymova, Firat Özdemir, Jochen von Spiczak, Sebastian Kozerke, Samia Mora, Robert Manka, Mathieu Salzmann 等 9 位作者

AI 速读 基于摘要

作者提出一种结合心率感知神经常微分方程与图网格自编码器的潜在动力学模型,将双心室全心动周期电影MRI运动编码为连续潜在轨迹,并检验其偏离协变量条件先验能否预测新发心力衰竭。

cs.AI · cs.CV

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Cardiac magnetic resonance imaging (CMR) captures rich spatiotemporal information about ventricular structure and motion, but conventional risk models use only a few image-derived indices from selected cardiac phases. We present a latent dynamical model that encodes bi-ventricular anatomy and full-cycle cine motion as a continuous latent trajectory, using heart-rate-aware neural ordinary differential equation (ODE) dynamics and a graph-based mesh autoencoder to reconstruct anatomically consistent 3D+t ventricular motion. A covariate-conditioned prior defines the expected end-diastolic latent state, and a Cox proportional hazards model tests whether deviations from this prior predict incident heart failure. We studied 72,386 UK Biobank participants without baseline cardiovascular disease, including 367 incident heart failure events. In a held-out evaluation subset, adding the latent score to refitted pooled cohort equations improved the stratified C-index from 0.704 to 0.785, compared with 0.764 for seven established cardiac markers. Compared with non-graph and non-ODE approaches, the proposed model gave the best trade-off between reconstruction fidelity, generative realism, and downstream prognostic performance. These results suggest that continuous full-cycle modeling of ventricular motion provides informative cardiac phenotypes beyond conventional CMR summaries, while external validation in more representative patient cohorts is required before clinical risk-prediction use.

新论文 · v1arXiv:2610.38109

Who Called? V33DA: A Physically Verified Multimodal Benchmark for Vocal Attribution in Zebra Finch Groups

Maris Basha, Yuhang Wang, Xiaoran Chen, Longbiao Cheng, Luca Yapura, Anja T. Zai, Mathieu Salzmann, Richard Hahnloser

原文摘要

Deciding which member of an animal group produced a vocalization and where that vocalization was produced are central to studying social communication but are rarely evaluated with physically verified ground truth. Existing resources either localize sounds without identifying the caller, or recognize individuals from isolated vocalizations without reliance on the 3D candidate geometry. We close this gap with V33DA, a dataset-centered multimodal benchmark for spatial vocal attribution in social zebra finches: it comprises 33,625 verified events coupling 5-channel audio with three camera views, calibrated 3D pose for every visible candidate, and per-bird radio telemetry across 10 individuals and three experiments. Caller identity is verified from an on-body accelerometer-derived vibration signal; this channel is withheld from benchmark models and used only by an on-body reference ceiling. Given a detected vocalization and the visible candidate birds, the task is to select the caller. We evaluate it under three regimes: session-disjoint testing on familiar birds from held-out recording dates, held-out-experiment transfer to a new cohort, and leave-one-individual-out evaluation on a bird whose vocalizations are held out from training. Reference methods expose a consistent gap between in-domain accuracy and transfer to unseen individuals: methods that can exploit familiar vocal identity perform well on known callers but degrade sharply on unseen ones, whereas candidate-aware methods preserving explicit spatial reasoning transfer substantially better. The on-body reference stays near-perfect across regimes, confirming the internal consistency of the accelerometer-verified labels. We release V33DA with fixed protocols and code for the evaluated methods, and V33DA++, an unevaluated companion set of verified overlapping-call events and +/-2 s context windows.

cs.SD · cs.CV · cs.LG · q-bio.QM