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版本更新 · v3arXiv:2609.35107

DoAtlas-2: A Foundation for Self-Evolving Causal Biomedical Discovery

Yulong Li, Rong Xia, Yuxuan Zhang, Jianxu Chen, Xiwei Liu, Haochen Xue, Maosheng Li, Yuhang Liu 等 15 位作者

We introduce DoAtlas-2, a foundation for self-evolving causal biomedical discovery that organizes knowledge around causal mechanisms and advances through external evidence from human populations. DoAtlas-2 integrates 771 research resources covering more than 720,000 participants in 48 countries, from longitudinal clinical phenotypes, medical imaging, and continuous physiological signals to eight molecular layers, together with an evidence network of approximately 4.7 million literature-derived records over 93,566 concepts and 149,383 candidate causal relations. DoAtlas-2 autonomously formulates research questions from evidence gaps and unresolved mechanisms, prespecifies their causal designs, and generates validated analyses. Supporting, challenging, and unresolved results continuously revise mechanistic interpretations, the causal evidence state, and the discovery frontier, so that DoAtlas-2 self-evolves within a closed loop of hypothesis generation, empirical testing, and renewed discovery. DoAtlas-2 has systematically evaluated 2,031 research questions. In the Human Phenotype Project (HPP), it formulated 4,014 candidate pathway questions across vascular, early-glycemic, and hepatic-metabolic systems, and screening of the first 1,079 yielded statistical support for 756. Representative studies identify blood pressure as a convergence node linking adiposity, hepatic, and lipid phenotypes to vascular outcomes, and show that an adiposity-inflammation-blood-pressure pathway is largely attenuated by joint adjustment for body mass index (BMI) and smoking. The discovered vascular network constitutes a completely interpretable predictive foundation, admitting exact attribution of every prediction and closed-form mediation effects. DoAtlas-2 thereby unifies causal mechanism discovery, population-evidence testing, and interpretable prediction within one continuously evolving foundation.

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cs.AI · q-bio.QM
arXiv ↗PDF ↗
版本更新 · v3arXiv:2510.15786

DexCanvas: Bridging Human Demonstrations and Robot Learning for Dexterous Manipulation

Xinyue Xu, Jieqiang Sun, Jing, Dai, Siyuan Chen, Lanjie Ma, Ke Sun, Bin Zhao 等 12 位作者

A dexterous hand succeeds or fails through contact, yet every scalable record of human manipulation (video, vision-based hand tracking, motion capture) observes how the hand moves and misses how it pushes. We present DexCanvas, a hybrid real-synthetic dataset of 7,000 hours of dexterous hand-object interaction with per-frame contact points and contact forces, grown from 70 hours of optical motion capture that spans 21 manipulation types, from power and precision grasps to in-hand manipulation. The forces come from a real-to-sim pipeline: one reinforcement learning (RL) policy, conditioned on object geometry and manipulation type, drives an actuated MANO hand in physics simulation to reproduce each captured object trajectory, and the simulator measures the contacts that produce the reproduced motion. The policy reproduces 87.5% of the demonstrations and still succeeds on 80.9% of rollouts from perturbed initial object poses; these perturbed rollouts expand the 70 captured hours a hundredfold. On six YCB objects absent from the capture set it succeeds 72.5% of the time. The contact channels make better policies: a Diffusion Policy that observes DexCanvas contact features succeeds 82.2% of the time, against 67.5% without them, over 18,522 trials. Contact-driven retargeting carries the same demonstrations to two dexterous robot hands, where the RL stage again produces stable rollouts. A first release of 111,857 force-annotated trajectories is publicly available on Hugging Face.

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cs.RO · cs.LG
arXiv ↗PDF ↗
新论文 · v1arXiv:2611.03442

Subpolynomial-Query Proximal Sampling Beyond Log-Concavity

Wei Guo, Bo Yuan, Ye He, Jiaming Liang, Molei Tao, Yongxin Chen

We study the gradient query complexity of sampling from a density $π(x)\propto\mathrm{e}^{-V(x)}$ on $\mathbb{R}^d$, where $V$ has a $β$-Lipschitz gradient but need not be convex. Our approach uses the proximal sampler, which alternates Gaussian perturbation with sampling a position conditional on the noisy observation. We implement its observation chain using the high-order noisy conditional sampler of [OpenAI 2026], obtaining improved dimension dependence under functional inequalities. If $π$ satisfies a log-Sobolev inequality (LSI) with constant $α$, then for every fixed $ν>0$, there is a finite constant $C_ν$ depending only on $ν$ such that the algorithm returns a sample within total-variation distance $\varepsilon$ using at most $C_νκ(d+κ+\varepsilon^{-1}+\|\nabla V(x_0)\|^2/β)^ν$ queries, where $κ=β/α$ and $x_0$ is an arbitrary reference point for initialization. The analysis controls center-dependent local errors along exact proximal histories and removes the final observation noise by conditional decoding. Under a Poincaré inequality (PI), we obtain a corresponding guarantee from a warm start with a known bound on its Rényi divergence. An oracle lower bound shows that a stationary point alone, which suffices under LSI, is insufficient under PI.

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stat.ML · cs.CC · cs.LG · math.ST
arXiv ↗PDF ↗
版本更新 · v4arXiv:2606.13102

FTP-1: A Generalist Foundation Tactile Policy Across Tactile Sensors for Contact-Rich Manipulation

Chengbo Yuan, Zicheng Zhang, Mingjie Zhou, Wendi Chen, Yi Wang, Zhuoyang Liu, Dantong Niu, Shuo Wang 等 17 位作者

Despite the success of vision-based generalist robotic policies, existing tactile-based policies remain tied to fixed embodiments and sensor setups. This is because tactile signals are highly heterogeneous across hardware, making cross-sensor generalization difficult. We present FTP-1,the first generalist foundation tactile policy pretrained to acquire transferable tactile manipulation abilities across diverse sensors and embodiments. FTP-1 supports varied tactile inputs, including image-, array-, and state-based signals, by using heterogeneous encoders to project them into unified morphology-aware latent tokens that are jointly modeled by a shared tactile Transformer expert. Pretrained on around 3,000 hours of tactile manipulation data aggregated from 26 data sources, spanning human and robot demonstrations across 21 sensors, FTP-1 learns tactile skills that transfer beyond the sensors seen during pretraining. Across downstream finetuning experiments spanning 5 hardware configurations, FTP-1 improves contact-rich manipulation on seen sensor setups by +17.2% and, surprisingly, transfers to two previously unseen tactile-sensor setups, achieving a +31% gain in success rate. FTP-1 establishes the first unified foundation baseline for tactile manipulation, providing future tactile policies with a shared model-level starting point. Pretrained models, datasets, training code and more visualization at https://ftp1-policy.github.io.

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cs.RO
arXiv ↗PDF ↗
新论文 · v1arXiv:2610.35980

UnityBench-Mini3D: Evaluating LLM Agents for 3D Game Development in Unity

Yijun Zhou, Minghao Shao, Ke Zhang, Renkai Yuan, Hongbo Yuan, Bin Hu, Bozhao Qian, Hongxia Shen 等 23 位作者

Game development stresses coding agents in ways general software engineering does not: correctness depends on how engine APIs, serialized scene state, and runtime behavior interact, not on source code alone. Existing benchmarks mainly target platforms such as Godot and heavily rely on LLM judges or coarse task-level outcomes. We present UnityBench-Mini3D, a benchmark of 77 project-level Unity tasks organized around seven expert-defined skill categories rather than tutorials or genres, with three difficulty tiers. Each task pairs a complete Unity project with natural-language requirements and is evaluated using 1,178 held-out, human-authored milestone tests covering scene structure, component configuration, and runtime behavior. This in-engine evaluation provides deterministic partial credit, localizes failures, and distinguishes partial implementations from complete solutions without relying on subjective judges. Across 21 models and 9 coding harnesses, the average pass rate reaches 80.9% on easy tasks but falls to 35.2% on hard tasks, with just 57.7% overall. UnityBench-Mini3D provides a reproducible, diagnostic testbed distinguishing systems across difficulty levels.

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cs.SE · cs.AI · cs.LG
arXiv ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.236ACL Anthology · ACL 2026

PILOT: Planning via Internalized Latent Optimization Trajectories for Large Language Models

Haoyu Zheng, Yun Zhu Shanghai Artificial Intelligence Laboratory, Yuqian Yuan Qwen Team and Zhejiang University, Bo Yuan, Wenqiao Zhang Zhejiang University, Siliang Tang Zhejiang University, Jun Xiao Zhejiang University

Strategic planning is critical for multi-step reasoning, yet compact Language Language Models (LLMs) often lack the capacity to formulate global strategies, leading to error propagation in long-horizon tasks. Our analysis reveals that LLMs possess latent reasoning capabilities that can be unlocked when conditioned on explicit plans from a teacher model; however, runtime reliance on external guidance is often impractical due to latency and availability constraints. To bridge this gap, we propose PILOT (Planning via Internalized Latent Optimization Trajectories), a non-invasive framework designed to internalize the strategic oversight of large models into intrinsic Latent Guidance. Instead of altering backbone weights, PILOT employs a lightweight Hyper-Network to synthesize a query-conditioned Latent Guidance. This vector acts as an internal steering mechanism, guiding the model’s representations toward optimal reasoning paths. Extensive experiments on mathematical and coding benchmarks demonstrate that PILOT effectively stabilizes reasoning trajectories, consistently outperforming strong baselines (e.g., +8.9% on MATH500) with negligible inference latency. Our code is available at: https://anonymous.4open.science/r/PILOT-B266

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.965ACL Anthology · ACL 2026

MoA: Heterogeneous Mixture of Adapters for Parameter-Efficient Fine-Tuning of Large Language Models

Jie Cao, Tianwei Lin, Bo Yuan, Rolan Yan, Hongyang He Manifolda.Ai, Wenqiao Zhang Zhejiang University, Juncheng Li Zhejiang University, Dongping Zhang China Jiliang University 等 10 位作者

Recent studies integrate Low-Rank Adaptation (LoRA) and Mixture-of-Experts (MoE) to further enhance the performance of parameter-efficient fine-tuning (PEFT) methods in Large Language Model (LLM) applications. Existing methods employ homogeneous MoE-LoRA architectures composed of LoRA experts with either similar or identical structures and capacities. However, these approaches often suffer from representation collapse and expert load imbalance, which negatively impact the potential of LLMs. To address these challenges, we propose a heterogeneous Mixture-of-Adapters (MoA) approach. This method dynamically integrates PEFT adapter experts with diverse structures, leveraging their complementary representational capabilities to foster expert specialization, thereby enhancing the effective transfer of pre-trained knowledge to downstream tasks. MoA supports two variants: (i) Soft MoA achieves fine-grained integration by performing a weighted fusion of all expert outputs; (ii) Sparse MoA activates adapter experts sparsely based on their contribution, achieving this with negligible performance degradation. Experimental results demonstrate that heterogeneous MoA outperforms homogeneous MoE-LoRA methods in both performance and parameter efficiency. Our project is available at https://github.com/DCDmllm/MoA.

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗