← 研踪 PaperTrailCVF · CVPR 2026:cvf:ca79a6dc18f3b5115e9418df9767bf24 · 记录 #1
Factorized Context Aggregation for Robust Cancer Risk Estimation via Soft Re-Ranked Retrieval and Hierarchical Anchors
来源日期（仅到年份） 2026
来源记录日期 2026
雷达观测 2026-11-05 02:15
摘要
Accurate cancer risk assessment is critical for personalized treatment planning. While multimodal models that integrate histopathology with complementary data modalities (e.g., genomics, or clinical reports) exhibit superior prognostic capability, they typically assume full data availability, an unrealistic expectation in real-world clinical settings. In contrast, histopathology slides are routinely collected, universally accessible, and information-rich, making them a practical anchor for robust survival prediction. In this study, we propose a novel framework that leverages histopathology as a basis for outcome prediction, while using other data modalities when training the models. Extensive experiments across eight cancer types and scenarios, including various data modalities, demonstrate that our model outperforms all baselines, with up to 8% gains over methods that solely use histopathology at training time, and a 1.4% gap compared to models that utilize all data modalities. Our model also stratifies patients into meaningful risk groups in 67% of risk stratification scenarios (vs. 50% for best SOTA), generalizes well under varying modality missingness, and matches the best SOTA even with 40% higher rate of missing data during training. It also preserves semantic alignment in zero-shot settings. These results highlight the practical utility and robustness of our approach for real-world cancer risk prediction in resource-limited or modality-incomplete settings. Code is available at: https://github.com/pazadimo/fca-robust-risk-estimation
论文发现出处
这些页面提供论文线索，不代表同行评审或质量认证。
观测到的版本
平台记录号代表本站观测到的元数据变化，不是作者修订号。来源日期仅到月份或年份时，按该月或该年首日存档。
记录 #1 · 2026 · 最新观测版本
Factorized Context Aggregation for Robust Cancer Risk Estimation via Soft Re-Ranked Retrieval and Hierarchical Anchors
Accurate cancer risk assessment is critical for personalized treatment planning. While multimodal models that integrate histopathology with complementary data modalities (e.g., genomics, or clinical reports) exhibit superior prognostic capability, they typically assume full data availability, an unrealistic expectation in real-world clinical settings. In contrast, histopathology slides are routinely collected, universally accessible, and information-rich, making them a practical anchor for robust survival prediction. In this study, we propose a novel framework that leverages histopathology as a basis for outcome prediction, while using other data modalities when training the models. Extensive experiments across eight cancer types and scenarios, including various data modalities, demonstrate that our model outperforms all baselines, with up to 8% gains over methods that solely use histopathology at training time, and a 1.4% gap compared to models that utilize all data modalities. Our model also stratifies patients into meaningful risk groups in 67% of risk stratification scenarios (vs. 50% for best SOTA), generalizes well under varying modality missingness, and matches the best SOTA even with 40% higher rate of missing data during training. It also preserves semantic alignment in zero-shot settings. These results highlight the practical utility and robustness of our approach for real-world cancer risk prediction in resource-limited or modality-incomplete settings. Code is available at: https://github.com/pazadimo/fca-robust-risk-estimation
查看此版本解读 →查看此版本原文 ↗