Data pruning can substantially reduce training cost by removing examples that contribute little additional learning signal, but it has not been studied for DNA language-model pretraining. We introduce Sequence Pruning (SP), a dynamic pruning framework that removes genomic sequences as they become easy for the model to predict. SP uses per-sequence pretraining accuracy computed directly from the model's forward pass, requiring no separate scoring model or additional pass over the corpus. We evaluate SP across five pretraining settings spanning two corpora, three model families, and both MLM and CLM objectives, with downstream evaluation on five genomic benchmarks. SP reduces pretraining data processing by up to 96% while largely preserving downstream performance. At moderate savings, pruning improves performance by up to 1.2 MCC points over full-data pretraining; at the highest savings, pretraining uses only 4% of the baseline GPU hours with little performance loss. SP also outperforms the dynamic pruning methods InfoBatch and BPAS across most comparisons. Beyond accuracy, our framework supports alternative criteria such as perplexity and EL2N, although accuracy yields the strongest downstream performance at matched savings. These results show that genomic pretraining does not require repeatedly processing all available sequences and that dynamic sequence-level pruning can substantially improve its data and computational efficiency. Code is available at https://github.com/FaiasPromit/pruning-dna-sequence.
Wangshu Cai, Jun Zhou, Lei Wang, Mohammad Aminul Islam, Xu Han, Kuldip Paliwal
原文摘要
Hyperspectral videos provide rich spectral signatures for robust tracking under challenging conditions such as camouflage and low illumination. However, limited hyperspectral annotations and the large RGB-hyperspectral domain gap hinder the direct use of modern temporally pretrained RGB trackers. We propose SProTrack, a multimodal framework that transfers temporal knowledge from pretrained RGB trackers to the hyperspectral domain through latent spectral prompting. The key idea is to decouple temporal modeling from spectral adaptation, allowing temporal dynamics to be inherited from RGB foundation models while hyperspectral information is learned from unlabeled data in a self-supervised manner. Unlike band-selection methods that discard most spectral information or prompt-based approaches that rely on local-search crops, SProTrack learns a global, scene-level spectral representation from the full hyperspectral frame using an autoencoder. This latent representation is used to guide spectral prompt extraction while a pretrained RGB tracker preserves strong temporal modeling on RGB-compatible inputs. By encoding spectral-spatial structure into compact latent prompts, SProTrack bridges the RGB-hyperspectral modality gap without extensive retraining or dense supervision. Experiments on HOT2020 and HOT2023 demonstrate that SProTrack achieves the best overall performance, with strong results across all spectral domains.