Spatial transcriptomics (ST) has emerged as a revolutionary approach in the field of tissue analysis that can offer spatial resolved molecular insights for the identification of anomalous regions (AR) on human cancers. Current ST-based methods for detecting AR focus narrowly on the molecular features of local tissue spots, overlooking the matched bulk RNA-seq data that contains crucial diagnostic information. This oversight limits their effectiveness in identifying subtle or heterogeneous tumors, where accurate detection depends on broader genetic context. Besides the genomic signatures, the pathological images can also provide rich visual information to reflect the morphology of AR. To utilize the patient-level diagnostic knowledge and harness complementary information from both histology images and ST, we develop a Bulk RNA-seq Guided Multi-modal Anomalous Regions Detection method (BRGMAR) for the identification of AR from human tissues. Specifically, to effectively model the dependencies in ST, we introduce a Dynamic Multi-Relational Graph Learning (DMRGL) module to adaptively capture complex relationships in ST, including both spatial proximity and gene expression similarity. Then, we design an Optimal Transportation-based Gene Module Alignment (OTGMA) approach to align ST data with patient-level bulk RNA-seq data by matching the compositional and functional similarities of their corresponding gene modules. Finally, we combine the learned genomic features with pathological image representations for accurate AR detection. We evaluate our method on three public available ST datasets for the purpose of identifying cancerous regions from normal tissues, and the experimental results demonstrate the advantage of our method in comparison with the existing studies.
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cs.CV
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表
Zhang, Da, Li, Bingyu, Wang, Feiyu, Zhao, Zhiyuan, Gao, Junyu
Zero-shot object counting (ZSOC) aims to enumerate objects of arbitrary categories specified by text descriptions without requiring visual exemplars. However, existing methods often treat counting as a coarse retrieval task, suffering from a lack of fine-grained quantity awareness. Furthermore, they frequently exhibit spatial insensitivity and degraded generalization due to feature space distortion during model adaptation. To address these challenges, we present QICA, a novel framework that synergizes quantity perception with robust spatial cast aggregation. Specifically, we introduce a Synergistic Prompting Strategy (SPS) that adapts vision and language encoders through numerically conditioned prompts, bridging the gap between semantic recognition and quantitative reasoning. To mitigate feature distortion, we propose a Cost Aggregation Decoder (CAD) that operates directly on vision-text similarity maps. By refining these maps through spatial aggregation, CAD prevents overfitting while preserving zero-shot transferability. Additionally, a multi-level quantity alignment loss (\mathcal L _ MQA ) is employed to enforce numerical consistency across the entire pipeline. Extensive experiments on FSC-147 demonstrate competitive performance, while zero-shot evaluation on CARPK and ShanghaiTech-A validates superior generalization to unseen domains.
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cs.CV
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表
The Aerial Object Goal Navigation, a challenging frontier in Embodied AI, requires an Unmanned Aerial Vehicle (UAV) agent to autonomously explore, reason, and identify a specific target using only visual perception and language description. However, existing methods struggle with the memorization of complex spatial representations in aerial environments, reliable and interpretable action decision-making, and inefficient exploration and information gathering. To address these challenges, we introduce **APEX** (Aerial Parallel Explorer), a novel hierarchical agent designed for efficient exploration and target acquisition in complex aerial settings. APEX is built upon a modular, three-part architecture: 1) Dynamic Spatio-Semantic Mapping Memory, which leverages the zero-shot capability of a Vision-Language Model (VLM) to dynamically construct high-resolution 3D Attraction, Exploration, and Obstacle maps, serving as an interpretable memory mechanism. 2) Action Decision Module, trained with reinforcement learning, which translates this rich spatial understanding into a fine-grained and robust control policy. 3) Target Grounding Module, which employs an open-vocabulary detector to achieve definitive and generalizable target identification. All these components are integrated into a hierarchical, asynchronous, and parallel framework, effectively bypassing the VLM's inference latency and boosting the agent's proactivity in exploration. Extensive experiments show that APEX outperforms the previous state of the art by +4.2% SR and +2.8% SPL on challenging UAV-ON benchmarks, demonstrating its superior efficiency and the effectiveness of its hierarchical asynchronous design.
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cs.CV · cs.CL
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表
Scalable Vector Graphics (SVG) are central to digital design due to their inherent scalability and editability. Despite significant advancements in content generation enabled by Visual Language Models (VLMs), existing text-to-SVG generation methods are limited by a core challenge: the autoregressive training process does not incorporate visual perception of the final rendered image, which fundamentally constrains generation quality. To address this limitation, we propose an Introspective SVG Generation Framework (IntroSVG). At its core, the framework instantiates a unified VLM that operates in a closed loop, assuming dual roles of both generator and critic. Specifically, through Supervised Fine-Tuning (SFT), the model learns to draft SVGs and to provide feedback on their rendered outputs; moreover, we systematically convert early-stage failures into high-quality error-correction training data, thereby enhancing model robustness. Subsequently, we leverage a high-capacity teacher VLM to construct a preference dataset and further align the generator's policy through Direct Preference Optimization (DPO). During inference, the optimized generator and critic operate collaboratively in an iterative "generate-review-refine" cycle, starting from imperfect intermediate drafts to autonomously improve output quality. Experimental results demonstrate that our method achieves state-of-the-art performance across several key evaluation metrics, generating SVGs with more complex structures, stronger semantic alignment, and greater editability. These results corroborate the effectiveness of incorporating explicit visual feedback into the generation loop.
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cs.CV · cs.CL
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表