Machine unlearning aims to remove the influence of specific training data from a model while preserving its general utility. In vision, many approximate unlearning methods pursue this goal through degradation-based heuristics, such as loss maximization or random labeling. Yet making a model worse on forget samples is not the same as making it behave as if those examples had never been seen: these signals can be poorly conditioned, destabilize optimization, and harm generalization. We argue that approximate unlearning should instead prioritize distributional indistinguishability, aligning the model's predictive behavior on forget data with that on truly unseen data. Motivated by this principle, we propose Reference-Guided Unlearning (ReGUn), a vision unlearning framework that uses disjoint held-out data to construct a principled, class-conditioned reference distribution for distillation. Rather than explicitly degrading predictions on forget examples, ReGUn guides them toward non-member behavior through held-out supervision. Across multiple architectures, natural image datasets, and forget fractions, ReGUn consistently improves the forgetting-utility trade-off relative to standard approximate baselines while closely matching retrain-like membership inference behavior. As one instantiation of this principle, the results suggest that simple objectives designed around indistinguishability can provide an effective alternative to complex degradation-based unlearning procedures.
Structure is Supervision: Multiview Masked Autoencoders for Radiology
Sonia Laguna, Andrea Agostini, Alain Ryser, Samuel Ruiperez-Campillo, Irene Cannistraci, Moritz Vandenhirtz, Stephan Mandt, Nicolas Deperrois 等 12 位作者
AI 速览：提出MVMAE自监督框架，利用放射学检查的多视图结构进行跨视图对齐与掩码重建，并在低标签场景下通过报告文本辅助提升疾病分类性能。
Building robust medical machine learning systems requires pretraining strategies that exploit the intrinsic structure present in clinical data. We introduce Multiview Masked Autoencoder (MVMAE), a self-supervised framework that leverages the natural multi-view organization of radiology studies to learn view-invariant and disease-relevant representations. MVMAE combines masked image reconstruction with cross-view alignment, transforming clinical redundancy across projections into a powerful self-supervisory signal. We further extend this approach with MVMAE-V2T, which incorporates radiology reports as an auxiliary text-based learning signal to enhance semantic grounding while preserving fully vision-based inference. Evaluated on a downstream disease classification task on three large-scale public datasets, MIMIC-CXR, CheXpert, and PadChest, MVMAE consistently outperforms supervised and vision-language baselines. Furthermore, MVMAE-V2T provides additional gains, particularly in low-label regimes where structured textual supervision is most beneficial. Together, these results establish the importance of structural and textual supervision as complementary paths toward scalable, clinically grounded medical foundation models.
Sonia Laguna, Jorge da Silva Goncalves, Moritz Vandenhirtz, Alain Ryser, Irene Cannistraci, Julia E. Vogt
Machine unlearning for vision models is rapidly becoming a practical requirement, driven by privacy regulations, data errors, and the need to remove harmful or corrupted training images. Despite this, most existing approximate unlearning methods tackle the problem from a post-hoc perspective. They attempt to erase the influence of targeted samples through parameter updates that typically require access to the full training data. This creates a mismatch with real deployment scenarios where unlearning requests can be anticipated, revealing a fundamental limitation of post-hoc approaches. We motivate unlearning by design, a novel paradigm for approximate methods in which models are directly trained to support forgetting as an inherent architectural capability. We instantiate this idea with Machine UNlearning via KEY deletion (MUNKEY), a memory-augmented transformer that decouples instance-specific memorization from model weights. Here, unlearning corresponds to removing the instance-identifying key, enabling zero-shot forgetting without weight updates or access to the original samples or labels. Across natural image benchmarks, fine-grained visual recognition, and medical datasets, MUNKEY outperforms all post-hoc baselines. Our results establish that unlearning by design enables fast, deployment-oriented unlearning while preserving predictive performance.