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arXiv 最近完成扫描:2026-11-12 15:11 · 全站最近入库:2026-11-12 06:37各信源进度 →

统计口径与数据新鲜度

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版本更新 · v2arXiv:2610.15221

HarnessNet: Feedback-driven Hierarchical Joint Harness Evolution for Multi-agent Systems

Zhaoyuan Qiu, Sachith Seneviratne, Yu Xia, Saman Halgamuge

原文摘要

AI agents can evolve by using environment feedback to revise their harnesses, the software managing model inputs, tool use, memory, and execution, while keeping foundation models frozen. Existing studies focus on single agents, leaving joint harness evolution in multi-agent systems (MAS) underexplored. A single global optimizer faces growing context and workload as the system scales, while access restrictions may prevent sharing agent internals or system-wide feedback. We propose HarnessNet, a framework for hierarchical harness evolution in MAS. Its basic unit, Agentron, comprises an evolvable forward harness, a foundation model, and a local optimizer that can observe and modify only that harness. Agentrons form a layered graph through which environment feedback propagates backward, with upstream optimizers receiving node-specific feedback from the downstream layer. This decomposes joint harness evolution into smaller, coordinated tasks with separate contexts, reducing individual optimizers' context and workload while keeping access local. Optimizers need not access all agent trajectories or raw environment feedback. Experiments on AgentBench with multiple foundation models demonstrate the feasibility of training HarnessNet. Compared with a single global optimizer, HarnessNet achieves comparable performance gains while respecting local privacy and requiring fewer tokens and less time per optimizer call. A migration study shows that the evolved harnesses remain jointly effective after replacing the foundation models, suggesting transferability across models.

cs.AI

版本更新 · v2arXiv:2505.18183

FRAME-C: A knowledge-augmented deep learning pipeline for classifying multi-electrode array electrophysiological signals

Nisal Ranasinghe, Dzung Do-Ha, Chathura J. Gamage, Simon Maksour, Tamasha Malepathirana, Sachith Seneviratne, Lezanne Ooi, Saman Halgamuge

原文摘要

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motor neuron degeneration, with changes to neuronal excitability being an early phenotype for ALS identified in patients and animal models. Recent advancements in induced pluripotent stem cell (iPSC) technology have enabled the generation of human iPSC-derived neuronal cultures, which, when combined with multi-electrode array (MEA) electrophysiology, provide rich spatial and temporal electrophysiological data. Traditionally, MEA data is analyzed using handcrafted features based on potentially imperfect domain knowledge, which while useful may not fully capture all the relevant characteristics inherent in the MEA data. Machine learning, in particular deep learning has the potential to automatically learn relevant characteristics (features) from raw data, without solely relying on handcrafted feature extraction. However, handcrafted features remain critical for encoding domain knowledge and improving model interpretability, especially in scenarios with limited or noisy data, as is often the case in most experimental studies. This study introduces FRAME-C, a knowledge-augmented machine learning pipeline that combines domain knowledge, raw spike waveform data, and deep learning techniques to classify MEA signals and identify ALS-specific phenotypes. FRAME-C leverages deep learning to extract important features from spike waveforms, while also incorporating handcrafted features such as spike amplitude, inter-spike interval, and spike duration, thus preserving key spatial and temporal information. We validated FRAME-C on both simulated and real-world MEA data from human iPSC-derived neuronal cultures, demonstrating its superior performance compared to existing methods for MEA classification.

eess.SP · cs.LG