3D medical image classification is essential to modern clinical workflows. Medical foundation models (FMs) have emerged as a promising approach for scaling to new tasks, yet current research suffers from three critical pitfalls: data-regime bias, suboptimal adaptation, and insufficient task coverage. In this paper, we address these pitfalls and introduce AnyMC3D, a scalable 3D classifier adapted from 2D FMs. It allows efficient scaling to new tasks by adding only lightweight plugins ( 1M parameters per task) to a single frozen backbone. Besides, this versatile framework also supports multi-view inputs, auxiliary pixel-level supervision, and interpretable heatmap generation. We establish a comprehensive benchmark of 12 tasks covering diverse pathologies, anatomies, and modalities and systematically evaluate state-of-the-art 3D classification techniques. Our analysis reveals several key insights: (1) effective adaptation is critical to unlock FM potential, (2) general-purpose FMs can match medical-specific FMs if properly adapted, and (3) 2D-based methods surpass 3D architectures for 3D classification. For the first time, we demonstrate the feasibility of achieving state-of-the-art performance across diverse applications using a single scalable framework (e.g., 1st place in the *** challenge), eliminating the need for separate task-specific 3D models.
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cs.CV
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表
Voxel-wise dose prediction is a critical yet challenging task in radiotherapy (RT) planning, as bespoke models trained from scratch often struggle to generalize across institutions, scanners, and planning protocols. Meanwhile, large generative backbones pretrained on billion-scale visual data have learned strong geometric and structural priors that may transfer beyond their source domain. We propose DiffKT3D, an Any2Any 3D diffusion framework that transfers prior knowledge from pretrained video diffusion models to clinically meaningful dose prediction. To support flexible conditioning over heterogeneous clinical inputs, including CT, target and organ masks, body mask, and beam descriptors, we introduce a modality- and role-aware Any2Any formulation that avoids cross-attention while retaining a unified conditioning interface. We further apply reinforcement-learning (RL) post-training with a clinically informed Scorecard reward to align generations with institutional treatment preferences. On the GDP--HMM challenge, DiffKT3D reduces voxel-wise MAE from 2.07 to 1.93 relative to the top challenge solution, while also improving image quality and clinical preference alignment. These results show that pretrained diffusion priors, combined with flexible multimodal conditioning and scorecard-aligned post-training, provide an effective approach to RT dose prediction.
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cs.CV
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表