Maroof Kousar, Jinsung Han, Mohit Chandra, Munmun De Choudhury, Yibo Hu
Large language models (LLMs) are increasingly used to answer everyday health questions online, including whether someone can take another dose of an over-the-counter (OTC) medication. Yet this common safety-relevant setting remains underexplored in medical QA. Answering these questions requires checking previous doses, timing, and product-specific dosing limits, while recognizing when important information is missing. We introduce DoseBench, a focused benchmark of 230 consumer-style acetaminophen and ibuprofen dosing questions with human-annotated YES, NO, and AMBIGUOUS labels, and evaluate eight LLMs with five responses per question. Overall accuracy ranges from 44.8% to 62.2%, while models incorrectly approve 14.0% to 60.5% of prohibited doses. Models with similar accuracy can therefore make very different dosing decisions. Additional analyses show that these failures are not easily fixed by giving models more guidance. Asking models to check dose, timing, and missing information makes them more cautious, while providing drug facts improves accuracy but can make them overlook missing information. These findings highlight a broader challenge in health QA: applying rules correctly and recognizing when information is missing.
Mohit Chandra, Siddharth Sriraman Georgia Institute of Technology, Harneet Singh Khanuja Georgia Institute of Technology, Yiqiao Jin, Munmun De Choudhury
Limited access to mental healthcare, extended wait times, and increasing capabilities of Large Language Models (LLMs) has led individuals to turn to LLMs for fulfilling their mental health needs. However, examining the multi-turn mental health conversation capabilities of LLMs remains under-explored. Existing evaluation frameworks typically focus on diagnostic accuracy and win-rates and often overlook alignment with patient-specific goals, values, and personalities required for meaningful conversations. To address this, we introduce MedAgent, a novel framework for synthetically generating realistic, multi-turn mental health sensemaking conversations and use it to create the Mental Health Sensemaking Dialogue (MHSD) dataset, comprising over 2,200 patient–LLM conversations. Additionally, we present MultiSenseEval, a holistic framework to evaluate the multi-turn conversation abilities of LLMs in healthcare settings using human-centric criteria. Our findings reveal that frontier reasoning models yield below-par performance for patient-centric communication and struggle at precise (“hard”) diagnostic capabilities with average accuracy of ~31%. Additionally, we observed variation in model performance based on patient’s persona and performance drop with increasing turns in the conversation. Our work provides a comprehensive synthetic data generation framework, a dataset and evaluation framework for assessing LLMs in multi-turn mental health conversations.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表