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As one of the most important underwater sensing technologies, forward-looking sonar exhibits unique imaging characteristics. Sonar images are often affected by severe speckle noise, low texture contrast, acoustic shadows, and geometric distortions. These factors make it difficult for traditional teacher-student frameworks to achieve satisfactory performance in sonar semantic segmentation tasks under extremely limited labeled data conditions. To address this issue, we propose a Collaborative Teacher Semantic Segmentation Framework for forward-looking sonar images. This framework introduces a multi-teacher collaborative mechanism composed of one general teacher and multiple sonar-specific teachers. By adopting a multi-teacher alternating guidance strategy, the student model can learn general semantic representations while simultaneously capturing the unique characteristics of sonar images, thereby achieving more comprehensive and robust feature modeling. Considering the challenges of sonar images, which can lead teachers to generate a large number of noisy pseudo-labels, we further design a cross-teacher reliability assessment mechanism. This mechanism dynamically quantifies the reliability of pseudo-labels by evaluating the consistency and stability of predictions across multiple views and multiple teachers, thereby mitigating the negative impact caused by noisy pseudo-labels. Notably, on the FLSMD dataset, when only 2% of the data is labeled, our method achieves a 5.08% improvement in mIoU compared to other state-of-the-art approaches.

Clinical genomic analysis requires experts to integrate evolving guidelines, databases, and computational evidence. As sequencing has become increasingly accessible, this complex and labor-intensive process has become a major bottleneck to the timely use of genomic information in clinical decision-making. To fill this gap, we developed ClinGeX, a large-language-model agent that composes 105 curated executable skills through task-specific retrieval and dependency-aware orchestration. On 223 temporally held-out benchmark cases, ClinGeX achieved 71.7\% macro-averaged task-level concordance with expert reference classifications, compared with 45.7\% for the strongest comparator. In a three-condition, counterbalanced human-AI collaboration study, 45 clinical genomic professionals assessed 135 clinically derived cases under routine (no AI assistance), DeepSeek-assisted and ClinGeX-assisted conditions. ClinGeX assistance increased raw case-level concordance across criterion-level variant analysis, genomic interpretation in rare disease and molecular oncology decision-making (51.1\%, 57.8\%, 64.4\% versus 15.6\%, 31.1\%, 20.0\% in comparator conditions) and reduced reported interpretation time in all scenarios. During an exploratory one-month real-world non-interventional assessment, 11 experienced professionals submitted feedback on 96 self-selected analysis episodes and reported frequent conclusion adoption and time savings. These findings support executable domain skills as a promising approach to augment specialist genomic interpretation.