AI 速览：提出自主AI系统PPE，从自然语言查询出发自动完成多模态地理空间数据检索、融合与模型搜索，并在多个健康、风险与流行病预测任务上报告优于专家基线。
Addressing critical global challenges, from food security and disaster risk to disease outbreaks and socio-economic vulnerability, demands high-fidelity geospatial modeling. However, building predictive planetary models remains bottlenecked by a fragmented data ecosystem, requiring manual data retrieval, multimodal data curation and fusion along with iterative model selection. We present the Planetary Prediction Engine (PPE), an autonomous AI system that executes this end-to-end workflow directly from natural-language queries. PPE synthesizes multimodal datasets on the fly, retrieving spatiotemporally relevant covariates across open-web and Earth observation platforms (Data Commons, Google Earth Engine) and fusing them with geospatial foundation model embeddings (PDFM, AlphaEarth). Simultaneously, it searches over task-tailored model architecture families with automated overfitting guards. Across diverse tasks, geographies, and scientific domains, PPE consistently outperforms state-of-the-art or manually tuned expert baselines. For US spatial regression, PPE improves mean $R^2$ across 21 CDC health indicators (76.8% vs. 60.0%), FEMA national risk indices (64.9% vs. 60.0%), and the Social Vulnerability Index (66.2% vs. 58.6%). For spatial downscaling in data-scarce settings, PPE integrates localized proxies to double baseline accuracy in Nigerian food security indicators ($R^2$ of 66.1% vs. 31.5%). For epidemiological nowcasting of the 2026 DRC Bundibugyo Ebola outbreak, PPE achieves a Recall@10 of 83.3% (identifying 15 of 18 newly invaded health zones across five weekly forecasts), a +10.3 percentage-point improvement over the public state-of-the-art modeling (~73%). By combining autonomous multimodal planetary data discovery with targeted model optimization, PPE lowers the technical barrier to planetary-scale analytics, enabling rapid, customized, expert-level deployment.
Accelerating scientific discovery with Co-Scientist
Juraj Gottweis, Wei-Hung Weng, Alexander Daryin, Tao Tu, Petar Sirkovic, Artiom Myaskovsky, Grzegorz Glowaty, Felix Weissenberger 等 51 位作者
AI 速览：基于Gemini的多智能体系统Co-Scientist通过生成、批判和进化假设，在生物医学领域辅助科学家发现新知识。
Scientific discovery is driven by scientists generating novel hypotheses for complex problems that undergo rigorous experimental validation. To augment this process, we introduce Co-Scientist, a multi-agent AI system built on Gemini for structured scientific thinking and hypothesis generation. Co-Scientist aims to help scientists discover new original knowledge. Conditioned on their research objectives and prior scientific evidence, it formulates demonstrably novel research hypotheses for experimental verification. The system's design involves agents continuously generating, critiquing and refining hypotheses accelerated by scaling test-time compute. Key contributions include: (1) a multi-agent architecture with an asynchronous task execution framework for flexible compute scaling; (2) a tournament evolution process for self-improving hypotheses generation. Automated evaluations show continued benefits of test-time compute scaling, improving hypothesis quality over time. While general purpose, we focus the validation in three biomedical applications: drug repurposing, novel target discovery, and explaining mechanisms of anti-microbial resistance. Specifically, Co-Scientist helped identify new drug repurposing candidates and synergistic combination therapies for acute myeloid leukemia, which were validated through in vitro experiments. These real-world validations demonstrate the potential of Co-Scientist to accelerate scientific discovery and usher in an era of AI empowered scientists.
AI 速览：作者报告，经过恰当提示并配备合适工具后，现代LLM能为几乎任意提示稳健生成高质量定制界面，人类偏好显著超过标准markdown输出。
AI models excel at creating content, but typically render it with static, predefined interfaces. Specifically, the output of LLMs is often a markdown "wall of text". Generative UI is a long standing promise, where the model generates not just the content, but the interface itself. Until now, Generative UI was not possible in a robust fashion. We demonstrate that when properly prompted and equipped with the right set of tools, a modern LLM can robustly produce high quality custom UIs for virtually any prompt. When ignoring generation speed, results generated by our implementation are overwhelmingly preferred by humans over the standard LLM markdown output. In fact, while the results generated by our implementation are worse than those crafted by human experts, they are at least comparable in 50% of cases. We show that this ability for robust Generative UI is emergent, with substantial improvements from previous models. We also create and release PAGEN, a novel dataset of expert-crafted results to aid in evaluating Generative UI implementations, as well as the results of our system for future comparisons. Interactive examples can be seen at https://generativeui.github.io