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The extent to which demographic-associated information is detectable across organs and disease states in routine clinical histopathology remains unclear. Here, we analyzed 1.3 million hematoxylin and eosin whole-slide images from 257,322 patients across 25 organs, using pathology foundation-model representations and multiple-instance learning to systematically map information associated with sex, age group, and self-reported race. Across 69 organ-demographic combinations, demographic attributes were broadly recoverable, with pan-organ mean AUROCs of 0.828 for sex, 0.733 for age group, and 0.662 for self-reported race, and substantial variation across organs. Demographic-class balancing produced relatively small changes in performance, while evaluation within diagnosis-text clusters showed modest attenuation. Under training with diagnosis-based grouping, demographic-associated signals remained detectable across multiple organs, including sex in gastric tissue (AUROC 0.865), age group in breast (0.816), and self-reported race in skin (0.728). Literature-guided analysis of these settings generated candidate histomorphological and contextual explanations for further investigation. Together, these findings provide a systematic map of demographic-associated information in routine histopathology, informing investigations of its sources, assessments of potential shortcut learning, and the development of more interpretable computational pathology models.

ML code should run where researchers choose, not where it was first written. Today, machine learning code mainly lives in two ecosystems, PyTorch on NVIDIA GPUs and JAX on Google TPUs. Migrating repositories between them means building and testing across frameworks and hardware. This migration is (1) a practical need, since it unlocks different hardware for researchers, and (2) a natural benchmark: it involves different frameworks and hardware, covers whole repositories, and is long-horizon and challenging. We introduce XStack, a benchmark that evaluates agents on migrating ML repositories between these two ecosystems. Each agent receives a PyTorch repository and a clean TPU machine and must deliver a JAX repository. Its output passes if it meets our grading criteria, based on the source repository's published result, authenticated and calibrated by us. Migration by agents remains unreliable: Claude Opus 5 passes 75%, GPT-5.6-sol 45%, and every other agent at most 40%. XStack is a step toward freeing ML code from its ecosystem. We release XStack to make progress toward reliable migration across frameworks and hardware measurable.

The growing use of AI in mathematics raises a question: can we detect AI involvement in proofs, separately from AI assistance with writing? Historical arXiv papers, recent papers disclosing substantive AI use, and manuscripts released by OpenAI provide a rich empirical basis for studying this question. However, several challenges remain: lack of matched case-control pairs; potential incompleteness of disclosure; and lack of ready-to-use features designed to capture signals of AI involvement in proofs. To address these challenges, we construct five cohorts comprising 8,281 papers by combining existing manuscripts with those we produced using generative AI. These cohorts span different levels of AI involvement and include matched pairs of papers addressing the same research problems. We then introduce ProofTrace, a framework that represents each paper as a graph of immediate proof support (GIPS) and extracts interpretable features of mathematical organization. Our study yields three discoveries. First, principal-component projections of our features reveal a qualitative gradient of AI involvement, where AI-reworded papers remain close to human papers, the two AI-generated cohorts depart in broadly shared directions, and papers disclosing substantive AI use occupy intermediate positions which shifts toward AI-generated cohorts over time. Second, we identify recurring signatures of AI-generated proofs, such as fewer externally cited results, greater reliance on intermediate conclusions, and altered graph connectivity; many of these signatures persist under controls for research field, manuscript length, or graph size. Finally, in a separate detection experiment, ProofTrace distinguishes human-written papers from those disclosing substantive AI use. Its performance remains stable under AI rewording, whereas the performance of state-of-the-art text-based detectors declines sharply.

While large-scale pretraining has revolutionized language modeling, its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present RAVEN, a novel generative pretraining strategy for sequential EHR data based on Recurrence-Aware next-Visit EveNt prediction. Leveraging a dataset of over one million unique individuals, our model learns to autoregressively generate tokenized clinical events for the next visit conditioned on patient history. We introduce regularization on predicting repeated events and highlight a key pitfall in EHR-based foundation model evaluations: repeated event tokens can inflate performance metrics when new onsets are not distinguished from subsequent occurrences. Furthermore, we empirically investigate the scaling behaviors in a data-constrained, compute-saturated regime, showing that simply increasing model size is suboptimal without commensurate increases in data volume. We evaluate our model via zero-shot prediction for forecasting the incidence of a diverse set of diseases, where it rivals fully fine-tuned representation-based Transformer models and outperforms both standard simulation-based next-token approaches and a prompted medical large language model baseline. Finally, without additional parameter updates, we show that RAVEN can generalize to an external patient cohort under lossy clinical code mappings and feature coverage gaps.

Linear attention compresses context into a fixed-size key-value state for linear-time training and constant-memory inference. Gated delta-rule models decay this state and erase its prediction for an incoming key before writing a new value; Gated DeltaNet-2 (GDN-2) generalizes this with channel-wise decay and decoupled, full-rank erase and write gates. However, we show that state updates are far less sensitive to erasure than to writes: key activation and unit normalization concentrate key energy onto a sparse subset of channels, whereas value writes scale all channels, so the erase gate can be parameterized at lower rank. Furthermore, slow-decaying state rows accumulate much larger norms than fast rows, dominating unweighted readout and forcing stronger write-time erasure to suppress interference. Guided by this analysis, we introduce Muir, which fuses all gates into a sensitivity-allocated low-rank projection, re-weights state rows with a matched-filter readout gate, and reinvests the saved parameters in a wider feed-forward network. Because standard chunkwise algorithms become numerically unstable at the large chunk sizes needed to saturate wide matrix units, we design a parallel update for stable, efficient training. Across 166M-1.34B parameters, Muir lowers perplexity by 1.8-2.0% over GDN-2 and 2.5-3.6% over Transformer, raises commonsense accuracy by up to 1.9 points, and improves extractive recall over GDN-2. At 1.34B, Muir outperforms both baselines on multi-hop and multi-needle recall, extrapolates 2,560x from its 4K training length to 10M-token streams without perplexity drift, and maintains near-100% passkey retrieval to 1M tokens with static readout. Muir achieves these gains while matching GDN-2 throughput, reaching its 100B-token validation loss 1.2x faster, and training 2.7x faster than Transformer at 32K.