This paper explores whether large language models (LLMs) can design video coding tools, a highly challenging task due to the intricate algorithmic coupling of tool modifications. In particular, we present an empirical case study on the Planar mode, a long-standing intra prediction tool in video coding standards. Our experiments operate within a generation-and-evaluation loop, with the LLM generating new Planar predictors, encoder trials evaluating their coding performance, and the LLM re-generating refined implementations based on the evaluation feedback. We first examine directly replacing the default Planar mode in the Fraunhofer Versatile Video Encoder (VVenC) under its faster preset. Experimental results demonstrate that the LLM-generated mode can outperform the conventional Planar mode on this lightweight toolset, achieving 0.18% bitrate savings with 0.4% complexity overhead on the standard benchmark. We further extend our evaluation to the Enhanced Compression Model (ECM). Leveraging newly introduced directional Planar modes, we investigate two integration strategies: directly replacing them, and introducing the LLM-generated predictor as an additional prediction mode with new syntax elements. The empirical results suggest that both strategies can yield coding gains under a constrained low-resolution setting. Overall, this study offers preliminary evidence and practical insights, highlighting both the potential and open challenges of LLM-based coding tool design.
Yuhang Zhang, Keyan Ding Zhejiang University, Peilin Chen City University of Hong Kong, Han Liu City University of Hong Kong, Can Lin, Ruixi Chen, Shiqi Wang City University of Hong Kong, Qi Song University of Science and Technology of China
Enzyme–reaction retrieval is a fundamental problem in computational biology, underpinning enzyme characterization, reaction mechanism elucidation, and the rational design of metabolic pathways and biocatalysts. As a bidirectional task, it entails both enzyme-to-reaction and reaction-to-enzyme mapping. However, existing approaches suffer from poor generalization across tasks and distributions, with performance highly sensitive to dataset splits and substantial asymmetry between retrieval directions. To address these challenges, we present TIGER, a Text-Informed Generalized Enzyme-Reaction Retrieval framework that leverages protein-to-text generation models to distill textual semantic knowledge from enzyme sequences, providing a generalized representation that bridges enzymes and biochemical reactions. To ensure the quality and reliability of textual semantics, we design a Dynamic Gating Network that adaptively fuses text-derived knowledge with sequence features, enabling more consistent and informative enzyme representations, while a Structure-Shared Feature Projector aligns enzyme and reaction representations within a unified latent space. Extensive experiments demonstrate that, under bidirectional retrieval supervision, TIGER significantly outperforms state-of-the-art baselines across diverse distributions and exhibits strong robustness and transferability across tasks.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表