Prabhu Nithin Gollapudi, Andreas Maier, Franziska Mathis-Ullrich, Water Zhao, Jia Wang, Siming Bayer
In the context of multi-stage trajectory planning for robotic percutaneous liver interventions, identifying a kinematically feasible entry point remains a critical computational bottleneck. Existing methods rely on exhaustive inverse kinematics or randomized searches, incurring delays of 13 to 27 seconds per target and limiting real-time intraoperative adaptation. This paper introduces an Orientation-Based Reachability Map (ORM) that precomputes the kinematic feasibility of a 6 Degrees of Freedom (DoF) serial manipulator across 188,873 workspace positions and encodes orientation feasibility into a compact, indexed 83 MB map. A Just-In-Time (JIT) compiled runtime pipeline replaces live optimization with near-instantaneous array lookups. Experimental evaluation demonstrates a reduction in planning latency from 13.5-26.9 s to 0.289-0.349 s per target while maintaining high geometric fidelity, achieving a mean convex hull volume overlap ratio of 0.933 and a mean alpha-shape volume ratio of 0.976 relative to the baseline reachable point cloud. The proposed ORM framework enables sub-second entry point planning and provides an efficient computational framework for robotic needle insertion in percutaneous liver ablation.
Sheethal Bhat, Mahfuzur Rahman Chowdhury, Imam Ahmed Shaik, Rose Dawn Bharath, Siming Bayer, Andreas Maier
Individualized attribution estimates which functional networks drive a model prediction for a given subject and is often proposed as an interpretable resting-state fMRI (rs-fMRI) biomarker, but its test-retest reliability is rarely quantified. We evaluate per-subject network-ablation attribution for a frozen resting-state functional connectivity (FC) predictor (Schaefer-200 FC predicting MMSE/ADAS-Cog13) trained on N=875 subjects from the Alzheimer's Disease Neuroimaging Initiative (ADNI), using, and (iii) a subject-level permutation null. Split-half reliability is near-ceiling (Spearman p=0.948/0.950) but drops on scan-rescan (p=0.609/0.616). Under the mismatched-subject null, correlations remain substantial (p~0.46-0.47), indicating strong population-shared structure, yet matched pairs exceed this null (z~6.6-6.9, p<=10-4). Thus, in ADNI, individualized network attribution contains a modest but non-zero person-specific component atop a strong population-shared pattern. We recommend reporting scan-rescan reliability together with a permutation-null control, rather than within-session proxies alone, to avoid overstating individual specificity.