Haokai Ma, Aoqi Hu, Yueao Xing, Ruobing Xie, Yonghui Yang, Teng Tu, Lei Meng, Tat-Seng Chua
Generative recommendation autoregressively generates the semantic IDs of the target item, unifying preference modeling and index retrieval within the shared token space. Recent attempts have introduced Multi-Token Prediction (MTP) into this field, yet they primarily inherit its efficiency merit, leaving its potential as dense supervision unexplored. Unlocking this potential hinges on whether future behaviors qualify as informative supervision. Our analysis reveals that future behaviors carry a semantic echo of the current one far above that of random pairs, which nevertheless decays along horizons under intent transitions, making them informative yet order-dependent signals. Motivated by this, we propose EchoRec, which empowers MTP with cycle-consistent holistic preference alignment across multi-horizon for generative recommendation. It comprises two synergistic modules. Horizon-aware Preference Generation (HPG) sequentially chains lightweight auxiliary branches upon the base recommender, where each branch conditions on its predecessor to respect preference evolution. Verifiable Holistic-Preference Alignment (VHA) further consolidates them into the holistic preference and echoes it back through cycle-consistent projectors to suppress spurious alignment, with a theoretical guarantee that excludes the rank-collapse form of spurious alignment under an invertible round trip, enabling the holistic preference to be retained in the decoding representation. All auxiliary components serve as disposable scaffolding discarded at inference, introducing negligible online serving overhead. Extensive experiments on four datasets demonstrate the superiority of our EchoRec, together with its naturally acquired multi-item generation ability. Our code and datasets will be available upon acceptance.
GLP-1 medications are increasingly used for weight management, and many people share their experiences online. These narratives show why people take the drugs and what they experience, but they remain unstructured and disconnected from formal pharmacovigilance. We therefore present AskGLP1, a system that transforms online patient narratives into a knowledge graph (KG) and answers questions about medication experiences. Through an LLM-assisted pipeline grounded in the MedDRA terminology, AskGLP1 screens nearly 8.5 million Reddit posts for medication experiences and distills 163,135 of them, with 2,506 WebMD reviews, into a KG of 385,790 drug-side-effect and drug-purpose relations. We find that GLP-1 experiences are source- and drug-specific. Online narratives share the most common gastrointestinal symptoms with FAERS, but they foreground everyday burdens such as fatigue and food aversion, whereas FAERS reports more often include injection-site reactions and selected serious diagnoses such as pancreatitis. We further find that posts report less nausea and vomiting for tirzepatide than for semaglutide, more fatigue for Wegovy than Ozempic and for Zepbound than Mounjaro. Evaluations show that the agent answers with verifiable evidence and declines requests for medical advice. Our findings reveal gaps between what FAERS captures and what people report online, and they call for patient-centered approaches to pharmacovigilance. Code, prompts, and evaluation questions are available at https://github.com/ZhaoqianXue/AskGLP1.
ZhiYan Hou, Haiyun Guo Institute of automation, Chinese Academy of Sciences and University of the Chinese Academy of Sciences, Haokai Ma National University of Singapore, Yandu Sun Southeast University, Yonghui Yang National University of Singapore, Jinqiao Wang University of the Chinese Academy of Sciences, Wuhan AI Research and Institute of Automation, Chinese Academy of Sciences
Continual instruction tuning (CIT) requires multimodal large language models (MLLMs) to adapt to a stream of tasks without forgetting prior capabilities. A common strategy is to isolate updates by routing inputs to different LoRA experts. However, existing LoRA-based Mixture-of-Experts (MoE) methods often jointly update the router and experts in an indiscriminate way, causing the router’s preferences to co-drift with experts’ adaptation pathways and gradually deviate from early-stage input–expert specialization. We term this as Misaligned Co-drift, which blurs expert responsibilities and exacerbates forgetting. To address this, we introduce the pathway activation subspace (PASs), a LoRA-induced subspace that reflects which low-rank pathway directions an input activates in each expert, providing a capability-aligned coordinate system for routing and preservation. Based on PASs, we propose a fixed-capacity PASs-based MoE–LoRA method with two components: PAS-guided Reweighting, which calibrates routing using each expert’s pathway activation signals, and PAS-aware Rank Stabilization, which selectively stabilizes rank directions important to previous tasks. Experiments on a CIT benchmark show that our approach consistently outperforms a range of conventional continual learning baselines and MoE–LoRA variants in both accuracy and resistance to forgetting, without increasing model parameters. Our code is publicly available at https://github.com/yueluoshuangtian/PASs-MoE.
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表