Before AI can be trusted to discover new science, it should be able to reproduce what science already knows. Reproduction provides a rigorous checkpoint for an AI scientist: the target claim is known, yet recovering it still requires translating an incomplete scientific description into an executable experiment and producing evidence that can be independently verified. Existing research-reproduction benchmarks largely focus on AI and machine learning, where experiments share relatively homogeneous software stacks. Extending this capability across scientific disciplines introduces a different challenge: agents must operate domain-specific scientific software, make physical and numerical choices, diagnose long-running computations, and distinguish valid evidence from merely plausible outputs. We introduce PAPERBENCHX, a benchmark of 93 expert-constructed paper-reproduction tasks spanning 12 research areas across electromagnetics, photonics, chemistry, materials science, biology, and robotics. Each task provides the source paper, a public task specification, and a domain-native scientific environment involving specialized scientific software. Agents must reconstruct a key experiment, execute and diagnose it, and deliver a runnable workflow that supports the target scientific claim. To evaluate scientific validity rather than surface-level agreement, we replay every submission from scratch and score only regenerated evidence against expert-validated criteria. Across 10 frontier agent configurations, the best configuration fully reproduces only 14% tasks under the 90% threshold. Meanwhile, mean rubric scores range from 27.53% to 59.08%, indicating that substantial partial progress rarely translates into complete scientific reproduction. These results reveal a large gap between paper understanding and reliably producing reproducible scientific evidence.
Chuming Wei, Churui Yang, Zihan Zhang, Ruien Li, Wusheng Zhang, Yan Zhang, Guangwen Yang
Large Language Models (LLMs) can generate fluent responses to diverse user requests, yet streaming may expose users to harmful content before generation is complete. Existing guardrails face two limitations in this setting. First, post-hoc moderation at response or chunk boundaries delays intervention, risking harmful exposure when content is released before verification. Second, even with token-level detection, coarse response-level supervision does not specify when harmful content begins, while fixed-layer readouts may miss relevant safety signals at other depths. To address these limitations, we introduce ADTGuard, which checks each token before release, progressively refines token-level training targets, and adapts layer selection to the current prefix. ADTGuard models risk across depth and time through Depth-Time Safety Dynamics (DTSD), which integrates safety evidence across layers at each token and uses it to guide risk accumulation over successive tokens. To adapt the choice of observation layers to the current prefix, we propose the Causal Depth Router (CDR). With only response-level labels available, we further develop Risk-Onset Target Refinement (RTR) to progressively construct token-level training targets for both components. Through extensive experiments across multiple safety benchmarks, we demonstrate that ADTGuard consistently achieves strong streaming detection performance, matching or surpassing state-of-the-art safeguards while requiring only 16M trainable parameters and maintaining competitive per-token latency.
Tool-using language agents increasingly modify external systems, yet most runtime safeguards allocate scrutiny by generic uncertainty scores or coarse mutation heuristics. We introduce CASEL (Consequence-Aware Selective Execution Layer), a model-agnostic runtime allocation policy that combines calibrated failure probability, state-dependent consequence, reversibility, ambiguity, and evidence freshness to choose, for each proposed tool call, among direct execution, verification, sandboxing, clarification, approval, and abstention by minimizing a per-mode cost. We formalize direct execution as selective prediction and state and test the validity conditions of a finite-sample threshold and a trajectory risk ledger. In a controlled simulation over 20 seeds with 120,000 test actions each, in which every method has the same intervention menu and the same compute cost, CASEL reduces harmful-side-effect trajectories from 14.75 percent for an uncertainty-ranked gate to 7.02 percent and mean normalized harm from 0.184 to 0.123. A gate ranked by the product of failure probability and consequence reaches similar harm (5.82 percent, 0.120) but sends 45 percent more actions to human approval, and removing reversibility-aware routing raises the rate to 15.53 percent. A trajectory-level risk budget, in contrast, increases harm at equal cost (11.82 percent). Intervention effectiveness is assumed, not measured: the results rank allocation rules under the simulator's assumptions and do not establish deployment effectiveness.
Yan Zhang, Jiong Tuo, Meng Ding, Yuheng Ma, Di Wang
Sparse linear regression is a fundamental problem in high-dimensional statistics, and its private counterparts leave a large gap between the central and the local model of differential privacy. Shuffled differential privacy (SDP) sits between the two, offering accuracy closer to the central model without the trust requirement of a central curator. This paper studies sparse linear regression under both non-interactive and interactive SDP protocols. In the non-interactive setting, any non-interactive $(ε,δ)$-SDP protocol is shown to incur an $\ell_2$-norm estimation error of $Ω( \frac{\sqrt{dk}}{nε} )$ with dimension $d$, sparsity $k$, and $n$ users, revealing an inherent dimensionality barrier. In addition, a non-interactive algorithm is proposed that achieves an $\ell_2$-norm upper bound of $\tilde{\mathcal{O}}( \sqrt{\frac{k}{n}} + \frac{d\sqrt{k}}{nε})$. To overcome this barrier, we turn to the interactive user-level setting, where each user holds $m$ samples. A two-round interactive algorithm is developed that first recovers the support through a heavy hitter step and then estimates the parameter, achieving an error of $\tilde{\mathcal{O}}( \sqrt{\frac{k}{nm}} + \frac{k}{n\sqrt{m}ε} )$ with no polynomial dependence on $d$. Furthermore, by extending the score attack framework to user-level data, a new lower bound $Ω( \sqrt{\frac{k\log(d/k)}{nm}} + \frac{k\log(d/k)}{n\sqrt{m}ε} )$ is established for any user-level $(ε,δ)$-DP, showing that the proposed algorithm is near-optimal with only a gap of the factor $\log(d/k)$.
Automated fake news detection is vital on social media, where fake news is easily rewritten to fool detectors. However, existing approaches typically rely on superficial writing cues or single-style text rewrites, resulting in poor robustness under diverse cosmetic modifications. We construct MANTIS-Bench, a multi-axis presentation-attack benchmark that pairs original news with rewritten views across writing style, emotional expression, and dissemination framing. We further propose MANTIS, an instance-adaptive adversarial framework enabling dynamic worst-case training tailored to each news article with zero inference-time overhead. This reframes fake news defense from heuristic format smoothing into targeted, fact-invariant credibility assessment. Experiments on MANTIS-Bench show that MANTIS reduces the Union Attack Success Rate (UASR) by 3.55 percentage points relative to SheepDog on GossipCop and consistently outperforms prior single-axis defenses on Macro-F1 while maintaining competitive clean accuracy, demonstrating the effectiveness of multi-axis and instance-adaptive worst-case training.
Artificial intelligence doctor assistants (AIDAs) help streamline clinical decision-making and reduce physician workload. While existing systems primarily utilize Large Language Models (LLMs) or retrieval-augmented generation (RAG), these methods typically retrieve static facts—whether as text passages or structured graphs—lacking the explicit logical pathways essential for multi-step reasoning. In this paper, we propose the AIDA-SEAT framework to provide reliable clinical decision-making support. First, we design the state-evaluation-action tree (SEAT), which covers diagnosis, treatment, and examination. To develop this tree, we refine and transform SEAT collected from medical documents and doctors. Then, we propose an adaptive method to select optimal trees tailored to the current patients’ state. Finally, we leverage LLMs to perform state assessment, evaluation, and action execution based on the tree, thereby generating reliable responses. To evaluate the effectiveness of our method, we conducted extensive experiments on a self-built dataset. Our method achieves 1.01% higher than current state-of-the-art (SOTA) baselines across five departments, including common RAG-based methods. Furthermore, analysis of 200 consultation records during deployment on an online hospital revealed that system-assisted responses are 24.16 seconds faster on average than manual ones, improving efficiency by 26.85%.
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cs.CL · cs.AI
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 6: Industry Track) · 2026 · 正式发表
Han Zhang, Zihan Gu Institute of Information Engineering, Chinese Academy of Sciences, Zhiyuan Wang, Tianyi Ma, Jiacheng Lu Shanghai Jiao Tong University, Xinyan Zhang independent, Yuhao Wei, Cheng Hua Shanghai Jiaotong University
While Large Language Models (LLMs) achieve high accuracy on established Classical Chinese Poetry benchmarks, it remains challenging to distinguish transferable Linguistic-Aesthetic Reasoning from reliance on familiar pre-training patterns. To address this issue, we introduce Neo-Classic, an evaluation benchmark that combines a constructionist Out-of-Sample (OOS) dataset with a suite of reverse understanding probes. Unlike traditional benchmarks that rely on verification or generation over historical corpora, Neo-Classic comprises strictly metrical poetry authored by contemporary experts, reducing the possibility of direct retrieval. We evaluate state-of-the-art models, including Qwen3-Max, Gemini-3-Pro, and DeepSeek-V3.2, across five behavioral probes designed to test hierarchical constraint satisfaction. Our results reveal two primary limitations. First, a performance gap of 20%–50% emerges when models transition from historical to contemporary texts. Second, models exhibit substantial difficulties in discourse-level ordering tasks, with standard accuracy remaining low (0–13%). Although expert-level guidance improves the performance of reasoning-enhanced models to 36%, a notable gap with human experts persists. These findings suggest that while current LLMs capture local formal patterns, they struggle with global hierarchical planning required for robust Linguistic-Aesthetic Reasoning.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Zihan Gu Institute of Information Engineering, Chinese Academy of Sciences, TianYi Zhang University of the Chinese Academy of Sciences, Xinyan Zhang independent, Zhiyuan Wang, Han Zhang, Yuhao Wei, Jiacheng Lu Shanghai Jiao Tong University, Tianyi Ma 等 11 位作者
Model editing provides a promising mechanism for updating large language models (LLMs) without expensive retraining. Existing approaches, particularly locate-and-edit methods based on least-squares optimization, aim to introduce targeted knowledge changes while preserving pre-trained behavior. In this work, we show that this objective is fundamentally fragile under standard single-edit evaluation protocols. We first develop a unified theoretical framework that characterizes activation-based editing as a constrained intervention on intermediate representations. Within this framework, we demonstrate that least-squares edits cannot, in general, isolate target updates from unrelated activations, giving rise to unavoidable interference that accumulates with successive edits. Crucially, this degradation can remain undetected in single-edit settings when assessed using conventional success and locality metrics. To expose such hidden instabilities, we introduce an uncertainty-based evaluation protocol that combines structured semantic perturbations with uncertainty quantification based on Sampling with Perturbation for UQ. By measuring edit-induced growth in aleatoric and epistemic uncertainty, our method reveals local knowledge conflicts that are invisible to existing benchmarks. Extensive experiments across multiple models, datasets, and editing algorithms show that both least-squares and other parameter-update-based methods consistently increase post-edit uncertainty. Together, our results suggest that current evaluation practices substantially overestimate the reliability of single-edit model editing, and that uncertainty-based diagnostics are necessary for assessing edit stability.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Sihong Wu, Owen Jiang University of Pennsylvania, University of Pennsylvania, Yilun Zhao Yale University, Tiansheng Hu, Yiling Ma King Abdullah University of Science and Technology, Kaiyan Zhang Yale University, Manasi Patwardhan Tata Consultancy Services Limited, India, Arman Cohan Yale University and Allen Institute for Artificial Intelligence
Peer review is a multi-stage process involving reviews, rebuttals, meta-reviews, final decisions, and subsequent manuscript revisions. Recent advances in large language models (LLMs) have motivated methods that assist or automate different stages of this pipeline. In this survey, we synthesize techniques for (i) peer review generation, including fine-tuning strategies, agent-based systems, RL-based methods, and emerging paradigms to enhance generation; (ii) after-review tasks including rebuttals, meta-review and revision aligned to reviews; and (iii) evaluation methods spanning human-centered, reference-based, LLM-based and aspect-oriented. We catalog datasets, compare modeling choices, and discuss limitations, ethical concerns, and future directions. The survey aims to provide practical guidance for building, evaluating, and integrating LLM systems across the full peer review workflow.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Pengfei Li, Shijie Wang, Fangyuan Li, Yikun Fu, Kaifeng Liu, Kaiyan Zhang, Dazhi Zhang Harbin Institute of Technology, Yuqiang Li 等 10 位作者
Reinforcement learning (RL) paradigms have demonstrated strong performance on reasoning-intensive tasks such as code generation. However, limited trajectory diversity often leads to diminishing returns, which constrains the achievable performance ceiling. Search-enhanced RL alleviates this issue by introducing structured exploration, which remains constrained by the single-agent policy priors. Meanwhile, leveraging multiple interacting policies can acquire more diverse exploratory signals, but existing approaches are typically decoupled from structured search. We propose MARS^2 (Multi-Agent Reinforced Tree-Search Scaling), a unified RL framework in which multiple independently-optimized agents collaborate within a shared tree-structured search environment. MARS^2 models the search tree as a learnable multi-agent interaction environment, enabling heterogeneous agents to collaboratively generate and refine candidate solutions within a shared search topology. To support effective learning, we introduce a path-level group advantage formulation based on tree-consistent reward shaping, which facilitates effective credit assignment across complex search trajectories. Experiments on code generation benchmarks show that MARS^2 consistently improves performance across diverse model combinations and training settings, demonstrating the effectiveness of coupling multi-agent collaboration with tree search for enhancing reinforcement learning. Our code is publicly available at https://github.com/TsinghuaC3I/MARTI.
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cs.CL · cs.MA
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Boci Peng, Xiao Liu University of Macau and Guangdong Institute of Intelligence Science and Technology, Zhuhai, China, Boren Hu, Yun Zhu Shanghai Artificial Intelligence Laboratory, Xuanbo Fan Peking University, Yanwei Yue Peking University, Chunyu Yang, Yan Zhang Peking University
Retrieving coherent evidence subgraphs is critical for Knowledge Base Question Answering (KBQA). Existing paradigms often treat facts independently, rely on biased heuristics, or employ myopic search, failing to optimize collective subgraph utility. In this paper, we propose COSMOS (Connectivity-Oriented Submodular Maximization for Optimal Subgraph Retrieval), a unified framework that formalizes evidence retrieval as a constrained submodular maximization problem. This formulation mathematically captures the trade-off between information relevance and structural complexity. To tractably solve this combinatorial challenge, COSMOS employs a decompose-and-conquer strategy, which first performs a seed-guided greedy expansion to maximize local semantic utility, followed by a topology-aware component aggregation to bridge disjoint evidence clusters via Maximum Spanning Tree aggregation. Guided by theoretical bounds, we introduce Structure-Aware Contrastive Tuning to align semantic space with KG topology. Experimental results on WebQSP, CWQ, and \text{M}^3\text{GQA} benchmarks demonstrate that COSMOS achieves state-of-the-art performance.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Ying Zhan, Xiuqi Tang, Yan Zhang, Xiao Tan Southeast University, Dian Shen, Zhou Yu Columbia University, Beilun Wang Southeast University
Lipid nanoparticles (LNPs) can deliver cargos to both tumor and immune cells, playing a crucial role in biomedicine. Traditional approaches rely on experimental screening and expert knowledge, which can be costly and time-consuming. Recent methods based on language models have accelerated this process using deep learning. Although these methods can retrieve molecules for fusion or rank candidates from existing libraries, they are still limited by the scope of known formulations. In this work, we propose a method, LiGen, to generate lipid molecules efficiently and actively, facilitating the discovery of high-performing LNP formulations. We first train a lipid-specific molecular language model, LiCore, to learn hidden representations of lipid molecules. We then explore the learned latent space to generate improved candidate formulations. This process is guided by a trained predictor, which evaluates delivery efficiency and provides directional signals. In reconstruction tasks, LiCore achieves nearly perfect reconstruction output with a low invalid ratio on both the LNP-Virtual900k and LNP-Exp12k datasets. The predictor consistently improves ranking-oriented metrics across multiple cell lines, with our method outperforming the best baselines by an average of 4.1%, 10.8%, and 8.1% in Top-50, Top-10, and Top-5 identification accuracy, respectively. Guided by the predictor, LiGen generates novel lipid candidates that achieve a 30.7% improvement over baseline methods on average, with some samples exceeding 50% improvement.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Luise Ge Washington University, Saint Louis, Yongyan Zhang, Yevgeniy Vorobeychik Washington University, St. Louis
The use of large language models either as decision support systems, or in agentic workflows, is rapidly transforming the digital ecosystem. However, the understanding of LLM decision-making under uncertainty remains limited. We initiate a comparative study of LLM risky choices along two dimensions: (1) prospect representation (explicit vs. experience-based) and (2) decision rationale (explanation). Our study, which involves 20 frontier and open LLMs, is complemented by a matched human subjects experiment, which provides one reference point, while an expected payoff maximizing rational agent model provides another. We find that LLMs cluster into two categories: reasoning models (RMs) and conversational models (CMs). RMs tend towards rational behavior, are insensitive to the order of prospects, gain/loss framing, and explanations, and behave similarly whether prospects are explicit or presented via experience history. CMs are significantly less rational, slightly more human-like, sensitive to prospect ordering, framing, and explanation, and exhibit a large description-history gap. Paired comparisons of open LLMs suggest that a key factor differentiating RMs and CMs is training for mathematical reasoning.
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cs.CL · cs.AI
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Songtao Jiang, Yuan Wang, Ruizhe Chen, Yan Zhang ByteDance Inc., Ruilin Luo, Bohan Lei Zhejiang University, Yeying Jin, Sibo Song Alibaba Group 等 12 位作者
While reinforcement learning from verifiable rewards (RLVR) has been proven highly effective for enhancing reasoning, its application to medical visual question answering (Med-VQA) is hampered by models producing reasoning inconsistent with either the visual evidence or the final answer. Our analysis reveals a critical flaw in RLVR training: it paradoxically encourages models to disregard visual evidence and generate answers that contradict their own reasoning. This degradation is most pronounced in specialized medical modalities (e.g., Fundus, Ultrasound) where base VLMs lack robust understanding, a failure we attribute to a flawed reward mechanism exacerbated by the scarcity of diverse training data. To tackle this, we introduce Med-Zero-17K, a large-scale dataset spanning over 30 modalities and 24 clinically relevant tasks, and the Multi-Consistency Reward (MCR) framework, which explicitly rewards both perceptual grounding and logical coherence. Extensive experiments validate our approach: integrating MCR into the RLVR framework delivers robust performance gains. This success stems from our crucial finding that rewarding internal consistency is significantly more effective than attempting to judge reasoning correctness. Furthermore, MCR proves highly versatile, exhibiting strong generalization across diverse VLM backbones, compatibility with RL algorithms like GRPO and DPO, and extending its effectiveness to 3D VQA tasks and R1-style training paradigms. Code and dataset will be released.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表