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arXiv 最近完成扫描:等待完成 · 全站最近入库:2026-11-02 00:39各信源进度 →

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版本更新 · v2arXiv:2604.00058

GenoBERT: A Language Model for Accurate Genotype Imputation

Lei Huang, Chuan Qiu, Kuan-Jui Su, Anqi Liu, Yun Gong, Weiqiang Lin, Lindong Jiang, Chen Zhao 等 16 位作者

Genotype imputation enables dense variant coverage for genome-wide association and risk-prediction studies, yet conventional reference-panel methods remain limited by ancestry bias and reduced rare-variant accuracy. We present Genotype Bidirectional Encoder Representations from Transformers (GenoBERT), a transformer-based, reference-free framework that tokenizes phased genotypes and uses a self-attention mechanism to capture both short- and long-range linkage disequilibrium (LD) dependencies. Benchmarking on two independent datasets including the Louisiana Osteoporosis Study (LOS) and the 1000 Genomes Project (1KGP) across ancestry groups and multiple genotype missingness levels (5-50%) shows that GenoBERT achieves the highest overall accuracy compared to four baseline methods (Beagle5.4, SCDA, BiU-Net, and STICI). At practical sparsity levels (up to 25% missing), GenoBERT attains high overall imputation accuracy ($r^2 approx 0.98$) across datasets, and maintains robust performance ($r^2 > 0.90$) even at 50% missingness. Experimental results across different ancestries confirm consistent gains across datasets, with resilience to small sample sizes and weak LD. A 128-SNP (single-nucleotide polymorphism) context window (approximately 100 Kb) is validated through LD-decay analyses as sufficient to capture local correlation structures. By eliminating reference-panel dependence while preserving high accuracy, GenoBERT provides a scalable and robust solution for genotype imputation and a foundation for downstream genomic modeling.

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q-bio.GN · cs.AI · cs.LG
arXiv ↗PDF ↗
新论文 · v1arXiv:2610.37231

TaskBridge: Technical Report for SIGIR 2026 eCommerce Challenge

Zhiheng Fu, Yupeng Hu, Zixu Li, Zhiwei Chen, Qinlei Huang, Shaokun Wang, Han Liu, Fan Liu 等 10 位作者

The SIGIR 2026 eCommerce Challenge Query Reformulation Task evaluates the reformulation of task-oriented queries into expressions suitable for product retrieval, followed by BM25-based retrieval. These queries often imply product needs through activity-level semantics, creating a lexical gap with catalog descriptions. Systems must preserve task intent while adapting the number of reformulations to the Automatic and Interactive protocols. We propose TaskBridge, a catalog-anchored framework comprising Catalog Semantic Anchoring, Unified Five-Candidate Rewriting, and Protocol-Aware Selection. It grounds queries in catalog vocabulary, generates five complementary reformulations, and selects one query for Automatic retrieval or up to four for Interactive retrieval using BM25 scores, query-product reranking, and weighted Jaccard overlap. The selected queries are independently executed using BM25 to produce results in the required six-column format. Experiments demonstrate improved retrieval effectiveness, with multiple complementary queries providing additional gains in the Interactive setting. TaskBridge achieved first place in the SIGIR 2026 eCommerce Challenge.

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cs.IR
arXiv ↗PDF ↗
新论文 · v1arXiv:2610.34658

Live Adaptation of Dataflow Stream Processing for Hybrid Edge-Cloud Analytics

Yuanli Wang, Prateek Jain, Lei Huang, Le Xu, Vasiliki Kalavri

Dataflow streaming systems, like Apache Flink and Spark Streaming, are integral to modern business analytics, providing real-time insights across industries. However, for emerging hybrid edge-cloud analytics pipelines, neither processing everything in the cloud nor static edge offloading can reliably sustain the target rate under dynamic WAN conditions and limited edge resources. In this paper, we explore how these datacenter-centric platforms can be extended to support such hybrid analytics pipelines. Our goal is to maintain full transparency for user applications, while retaining built-in fault tolerance, out-of-order processing, and existing ecosystem integrations. Achieving this is challenging because existing dataflow engines assume homogeneous resources, rely on static task placement, and do not support adaptation under dynamic network and edge conditions. We introduce Sluice, an adaptive data stream processing system for hybrid clouds, compatible with dataflow streaming engines. Sluice's key contributions are: (i) an automatic query rewriter that decomposes applications into independent, fault-tolerant segments, and (ii) a live routing mechanism that shifts computations between edge and cloud without pausing execution while preserving event-time semantics. We implement Sluice on Apache Flink and evaluate it on a physical testbed with Raspberry Pi devices, as well as on a large simulated testbed of 100 VMs. Across five real-world applications, our results show that Sluice seamlessly shifts computations between edge and cloud, while consistently achieving higher throughput than baseline systems.

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cs.DC
arXiv ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.1250ACL Anthology · ACL 2026

Question Tells You Where the Answer Is: Intention-aware Long-Context KV Cache Compression

Liang Zhao, Xiaocheng Feng, Weihong Zhong Harbin Institute of Technology, Lei Huang, Kun Zhu, Baoxin Wang IFLYTEK CO.LTD., Dayong Wu, Guoping Hu IFLYTEK CO.LTD. 等 10 位作者

The increasing context window greatly extends the capabilities of large language models, but on the other hand, it incurs an unaffordable memory overhead and computational latency due to the increasing Key-Value (KV) cache size. Recent KV cache compression methods manage to reduce the cache size by dropping irrelevant KVs. However, these methods often fail to identify crucial KVs for generation while excluding others accurately, resulting in severe information loss. To address this gap, we propose IntentKV, an intention-aware KV cache eviction method that identifies and retains crucial KVs according to the attention distribution of intention, which semantically reflects the user’s goal and determines which part of the context is relevant. The consistency between the semantics and attention distribution is further substantiated through meticulously designed experiments. On this basis, IntentKV first distinguishes intention tokens from the vanilla context tokens based on their attention distribution distances. Then, the block-wise cumulative attention is calculated via aggregating the intention token attention. Finally, blocks that acquire high cumulative attention are picked and stored in KV cache. We evaluate our method across diverse long-context tasks and models. Results demonstrate that IntentKV can effectively maintain the model performance while reducing the KV cache size from 128K to 2K, leading to a 6.3x increase in decoding speed and 7.8x enhancement in memory efficiency compared to the default setting.

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.1672ACL Anthology · ACL 2026

Knowledge-driven Augmentation and Retrieval for Integrative Temporal Adaptation

Weisi Liu University of Memphis, Guangzeng Han University of Memphis, Xiaolei Huang University of Memphis

Time introduces fundamental challenges in model development and deployment: models are usually trained on historical data while deployed on future data where semantic distributions and domain knowledge may evolve. Unfortunately, existing studies either overlook temporal shifts or hardly capture rich shifting patterns of both semantic and knowledge. We develop Knowledge-driven Augmentation and Retrieval for Integrative Temporal Adaptation (KARITA) to capture diverse temporal shifts (e.g., uncertainty and feature shift), construct and integrate rich knowledge sources (e.g., medical ontology like MeSH), and leverage shifting insights for selecting-retrieval augmented learning. We evaluate KARITA on classification tasks across multiple domains, clinical, legal, and scientific corpora, demonstrating consistent improvements across all domain with temporal adaptation. Our results show that knowledge integration can be more critical and effective in temporal augmentation and learning.

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.45ACL Anthology · ACL 2026

What Makes Good Instruction-Tuning Data? An In-Context Learning Perspective

Guangzeng Han University of Memphis, Xiaolei Huang University of Memphis

Instruction-tuning datasets often contain substantial redundancy and low-quality samples, necessitating effective data selection methods. We propose an instruction data selection framework based on weighted in-context influence (wICI), which measures how effectively each candidate example reduces instruction-following difficulty for semantically related peers. Through systematic experiments, we address three key questions: what constitutes effective instruction tuning data from an in-context perspective, whether sample difficulty correlates with in-context influence, and how in-context influence translates to instruction tuning effectiveness. Experiments across multiple models and benchmarks demonstrate that our method consistently outperforms existing baselines under constrained data budgets, while empirically showing that sample difficulty negatively correlates with in-context influence.

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.897ACL Anthology · ACL 2026

Stratagem: Learning Transferable Reasoning via Trajectory-Modulated Game Self-Play

Xiachong Feng University of Hong Kong, Deyi Yin, Xiaocheng Feng, Yi Jiang, Libo Qin Central South University, Yangfan Ye Harbin Institute of Technology, Lei Huang, Weitao Ma Harbin Institute of Technology 等 12 位作者

Games offer a compelling paradigm for developing general reasoning capabilities in language models, as they naturally demand strategic planning, probabilistic inference, and adaptive decision-making. However, existing self-play approaches rely solely on terminal game outcomes, providing no mechanism to distinguish transferable reasoning patterns from game-specific heuristics. We present STRATAGEM, which addresses two fundamental barriers to reasoning transfer: domain specificity, where learned patterns remain anchored in game semantics, and contextual stasis, where static game contexts fail to cultivate progressive reasoning. STRATAGEM selectively reinforces trajectories exhibiting abstract, domain-agnostic reasoning through a Reasoning Transferability Coefficient, while incentivizing adaptive reasoning development via a Reasoning Evolution Reward. Experiments across mathematical reasoning, general reasoning, and code generation benchmarks demonstrate substantial improvements, with particularly strong gains on competition-level mathematics where multi-step reasoning is critical. Ablation studies and human evaluation confirm that both components contribute to transferable reasoning.

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.900ACL Anthology · ACL 2026

Fine-Mem: Fine-Grained Feedback Alignment for Long-Horizon Memory Management

Weitao Ma Harbin Institute of Technology, Xiaocheng Feng, Lei Huang, Xiachong Feng University of Hong Kong, Zhanyu Ma, Jun Xu Meituan, Jiuchong Gao, Jinghua Hao 等 10 位作者

Effective memory management is essential for large language model agents to navigate long-horizon tasks. Recent research has explored using Reinforcement Learning to develop specialized memory manager agents. However, existing approaches rely on final task performance as the primary reward, which results in severe reward sparsity and ineffective credit assignment, providing insufficient guidance for individual memory operations. To this end, we propose Fine-Mem, a unified framework designed for fine-grained feedback alignment. First, we introduce a Chunk-level Step Reward to provide immediate step-level supervision via auxiliary chunk-specific question answering tasks. Second, we devise Evidence-Anchored Reward Attribution to redistribute global rewards by anchoring credit to key memory operations, based on the specific memory items utilized as evidence in reasoning. Together, these components enable stable policy optimization and align local memory operations with the long-term utility of memory. Experiments on Memalpha and MemoryAgentBench demonstrate that Fine-Mem consistently outperforms strong baselines, achieving superior success rates across various sub-tasks. Further analysis reveals its adaptability and strong generalization capabilities across diverse model configurations and backbones

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗