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arXiv:2611.09741 · v1

Research Collaborations Within and Across Disciplines in NIH-Funded Atlas Programs

首次提交 2026-11-07 01:12
版本更新 2026-11-07 01:12
雷达观测 2026-11-09 13:22
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摘要

The National Institutes of Health (NIH) fund several programs (aka consortia) that support the construction of organ-specific or whole person atlases. These initiatives are designed to build comprehensive open reference datasets while advancing knowledge graphs, analytics, visualizations, and user interfaces needed to explore multiscale human atlas data. Here, we compare the Human Tumor Atlas Network (HTAN), Human BioMolecular Atlas Program (HuBMAP) and Cellular Senescence Network (SenNet) to examine collaboration by consortium component (CC) and researcher role and its relation to scientific impact. We retrieved 884 NIH award records and identified 1,255 focal publications acknowledging these awards, involving 8,952 researchers; compiled 99,108 citing publications covering 93% of the focal publications; constructed co-authorship networks; and as single-project publications or internal collaborations (IC), including intra-CC and inter-CCs collaborations. within each atlas program. Results show that IC publications are rare but involve many funded projects and principal investigators (PIs). Technology-oriented CCs tend to engage in intra-CC collaboration, whereas experimental-oriented CCs often collaborate across CCs of the same type. Compared with other researchers, PIs exhibited a significantly stronger association with inter-CCs than with single-project publications. IC publications have higher mean Relative Citation Ratios than single-project publications. Inter-CCs publications have significantly higher cumulative and annual citation levels in the first five post-publication years. Study methods and results can be used to inform the funding, management, and impact reporting for future Big Science programs that bring together 300+ experts from different disciplines to address major research challenges.

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该研究比较HTAN、HuBMAP和SenNet三个NIH图谱联盟的内部合作模式及其与科学影响力的关系。

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v1 · 2026-11-07 01:12 · 最新观测版本

Research Collaborations Within and Across Disciplines in NIH-Funded Atlas Programs

The National Institutes of Health (NIH) fund several programs (aka consortia) that support the construction of organ-specific or whole person atlases. These initiatives are designed to build comprehensive open reference datasets while advancing knowledge graphs, analytics, visualizations, and user interfaces needed to explore multiscale human atlas data. Here, we compare the Human Tumor Atlas Network (HTAN), Human BioMolecular Atlas Program (HuBMAP) and Cellular Senescence Network (SenNet) to examine collaboration by consortium component (CC) and researcher role and its relation to scientific impact. We retrieved 884 NIH award records and identified 1,255 focal publications acknowledging these awards, involving 8,952 researchers; compiled 99,108 citing publications covering 93% of the focal publications; constructed co-authorship networks; and as single-project publications or internal collaborations (IC), including intra-CC and inter-CCs collaborations. within each atlas program. Results show that IC publications are rare but involve many funded projects and principal investigators (PIs). Technology-oriented CCs tend to engage in intra-CC collaboration, whereas experimental-oriented CCs often collaborate across CCs of the same type. Compared with other researchers, PIs exhibited a significantly stronger association with inter-CCs than with single-project publications. IC publications have higher mean Relative Citation Ratios than single-project publications. Inter-CCs publications have significantly higher cumulative and annual citation levels in the first five post-publication years. Study methods and results can be used to inform the funding, management, and impact reporting for future Big Science programs that bring together 300+ experts from different disciplines to address major research challenges.

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