让下一篇重要论文，不再错过。

BRIDGE: Learning Brain-Gut Metabolic Evidence for Alzheimer's Disease Diagnosis

Pengli Zhu, Ruxi Chang, Tianliang Yao, Yu Jiang, Shengyuan Liu, Yiyang Lin, Xiaoyi Duan, Shuang Wu 等 10 位作者

Alzheimer's disease (AD) diagnosis may benefit from gut metabolic information associated with brain-gut interactions, yet existing models largely analyze cerebral glucose metabolism alone. Although whole-body fluorodeoxyglucose positron emission tomography (FDG-PET) can provide paired brain-gut observations, routine brain examinations rarely include gut imaging, limiting direct use of this information for diagnosis. In this paper, we present BRIDGE (Brain and Gut Representation Integration via Distribution-Guided Enhancement), a two-stage framework for transferring brain-gut metabolic knowledge to brain-only diagnosis. Specifically, BRIDGE integrates a conditional brain-to-gut latent transport module and a disease-evidence-guided cerebral pathway to capture subject-specific cross-organ correspondence and disease-relevant cerebral representations. For the cerebral pathway, a large language model (LLM) helps organize literature-derived descriptors into human-approved semantic anchors that guide feature learning. Additionally, we introduce a counterfactual-guided residual fusion mechanism, which uses matched and non-matched virtual-gut evidence to supervise a confidence gate and dynamically regulate the contribution of transported cross-organ information. At inference, BRIDGE exploits complementary gut-related context using brain PET alone, without measured gut PET. Extensive experiments across public and private cohorts demonstrate that BRIDGE outperforms brain-only and cross-organ baselines, achieving AUC gains of 6.0% and 5.2% over its brain-only counterpart for CN/MCI and CN/AD diagnosis, respectively. Notably, its ability to transfer complementary brain-gut metabolic context while preserving brain PET as the sole inference input highlights its potential for clinically practical diagnosis. Our code is available at https://github.com/CUHK-AIM-Group/BRIDGE.

尚无 AI 解读，展示原文摘要

G-Cap: A Game Character Caption Generator

Yang Yang SUN YAT-SEN UNIVERSITY, Feng Hu IEG, Tencent, Haiming Zhang Tencent AI Research, XU Cheng , Tsinghua University, Gui Zheng, Liang Yao SUN YAT-SEN UNIVERSITY, Wenqi Ren SUN YAT-SEN UNIVERSITY

While Large Vision-Language Models (LVLMs) have demonstrated remarkable proficiency in image captioning, existing research primarily focuses on real-world scenarios, leaving surreal, highly stylized, and semantically hybrid virtual-world scenarios significantly underexplored. In this work, we introduce Game Character Captioning, a novel task designed to evaluate LVLMs’ capability to perceive and describe game character from the virtual-world. To facilitate evaluation, we establish GC-Bench, a manually annotated benchmark, and propose Graph-F1 to effectively assess performance on this task. Our evaluation reveals that: (1) current state-of-the-art LVLMs, including closed-source giants such as Gemini 3 Pro and GPT-5.1, struggle to maintain the high performance seen in real-world scenarios; and (2) a notable gap exists between open-source and closed-source models. To bridge this gap, we construct GC-148K, a large-scale dataset generated via a specialized data pipeline, and develop the G-Cap series. Experiments demonstrate that G-Cap series rivals the performance of advanced closed-source models at a lower cost, offering an efficient solution for industrial-grade production environment.

尚无 AI 解读，展示原文摘要

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表