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版本更新 · v2arXiv:2610.28631

AEON: Unifying Video and 3D World Models

Weiqi Zhang, Wenyuan Zhang, Yu-Shen Liu, Junsheng Zhou

原文摘要

Current world models for explicit world simulation typically follow two distinct pathways: (1) video generative models (e.g., Sora), which simulate realistic appearances but fail to preserve 3D consistency; and (2) 3D generative models (e.g., Marble), which generate geometrically consistent scenes but often yield static, less realistic observations. We present AEON, a unified framework that bridges video-based and 3D-based world models and combines the benefits of both. The key insight of AEON lies in a generative model that operates within the text- or image-conditioned video latent space while producing renderable 4D graphics primitives---specifically, 4D Gaussian Splatting (4DGS)---as the explicit world representation. We train a 4D reconstruction model to predict both 4DGS and camera poses from monocular videos, serving as our initialized 4D decoder. Furthermore, we design a domain adapter that translates generative video latents into reconstructive 4D latents through a distillation process on the video VAE. AEON naturally supports video-based world modeling by rendering 4DGS at predicted camera trajectories, and constructs a persistent 4D environment with scene dynamics for realistic world simulation. Consequently, AEON empowers a diverse range of world modeling applications and achieves state-of-the-art performance on standard benchmarks. Project Page: https://weiqi-zhang.github.io/AEON

cs.CV

版本更新 · v3arXiv:2607.25242

Medical world models in healthcare: capabilities, evidence, and trustworthy clinical translation

Wanshu Fan, Zhongxiu Cong, Zhaoyan Chen, Zhuanfeng Jin, Qi Ai, Haifan Gong, Congyu Liao, Xiaofeng Liu 等 10 位作者

原文摘要

Medical world models offer a framework for extending medical artificial intelligence beyond static prediction by representing evolving patient states and modelling how they change over time and in response to clinical interventions. This Review uses structured narrative synthesis and reproducible evidence mapping to define conceptual boundaries, technical foundations, application domains, and clinical evidence requirements. We screened 1,455 unique records and assembled a corpus of 300 sources, including 14 studies that met a strict empirical definition of a medical world model. The field is organized around four capabilities: patient state representation, temporal dynamics modelling, intervention-conditioned simulation, and clinician-supervised planning. Evidence spans medical imaging, longitudinal electronic health records, treatment response modelling, physiological and multimodal state modelling, ultrasound and surgical interaction, and population and health-system simulation; clinical digital twins are treated as a cross-cutting integration framework. Studies provide early evidence of technical feasibility for trajectory forecasting and comparison of candidate interventions, but most remain retrospective, task-specific, or preclinical. We distinguish functional capability from clinical evidence maturity and specify evidence needed to support progressively stronger clinical claims, from temporal forecasting to intervention comparison and planning-oriented decision support. These requirements include precise intervention representations, robust causal and mechanistic grounding, calibrated trajectory-level uncertainty, safety-constrained planning, external validation, and prospective multicentre evaluation against clinically meaningful endpoints. This framework aims to distinguish technically plausible simulation from clinically supportable prediction and decision support.

cs.CV