Natural human-robot interaction requires robots to interpret language and gestures within a 3D environment to support tasks such as pick-and-place and object retrieval. 3D Embodied Reference Understanding (3D-ERU) supports this by identifying the 3D location of a target object from a scene (point-cloud) containing a human pointing gesture and an accompanying language description. However, current 3D-ERU models lack alignment of cross-modal representations and incur high processing costs that increase with the point-cloud's size. To address this, we propose GVT3D, which employs an Embodied Fusion module that jointly models language, gesture, and vision inputs within a shared embedding space, promoting cross-modal alignment. We additionally introduce a foveation approach that selectively processes the point cloud within a coarse region around the estimated pointing direction to reduce computations. GVT3D achieves ~8% higher accuracy and foveation enables 2.95x faster execution while maintaining comparable accuracy, relative to prior 3D-ERU models.
Xiangyu Li, Jincheng Li, Xing Xie, Bin Guan, Shaohua Kevin Zhou, Rui Yan, Ran Su
Whole-slide multiple instance learning can predict diagnostic and prognostic labels from tissue composition while making limited use of spatial organization. Providing coordinates or a graph does not establish that a trained predictor uses tissue neighborhoods. We examine this gap as spatial blindness and hypothesize that early composition learning can weaken supervision of a spatial pathway. We introduce ResTopoMIL, which freezes a learned composition predictor before training a graph residual with a coordinate-reassignment separation loss. Permutation and information analyses distinguish architectural symmetry, available spatial information and the proposed optimization mechanism. On a controlled spatial task, staged training achieved an AUC of 0.987, compared with 0.684 for the same jointly trained architecture. Performance remained high on a composition-only task. Across four WSI classification and five survival benchmarks, ResTopoMIL improved mean primary performance on eight tasks; four improvements remained significant after Holm-adjusted patient-cluster tests. Coordinate-free residual controls recovered some of the gains, while neighborhood destruction reduced performance close to the composition anchor. Neighborhood-preserving transformations and anatomy-stratified perturbations further characterized this dependence. These results support fixing a composition reference as a practical intervention for learning spatial corrections, while retaining additional appearance capacity as a contributing explanation.
Xiangyu Li, Jincheng Li, Tianle Du, Yanheng Li, Haoxuan Che, Yuxin Sun, Long Bai, Liangliang Liu 等 9 位作者
A question about a whole-slide image rarely names every morphological finding needed to answer it. Question-guided patch selection can therefore overlook supporting morphology, while slide-level compression can dilute focal evidence. Inspired by how pathologists combine broad slide review, question-directed examination, and integration of their findings, we introduce BEYONDPATH, a Preserve-Focus-Fuse framework for whole-slide image question answering. Preserve learns a question-agnostic Morphology Bank through answer supervision across multiple questions about each training slide. Focus retrieves questionspecific evidence from all foreground patches, including regions outside the Bank. Fuse integrates the preserved morphology at the retrieved evidence positions through Morphology-on-Visual-Evidence Fusion, producing a fixed 96-token visual prefix. On WSI-Bench, BEYONDPATH achieves an Avg-9 of 0.769 and leads all eight reported report-generation metrics using the same checkpoint. It also achieves 0.639 zero-shot overall accuracy on SlideBench-BCNB. Controlled ablations show complementary benefits from morphology preservation and question-directed retrieval, and support cross-question supervision and fusion at the evidence positions. These results support looking beyond the question's explicit cues: preserving broader slide morphology while retaining the ability to seek evidence for each question.