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新论文 · v1arXiv:2611.01527

From Tool State to Scientific Action: Auditing Decision Provenance in Biomedical Research Agents

Xingyu Yi, Xinya Zhang, Yunshen Zhou, Haoyu Bao

A scientific agent can give the same verdict while reading and citing different evidence. BioAgent-DF tests this separation using paired reference and candidate values saved at the same scientific computation site. It restores or transplants those values at their original coordinates, then runs the agent on healthy hardware. Across eight SciFact batches, Qwen3.5-4B shows repeatable citation changes in three capture-claim combinations, and Gemma 3 4B IT shows repeatable read and citation changes in four. These seven combinations cover two claims. Full restoration recovers the reference evidence sets while verdicts remain unchanged. Verdict changes observed under the baseline prompt did not recur under the explicit-example prompt. Complementary tool and optimizer experiments distinguish recovery of numerical state, recovery of ranked lists, and restoration of an agent's visible history. These results show that an audit should track both the evidence an agent uses and its final answer. In hERG cardiac-safety assay allocation, silent numerical faults changed testing decisions while the fixed-budget shortlist kept the same number of compounds labeled as blockers. After the agent had used faulty values, restoring its earlier execution state and supplying certified scores recovered all 39 changed decisions, whereas replacing the prediction file recovered none; no incorrect action was committed. A streaming implementation of the arithmetic checks reduced the total time for forward execution and verification by 42.4% relative to the original FP64 implementation, with identical flags and recovery outputs.

尚无 AI 解读,展示原文摘要

cs.AI · cs.LG · q-bio.QM
arXiv ↗PDF ↗
新论文 · v1arXiv:2610.40556

以技能为中心的智能体推进临床基因组分析

Advancing Clinical Genomic Analysis with a Skill-Centred Agent

Qiaoyu Zheng, Weike Zhao, Yanjie Fan, Ye Cao, Mengqi Jiang, Xiao Zhou, Xiaoman Zhang, Pengcheng Qiu 等 13 位作者

AI 速览:作者提出基于大语言模型的智能体 ClinGeX,通过检索与依赖感知编排 105 个可执行技能来辅助临床基因组解读,并在基准与人类-AI 协作研究中报告了优于对照的表现。

Clinical genomic analysis requires experts to integrate evolving guidelines, databases, and computational evidence. As sequencing has become increasingly accessible, this complex and labor-intensive process has become a major bottleneck to the timely use of genomic information in clinical decision-making. To fill this gap, we developed ClinGeX, a large-language-model agent that composes 105 curated executable skills through task-specific retrieval and dependency-aware orchestration. On 223 temporally held-out benchmark cases, ClinGeX achieved 71.7\% macro-averaged task-level concordance with expert reference classifications, compared with 45.7\% for the strongest comparator. In a three-condition, counterbalanced human-AI collaboration study, 45 clinical genomic professionals assessed 135 clinically derived cases under routine (no AI assistance), DeepSeek-assisted and ClinGeX-assisted conditions. ClinGeX assistance increased raw case-level concordance across criterion-level variant analysis, genomic interpretation in rare disease and molecular oncology decision-making (51.1\%, 57.8\%, 64.4\% versus 15.6\%, 31.1\%, 20.0\% in comparator conditions) and reduced reported interpretation time in all scenarios. During an exploratory one-month real-world non-interventional assessment, 11 experienced professionals submitted feedback on 96 self-selected analysis episodes and reported frequent conclusion adoption and time savings. These findings support executable domain skills as a promising approach to augment specialist genomic interpretation.

cs.AI · q-bio.GN
arXiv ↗PDF ↗
新论文 · v1arXiv:2610.36785

OmniGlimpse: Asymmetric Identity Memory for Online Multi-View Tracking

Rangya Zhang, Jiaping Xiao, Yujing Shang, Yuhang Zhang, Mingsheng Li, Mir Feroskhan

Multi-view tracking extends visual coverage beyond a single camera, providing complementary observations when targets are occluded or leave the view. This raises a question: how can observations from different views be matched to the correct identities without offline scene-specific training or camera calibration? Progress toward this goal remains limited because many offline formulations assume such deployment-specific knowledge, while online adaptation can amplify association errors. We study this problem as online multi-view identity maintenance (OMIM): targets are initialized once per view, with no further identity labels provided after each initialization. To this end, we introduce OmniGlimpse, an asymmetric propose-verify framework that separates adaptive association from stable identity consolidation. At the representation level, short-term local and cross-view evidence is mapped into target-specific adaptive spaces to propose associations, whereas long-term identity distributions are maintained for verification in a canonical space defined by a frozen encoder. At the update level, short-term evidence may guide current associations, whereas, after bootstrapping, only verified observations may update persistent memory or drive adaptation. Under a unified target-specified evaluation protocol, OmniGlimpse improves over the best evaluated online baseline for each metric by 9.1 IDF1 and 22.1 CVIDF1 points on M3Track. The corresponding gains on MvMHAT are 20.3 and 26.2 points. Despite using no offline scene-specific training, it outperforms offline-trained references in IDF1 and remains competitive in cross-view association. These results support an approach to online identity maintenance that adapts to changing appearances while consolidating reliable evidence into stable identity anchors.

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cs.CV
arXiv ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.237ACL Anthology · ACL 2026

Miner: Mining Intrinsic Mastery for Data-Efficient RL in Large Reasoning Models

Shuyang Jiang, Yuhao Wang, Ya Zhang Shanghai Jiao Tong University, Yanfeng Wang Shanghai Jiao Tong University, Yu Wang Shanghai Jiao Tong University

Current critic-free RL methods for large reasoning models suffer from severe inefficiency when training on positive homogeneous prompts (where all rollouts are correct), resulting in waste of rollouts due to zero advantage estimates. We introduce a radically simple yet powerful solution to Mine intrinsic mastery (Miner), that repurposes the policy’s intrinsic uncertainty as a self-supervised reward signal, with no external supervision, auxiliary models, or additional inference cost. Our method pioneers two key innovations: (1) a token-level focal credit assignment mechanism that dynamically amplifies gradients on critical uncertain tokens while suppressing overconfident ones, and (2) adaptive advantage calibration to seamlessly integrate intrinsic and verifiable rewards. Evaluated across six reasoning benchmarks on Qwen3-4B and Qwen3-8B base models, Miner achieves state-of-the-art performance among the other four algorithms, yielding up to 4.58 absolute gains in Pass@1 and 6.66 gains in Pass@K compared to GRPO. Comparison with other methods targeted at exploration enhancement further discloses the superiority of the two newly proposed innovations. This demonstrates that latent uncertainty exploitation is both necessary and sufficient for efficient and scalable RL training of reasoning models. Code is available at https://github.com/pixas/Miner.

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cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

ACL Anthology · ACL 2026 ↗PDF ↗