Kai Ma, Tianle Sun, Shun Zhou, Boyao Yang, Ningyu He, Haoyu Wang
Many decentralized exchanges use automated market makers (AMMs) to trade assets against liquidity pools. Modern AMMs allow third-party contracts, called Hooks, to customize this process. However, Hooks can impose additional deductions that fee breakdowns based on standard pool parameters do not itemize. We present, to the best of our knowledge, the first large-scale empirical study of the production Hook ecosystem, focusing on these undisclosed settlement charges. Our study covers 7,873 Hook deployments, 50,011 pools, and 296M pool events on Uniswap v4 and PancakeSwap Infinity across Ethereum and BNB Smart Chain (BSC) through August 1, 2026. We develop a bytecode analysis that reconstructs how Hooks change traders' payments and receipts, separating charges from exchanged assets and standard fees. We then reconstruct historical settlements to measure charging frequency and economic burden. We find that direct settlement adjustment is the dominant Hook capability, supported by 71.37% of registered Hooks. Charging capability is widespread and often exercised: 24.30% of Hooks can impose undisclosed deductions, and these deductions occur in 59.23% of accounted swaps involving such Hooks. These charges generate millions of dollars in revenue, with $3.97M recorded across Hooks with available token prices. These findings reveal a gap between standard fee displays and actual trading costs, motivating explicit disclosure of Hook deductions alongside standard fees.
GLP-1 medications are increasingly used for weight management, and many people share their experiences online. These narratives show why people take the drugs and what they experience, but they remain unstructured and disconnected from formal pharmacovigilance. We therefore present AskGLP1, a system that transforms online patient narratives into a knowledge graph (KG) and answers questions about medication experiences. Through an LLM-assisted pipeline grounded in the MedDRA terminology, AskGLP1 screens nearly 8.5 million Reddit posts for medication experiences and distills 163,135 of them, with 2,506 WebMD reviews, into a KG of 385,790 drug-side-effect and drug-purpose relations. We find that GLP-1 experiences are source- and drug-specific. Online narratives share the most common gastrointestinal symptoms with FAERS, but they foreground everyday burdens such as fatigue and food aversion, whereas FAERS reports more often include injection-site reactions and selected serious diagnoses such as pancreatitis. We further find that posts report less nausea and vomiting for tirzepatide than for semaglutide, more fatigue for Wegovy than Ozempic and for Zepbound than Mounjaro. Evaluations show that the agent answers with verifiable evidence and declines requests for medical advice. Our findings reveal gaps between what FAERS captures and what people report online, and they call for patient-centered approaches to pharmacovigilance. Code, prompts, and evaluation questions are available at https://github.com/ZhaoqianXue/AskGLP1.
ZhiYan Hou, Haiyun Guo Institute of automation, Chinese Academy of Sciences and University of the Chinese Academy of Sciences, Haokai Ma National University of Singapore, Yandu Sun Southeast University, Yonghui Yang National University of Singapore, Jinqiao Wang University of the Chinese Academy of Sciences, Wuhan AI Research and Institute of Automation, Chinese Academy of Sciences
Continual instruction tuning (CIT) requires multimodal large language models (MLLMs) to adapt to a stream of tasks without forgetting prior capabilities. A common strategy is to isolate updates by routing inputs to different LoRA experts. However, existing LoRA-based Mixture-of-Experts (MoE) methods often jointly update the router and experts in an indiscriminate way, causing the router’s preferences to co-drift with experts’ adaptation pathways and gradually deviate from early-stage input–expert specialization. We term this as Misaligned Co-drift, which blurs expert responsibilities and exacerbates forgetting. To address this, we introduce the pathway activation subspace (PASs), a LoRA-induced subspace that reflects which low-rank pathway directions an input activates in each expert, providing a capability-aligned coordinate system for routing and preservation. Based on PASs, we propose a fixed-capacity PASs-based MoE–LoRA method with two components: PAS-guided Reweighting, which calibrates routing using each expert’s pathway activation signals, and PAS-aware Rank Stabilization, which selectively stabilizes rank directions important to previous tasks. Experiments on a CIT benchmark show that our approach consistently outperforms a range of conventional continual learning baselines and MoE–LoRA variants in both accuracy and resistance to forgetting, without increasing model parameters. Our code is publicly available at https://github.com/yueluoshuangtian/PASs-MoE.
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表