AI Cosmos Team, Jinfeng Zhou, Yuxuan Chen, Fangming Chang, Mingyu Su, Yifan Zhu, Yuan Wang, Bo Zhang 等 35 位作者
Large language models (LLMs) can improve task performance during learning, yet these gains do not necessarily reflect learners' ability to thereafter apply the knowledge and skills independently. We present AI Cosmos, an agentic infrastructure for situated learning that organizes learning around two complementary principles: scenario-based participation and cumulative assets of practice. AI Cosmos organizes learners and role-specialized agents within learning scenarios that integrate task-relevant knowledge and, when needed, executable workbenches. An asset-memory loop preserves the processes and outcomes of practice as reusable assets with explicit provenance and dependencies. We evaluate scenario-based interaction through two preregistered randomized controlled studies examining the acquisition of legal reasoning and programming competence, holding the same underlying LLM across conditions. AI Cosmos achieves greater learning gains than a conventional LLM in legal reasoning and higher mastery of unseen programming problems than an LLM-as-Teacher baseline.
Haochen Xue, Anastasia Godneva, Yulong Li, Qi Cao, Zhaodong Wu, Kaiyu Liang, Jionglong Su, Eran Segal 等 9 位作者
Existing gut microbiome foundation models typically use flat taxon representations, limiting their ability to exploit known taxonomic hierarchies. We introduce TaxoMFM, a microbiome foundation model that integrates taxonomic structure into self-supervised learning. TaxoMFM jointly learns abundance patterns across taxonomic ranks and relative proportions within groups through taxonomy-aware encoding and hierarchical compositional reconstruction. We further construct TaxoGut-HPP, comprising 100,806 gut microbiome profiles from 231 source cohorts and covering 40 classification and 8 regression tasks. TaxoMFM achieves competitive performance across disease, gut health, host trait, and liver ultrasound phenotype prediction. In cross-cohort zero-shot transfer, where target cohorts are excluded from both pretraining and downstream adaptation, TaxoMFM achieves AUROCs of 0.838, 0.736, and 0.722 for colorectal cancer, type 2 diabetes, and inflammatory bowel disease, respectively. Further analyses show that TaxoMFM recovers community changes across taxonomic scales, while preserving community information and producing consistent representations under database updates and species-vocabulary shifts. Our code is available at https://anonymous.4open.science/r/TaxoMFM-F16D/.