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新论文 · v1arXiv:2611.17336

回到像素:将潜空间视频扩散模型提升至像素空间

Back to Pixels: Lifting Latent Video Diffusion into Pixel Space

Yanke Song, Shuo Chen, Chris Rockwell, Guande He, Nan Liu, Desai Xie, Tianpei Gu, Yong-Hyun Park 等 12 位作者

AI 速读 基于摘要

PixVid 将预训练的潜空间视频扩散模型改造为直接在像素空间逐帧生成视频,以缓解 VAE 时空压缩带来的分辨率、条件控制与交互性限制。

cs.CV

查看原文摘要

Frontier video generation models work in a VAE latent space that compresses video in both space and time. This compression made training tractable, but now limits high-resolution, controllable, and interactive generation -- doubling resolution quadruples token count, conditions apply to groups of frames rather than individual ones, and each response must wait for the rest of its multi-frame block. We present PixVid, a simple yet effective method that lifts a pretrained latent video model to directly generate every frame in pixel space. PixVid keeps the diffusion transformer and replaces the VAE decoder with a convolutional head that renders its outputs into pixels. We find that predicting clean video rather than velocity, together with a larger noise shift, is key to quality. Finetuned from Wan2.1-14B, PixVid is competitive with the latent baseline within $\sim 1.3$M training clips. Working framewise in pixels, it generates at $2\times$ higher resolution with the same per-frame token count, keeps depth-conditioned video editing aligned under fast motion, and responds to each action at the next frame. Project page: https://chenshuo20.github.io/PixVid/

新论文 · v1arXiv:2611.17334

拆解多模态视觉编码

Unbundling Multimodal Vision Encoding

Ellis Brown, Chris Hoang, Shengyi Qian, Shang-Wen Li, Mike Lewis, Marjan Ghazvininejad, Luke Zettlemoyer, Lucas Beyer 等 12 位作者

AI 速读 基于摘要

在统一数据与匹配总计算量的受控框架下,作者报告视觉先验并非必需,真正关键的是专用视觉容量,且该容量可置于多模态融合早期而非融合前。

cs.CV · cs.LG

查看原文摘要

How multimodal language models should encode visual input remains up for debate. Most models use a pretrained vision encoder, while some recent recipes train the encoder from scratch with the language model or remove it entirely. Vision encoders bundle together three design choices: a visual prior from upstream pretraining, dedicated vision capacity, and pre-fusion placement of that capacity (i.e., before the multimodal backbone). Because published models also differ in data, architecture, and compute, comparing them cannot isolate the effect of each choice. We disentangle these choices via a controlled framework where we pretrain all models from scratch on common data and compare them on visual question answering and language benchmarks at matched lifetime compute. We find that the visual prior is not necessary; an encoder trained jointly from scratch is on par with a pretrained one, without a separate training stage. What matters instead is dedicated vision capacity: an encoder-free model trails on visual understanding even when its backbone is enlarged by the encoder's parameter count. Yet that capacity need not precede multimodal fusion, as vision-only modules added in-fusion to early backbone layers perform comparably to a pre-fusion encoder and can lower time to first token. These results also hold across backbone sizes, when encoder pretraining is treated as free, and when starting from a pretrained language model. Overall, our findings favor dedicated vision capacity trained jointly with the backbone and placed early within it.

新论文 · v1arXiv:2611.17331

TTB:面向仅解码器视角合成模型高效渲染的测试时烘焙

TTB: Test-time Baking for Efficient Rendering of Decoder-only View Synthesis Models

Chin-Yang Lin, Ryo Hachiuma, Jaesung Choe, Min-Hung Chen, Yu-Chiang Frank Wang, Yen-Yu Lin, Wei-Chen Chiu, Yu-Lun Liu 等 9 位作者

AI 速读 基于摘要

提出测试时烘焙(TTB),将跨视角注意力中的全局场景信息学习并烘焙进轻量MLP,以提升仅解码器视角合成模型的渲染速度与质量。

cs.CV

查看原文摘要

Decoder-only Large View Synthesis Models (LVSMs) with KV-cache have recently achieved state-of-the-art quality by regressing novel views from neural networks without reconstructing 3D geometry, while Test-Time Training (TTT) layers save computation but sacrifice quality. We propose Test-Time Baking (TTB), a strategy that learns to bake global scene information from cross-view attention into a lightweight MLP, enabling fast and high-fidelity novel-view decoding. The first key is to repurpose the fast-weight MLP of TTT to learn the cross-view attention mapping explicitly from its input-output pairs, rather than replacing attention entirely, achieving the same rendering efficiency as TTT while delivering substantially higher quality. The second key addresses a modality misalignment between context prefilling and novel-view rendering: we disentangle context tokens into camera-only context rendering tokens to serve as TTB input, and context ground-truth tokens with image content to serve as the TTB mapping target, ensuring the baked MLPs are relieved of the modality generalization challenge between context and novel-view processing. Our method achieves up to **23x** rendering speedup with quality on par with the state-of-the-art across several benchmarks. Project page: https://test-time-baking.github.io

新论文 · v1arXiv:2611.17330

ProtoVis-Nav:面向视觉-空间对齐无人机导航的原型视觉想象

ProtoVis-Nav: Prototypical Visual Imagination for Visual-Spatial Aligned UAV Navigation

Guangyuan Sui, Yunzhong Hou, Chi Harold Liu

AI 速读 基于摘要

提出原型视觉想象框架 ProtoVis-Nav,让无人机视觉语言导航模型先“想象”下一目标区域的局部视觉特征,再据此生成航点动作。

cs.RO · cs.CV

查看原文摘要

Vision language navigation (VLN) is very challenging for Unmanned Aerial Vehicles (UAVs) since small errors in 3D motion prediction can lead to navigation errors and collisions. Unable to fathom execution outcomes in 3D environments, existing methods often struggle to predict accurate navigation waypoints from language instructions. To solve this, we introduce the Prototypical Visual Imagination framework, shortened as ProtoVis-Nav, which forces the model to imagine an outcome-associated local visual representation for the intended next UAV movement. Specifically, we predict feature prototypes and use their linear combination to estimate the visual feature of the target region. In this manner, the VLN model first imagines the local visual representation of the next intended location, and then uses predicted prototypes as context for generating the final action, promoting alignment between visual context and waypoint outputs. Extensive experiments demonstrate the effectiveness of the ProtoVis-Nav framework and show substantial improvements over existing baselines.

新论文 · v1arXiv:2611.17318

Spatial Foundry:面向空间智能的多模态数据集

Spatial Foundry: A Multimodal Dataset for Spatial Intelligence

Ethan Lin, Yang Song

AI 速读 基于摘要

作者提出一个包含5,280个带家具住宅3D场景配置的多模态数据集,用共享场景坐标对齐视觉、几何与时间数据,以支持空间智能研究。

cs.CV

查看原文摘要

Spatial intelligence requires connecting visual observations to the geometry, objects, and persistent state of an environment. Images alone leave these relationships implicit, while disconnected annotations make it difficult to study appearance, camera motion, and scene changes under a common reference. We introduce Spatial Foundry, a collection of 5,280 furnished residential 3D scene configurations with editable assets and aligned visual, geometric, and temporal data. Its modalities include floor plans, perspective and panoramic RGB, metric depth, point clouds, meshes, instance-level 3D bounding boxes, and camera trajectories paired with video. Shared scene coordinates link observations across views and time; editable source scenes enable additional camera paths and controlled object changes. We describe the data representation and construction workflow, and discuss applications in floor-plan-conditioned 3D generation, geometric reconstruction, instance-level perception, camera-conditioned video generation, shared world modeling, and scene editing. Controlled camera and scene variations support spatial perception and world-model research. The public project page provides videos and an interactive colored point-cloud preview.

新论文 · v1arXiv:2611.17302

FLEX-LBP:面向纹理分类的精确二值推理局部二值模式学习

FLEX-LBP: Learning Local Binary Patterns with Exact Binary Inference for Texture Classification

Mohamed Alimoussa, Amal El Kaid

AI 速读 基于摘要

FLEX-LBP 通过反向传播学习 LBP 的半径、采样角度、颜色变换与阈值,前向仍计算精确二值编码与硬直方图计数,从而在推理成本不变的前提下提升纹理分类精度。

cs.CV · cs.LG

查看原文摘要

Local Binary Patterns (LBP) remain among the most widely used texture descriptors, from industrial inspection to medical imaging. Yet their radius, sampling angles, color transform and thresholds are fixed by hand for each dataset. We present FLEX-LBP, which learns these parameters by backpropagation while every forward pass computes exact binary codes and hard histogram counts. A straight-through estimator acts only in the backward pass, so the deployed descriptor is an interpretable hard-binary LBP with 90 learnable parameters and unchanged inference cost. In a controlled ablation on six color texture benchmarks, the component worth learning is dataset-dependent. One configuration, applied unchanged everywhere, learns the geometry and thresholds with the color transform frozen. It improves the nearest-neighbor accuracy of the identical fixed descriptor by 3.55 points on average over five seeds, significantly on five of six benchmarks and never significantly worse. With a linear discriminant readout, it gains 0.9 points; the fully learned descriptor gains 2.7 and has the highest mean. FLEX-LBP is more accurate than five classical LBP-family descriptors, PCANet and a neural LBP on five of six benchmarks. Its mean nearest-neighbor accuracy exceeds that of frozen ImageNet ResNet-50 features (23.5 million parameters). On the Kather colorectal cancer histology benchmark, the fully learned descriptor reaches 93.8%, significantly above the best classical descriptor (Completed LBP, 92.8%). The learned radii adapt in directions that recur across seeds. Noise drowns single-pixel comparisons and illuminant change flips inter-channel ones; median sampling or gray-world normalization restores 96-97%. The code is available as a drop-in PyTorch layer at https://github.com/medalimoussa/FLEX-LBP.

版本更新 · v3arXiv:2601.21419

扩散模型中预测目标的理解与学习

Understanding and Learning Prediction Targets in Diffusion Models

Qing Jin, Chaoyang Wang

AI 速读 基于摘要

该文提出广义预测形式 u=kx-(1-k)n 的理论框架,解释最优预测目标为何取决于数据几何,并提出从数据中学习参数 k 的 k-Diff 框架。

cs.LG · cs.CV

查看原文摘要

Recent advances in diffusion and flow matching models have highlighted a shift in the preferred prediction target -- moving from noise ($\varepsilon$) and velocity (v) to direct data (x) prediction -- particularly in high-dimensional settings. However, a formal explanation of why the optimal target depends on the specific properties of the data remains elusive. In this work, we provide a theoretical framework based on a generalized prediction formulation $u=kx-(1-k)n$, where $x$ represents clean data and $n$ denotes noise. This formulation accommodates arbitrary targets, of which $\varepsilon$-, v-, and x-prediction are special cases. We derive the analytical relationship between data's geometry and the optimal prediction target, offering a rigorous justification for why x-prediction becomes superior when the ambient dimension significantly exceeds the data's intrinsic dimension. Furthermore, our controlled analysis reveals how time conditioning and loss variations systematically modulate this optimal objective. While our theory identifies dimensionality as the governing factor for the optimal prediction target, the intrinsic dimension of manifold-bound data is typically intractable to estimate in practice. To bridge this gap, we propose k-Diff, a framework that employs a data-driven approach to learn the optimal prediction parameter k directly from data, bypassing the need for explicit dimension estimation. Extensive experiments in both latent-space and pixel-space image generation demonstrate that k-Diff consistently outperforms fixed-target baselines across varying architectures and data scales, providing a principled and automated approach to enhancing generative performance.

版本更新 · v2arXiv:2611.05843

双流:面向逆问题的图像-测量联合插值

Dual Flow: Joint Image-Measurement Interpolation for Inverse Problems

Sevket Ege Yesilyurt, Figen S. Oktem

AI 速读 基于摘要

提出 Dual Flow 联合流模型,在图像域与测量域耦合估计干净图像与无噪测量,从而求解线性逆问题。

eess.IV · cs.CV

查看原文摘要

Generative model-based approaches to linear inverse problems typically use the acquired noisy measurement to condition or guide sampling in the image domain. In this work, we introduce Dual Flow, a novel joint-flow model for solving linear inverse problems by jointly estimating the clean image and corresponding noise-free measurement from the observation. Specifically, Dual Flow formulates image reconstruction and measurement denoising as a coupled estimation problem, using coupled flows in the image and measurement domains. The acquired noisy measurement is used only to initialize the measurement state; thereafter, image and measurement states are jointly updated based on their current values. By construction, the final image and measurement estimates are guaranteed to satisfy the underlying forward model. We derive the sampling updates for the joint-flow which involves the conditional mean of the clean image given the joint state. We further derive a closed-form expression for a sufficient statistic of the joint state and show that the required conditional mean can be obtained by solving an image-domain Gaussian denoising problem involving operator-dependent, correlated noise. We train a velocity-prediction network using this formulation to estimate the conditional mean from the derived sufficient statistic. Extensive experiments across various linear inverse problems and image datasets demonstrate state-of-the-art performance in both distortion metrics and perceptual quality. Dual Flow requires no hyperparameter tuning beyond the number of inference steps and achieves shorter reconstruction times than competing methods. Additional analyses assess robustness to model mismatch, as well as the ability to generate diverse plausible reconstructions and characterize reconstruction uncertainty.

版本更新 · v5arXiv:2509.16806

MedGS:面向多模态三维医学成像的高斯泼溅

MedGS: Gaussian Splatting for Multi-Modal 3D Medical Imaging

Kacper Marzol, Ignacy Kolton, Weronika Smolak-Dyżewska, Joanna Kaleta, Żaneta Świderska-Chadaj, Marcin Mazur, Mirosław Dziekiewicz, Tomasz Markiewicz 等 9 位作者

AI 速读 基于摘要

MedGS 提出一种基于高斯泼溅的多任务框架,同时进行帧插值与分割,以从稀疏帧中实现高保真三维解剖重建。

cs.CV

查看原文摘要

Multi-modal three-dimensional (3D) medical imaging data, derived from ultrasound, magnetic resonance imaging (MRI), and computed tomography (CT), provide a widely adopted approach for non-invasive anatomical visualization. However, accurate modeling depends on surface reconstruction and frame-to-frame interpolation, where traditional methods often struggle with image noise and incomplete information between sparse frames. To address these challenges, we present \our{}, a novel framework based on Gaussian Splatting (GS) designed for high-fidelity 3D anatomical reconstruction. Uniquely, \our{} employs a multi-task architecture that simultaneously performs frame interpolation and segmentation using a unified geometric representation. By coupling these tasks, the model leverages dense signals from image synthesis to regularize the geometry, enabling high-quality surface extraction even from a limited number of input frames. Specifically, medical data are modeled as Folded-Gaussians with dual color attributes, supported by an In-Between Frame Regularization (IBFR) mechanism. Experimental results demonstrate that \our{} achieves higher metric scores than implicit neural representations and improves interpolation quality. Repository: https://github.com/gmum/MedGS

版本更新 · v2arXiv:2601.09606

GRCF:面向多模态情感分析的组级排序与校准框架

GRCF: Group-wise Ranking and Calibration Framework for Multimodal Sentiment Analysis

Manning Gao, Leheng Zhang, Shiqin Han, Haifeng Hu, Yuncheng Jiang, Sijie Mai

AI 速读 基于摘要

提出组级排序与校准框架GRCF,通过自适应误差加权与动态边距改进成对序数学习,兼顾相对序数结构与绝对分数校准。

cs.CV

查看原文摘要

Most multimodal sentiment analysis algorithms focus on point-wise regression. While straightforward, it uses absolute values to represent subjective sentiment and overlooks the ordinal nature of sentiment, resulting in unstable predictions and poor correlation. Inspired by the way humans perceive sentiment, pair-wise ordinal learning frameworks emerged to address this gap, capturing relative order by learning from comparisons. However, they have two limitations: First, they assign uniform importance to all pairs, failing to adaptively focus on hard-to-rank samples. Second, they employ static ranking margins, which fail to reflect the varying semantic distances between sentiment groups. To address this, we propose a Group-wise Ranking and Calibration Framework (GRCF) that introduces the Adaptive Error-weighting and Dynamic Margin mechanism, which resolves these limitations by simultaneously preserving the relative ordinal structure and ensuring absolute score calibration. Specifically, Stage 1 introduces a Group-aware Ranking Loss to build a fine-grained ordinal structure by assigning higher optimization priority to confusable pairs. Stage 2 then employs an MAE-driven objective to align the prediction magnitudes. To validate its generalizability, we extend GRCF to classification tasks, including Multimodal Humor and Sarcasm Detection. It achieves state-of-the-art performance on regression datasets while also showing strong generalizability in classification tasks.

新论文 · v1arXiv:2611.17194

eDMD:面向少步扩散蒸馏的端点分布匹配

eDMD: Endpoint Distribution Matching for Few-Step Diffusion Distillation

Tong Zhao, Xianfang Zeng, Yucheng Han, Ruoyu Wang, Mingkun Lei, Gang Yu, Chi Zhang

AI 速读 基于摘要

提出端点分布匹配蒸馏(eDMD),仅在学生最终输出上训练共享假模型以校正各去噪步,并配合精确教师监督,用于少步扩散模型蒸馏。

cs.CV

查看原文摘要

Distribution matching distillation (DMD) has emerged as a leading paradigm for distilling diffusion models into few-step students, where an auxiliary fake score model tracks the student's distribution and the discrepancy between the teacher and fake predictions drives the student toward the teacher. In multi-step distillation, although only the student's final output is delivered, existing methods train the fake model on intermediate states or across all denoising steps. Consequently, the student's update signal becomes entangled with intermediate distributions, which can distort the matching direction and remain nonzero even after the student's final outputs already match the teacher distribution. To resolve this mismatch, we propose Endpoint Distribution Matching Distillation (eDMD), which trains a single shared fake model exclusively on the student's final outputs and uses it to correct every denoising step. Our theoretical analysis proves that this endpoint reference guarantees that the distribution matching term vanishes if and only if the student's final output distribution matches the teacher's, regardless of intermediate distributions. Beyond the fake reference, we further strengthen teacher supervision through a precise teacher (PT) that replaces single-step guided predictions with short multi-step trajectories on the final noise interval, paired with a calibrated query density for intermediate steps. Experiments on SD3-Medium, FLUX.2-klein (4B and 9B), and Qwen-Image-2.1 demonstrate that eDMD consistently outperforms existing distribution matching methods for 4-step generation.

新论文 · v1arXiv:2611.17190

参考帧无人机视频稳定中的共识捕获:动态城市场景基准测试

Consensus Capture in Reference-Based UAV Video Stabilization: A Benchmark on Dynamic Urban Scenes

Robert Fonod, Nikolas Geroliminis

AI 速读 基于摘要

该论文提出一个两部分基准,用于测量参考帧无人机视频稳定中的“共识捕获”现象,并评估目标掩码能否防止该现象。

cs.CV

查看原文摘要

Reference-frame stabilization registers every frame of a hovering-drone video onto one reference frame, keeping object positions comparable. The registration pipelines it relies on are selected on feature-matching benchmarks in which only the camera moves. Over a busy intersection, vehicles moving together supply mutually consistent correspondences that can draw the robust homography estimate toward their motion: consensus capture, which inlier statistics cannot flag. A two-part benchmark measures it and the object masking meant to prevent it. A static protocol scores ten pipelines under exactly known homographies on 4K aerial frames, tuned on a site-disjoint split at a matched resolution and feature budget. A dynamic protocol scores them at an offline and a real-time budget on hovers selected from the video alone to span the amount and coherence of moving foreground, plus a stationary control. It measures background alignment, object position error and the share of a moving group's displacement an estimate follows, against a pseudo-ground-truth reference audited with manually annotated ground control points, which also score every candidate. On static scenes, tuned AKAZE, RootSIFT, SIFT and BRISK lead, retuning the matcher thresholds raises the mean average accuracy (mAA) by at most 0.0062, and masking costs less than 0.005. Unmasked ORB is captured on 28 of 304 real-time dynamic pairs and on 6 offline; its real-time captured estimates have a median corner error of 18.8 px yet typical inlier counts and ratios. Masking removes capture for every pipeline and leaves the leading pipelines unchanged. Code, data and results are released.

新论文 · v1arXiv:2611.17185

面向交互式与可微光照的神经渲染代理

Neural Render Proxies for Interactive and Differentiable Lighting

Sergio Sancho, Alexander Rath, Marco Manzi, Pascal Chang, Amit H. Bermano, Derek Nowrouzezahrai, Markus Gross, Marios Papas

AI 速读 基于摘要

作者提出一种神经渲染代理(NRP),通过将渲染解耦为路径采样与发光计算,实现固定相机与材质下静态场景的可交互、可微重光照。

cs.GR · cs.CV

查看原文摘要

Within the CG animation production pipeline, the challenges artists tackle in Lighting can be immense. Even minor adjustments require re-rendering massive scenes with slow offline renderers; global illumination has to be sampled and complex shaders have to be evaluated, leading to iteration times of minutes to hours per frame. To accelerate this process, we introduce a novel neural render proxy (NRP) that enables differentiable relighting of static scenes with fixed camera and materials at interactive rates. Our main insight is the decoupling of traditional rendering into path sampling and emission computation. From a single, light-agnostic render pass, we collect light transport data in the form of path samples. This enables rapidly sampling lighting conditions on the fly, and training a scene-specific lightweight neural network that learns how light is transported from any scene location to any image pixel. This approach is compatible with non-differentiable production renderers, induces minimal memory requirements during inference, and scales only with resolution and the number of light sources and parameters, but independently of scene and appearance complexity. Our evaluation demonstrates interactive frame rates for relighting (~30-60 Hz) while closely approximating the visual fidelity of ground-truth path tracing. In addition, the differentiable NRP enables fast, gradient-based inverse workflows, allowing artists to efficiently solve for lighting parameters from intuitive image-space edits or generative targets.

版本更新 · v2arXiv:2601.22275

VMonarch:基于结构化注意力的高效视频扩散Transformer

VMonarch: Efficient Video Diffusion Transformers with Structured Attention

Cheng Liang, Haoxian Chen, Liang Hou, Qi Fan, Gangshan Wu, Xin Tao, Limin Wang

AI 速读 基于摘要

作者提出VMonarch,用Monarch结构化矩阵表示视频DiT中的稀疏时空注意力,以降低注意力计算复杂度并加速长视频生成。

cs.CV · cs.AI

查看原文摘要

The quadratic complexity of the attention mechanism severely limits the context scalability of Video Diffusion Transformers (DiTs). We find that the highly sparse spatio-temporal attention patterns exhibited in Video DiTs can be naturally represented by the Monarch matrix. It is a class of structured matrices with flexible sparsity, enabling sub-quadratic attention via an alternating minimization algorithm. Accordingly, we propose VMonarch, a novel attention mechanism for Video DiTs that enables efficient computation over the dynamic sparse patterns with structured Monarch matrices. First, we adapt spatio-temporal Monarch factorization to explicitly capture the intra-frame and inter-frame correlations of the video data. Second, we introduce a recomputation strategy to mitigate artifacts arising from instabilities during alternating minimization of Monarch matrices. Third, we propose a novel online entropy algorithm fused into FlashAttention, enabling fast Monarch matrix updates for long sequences. Extensive experiments demonstrate that VMonarch achieves comparable or superior generation quality to full attention on VBench after minimal tuning. It overcomes the attention bottleneck in Video DiTs, reduces attention FLOPs by a factor of 17.5, and achieves a speedup of over 5x in attention computation for long videos, surpassing state-of-the-art sparse attention methods at 90% sparsity. Code is available at https://github.com/EricLina/VMonarch.

新论文 · v1arXiv:2611.17176

验证引导的提示选择用于差分变形攻击检测

Validation-Guided Prompt Selection for Differential Morphing Attack Detection

Raghavendra Ramachandra, Hailin Li

AI 速读 基于摘要

作者报告在冻结参数的视觉语言模型上,用带标签验证数据做提示选择可显著降低差分变形攻击检测的变形攻击分类错误率,但递归提示修订未超过初始选择。

cs.CV

查看原文摘要

Differential morphing attack detection (D-MAD) compares a trusted live capture with a document image that may contain a facial morph. We investigate whether labelled validation data can improve a frozen-parameter vision-language evaluator through prompt selection rather than model fine-tuning. Version~1 generates 50 candidate prompts and selects the top-ranked instruction using a security-oriented loss that prioritises missed morph attacks (MACER) while accounting for bona fide classification errors (BSCER), response failures, parse failures, and decision inconsistency. Version~2 recursively revises prompts using aggregate validation feedback. On a subject-disjoint test set of 160 pairs spanning LMA, MIPGAN-2, and PIPE, the selected Version~1 prompt achieves a (19.17\%) morph attack classification error rate (MACER), with (0.00\%) observed bona fide sample classification error rate (BSCER), compared with (70.00\%) MACER for a controlled manual prompt. The paired (50.83) percentage-point difference has a (95\%) subject-bootstrap interval of ([43.33,58.33]). Recursive revision does not surpass the best Generation~0 validation loss; the reported revised descendant obtains (31.67\%) test MACER. All 23 attacks missed by Version~1 are landmark-based (LMA) morphs. Overall, the results show that prompt formulation can substantially influence frozen-parameter VLM-based D-MAD performance, while also highlighting the challenge of recursive prompt refinement under a compact 10-subject validation setting.

新论文 · v1arXiv:2611.17172

SpotDiff:面向遥感影像零样本变化检测的即插即用框架

SpotDiff: A Plug-and-Play Framework for Zero-Shot Change Detection in Remote Sensing Imagery

Anit Upadhyaya, Ata Akbari Asanjan, Chaitanya Jalluri, Subash Yeggina, Jeremy Kravitz

AI 速读 基于摘要

SpotDiff 通过组合 DINOv3、AnyUp 与 SAM 3 等视觉基础模型,构建无需训练、无需变化标签的零样本遥感变化检测流程。

cs.CV

查看原文摘要

Remote sensing change detection usually relies on large collections of temporally aligned, pixel-level annotations, which limits its scalability across regions, imaging platforms and application domains. Recent zero-shot approaches reduce the need for supervision, but they often localize fine-grained changes poorly because their features are coarse or inconsistent across time. We present SpotDiff, a training-free, plug-and-play framework for zero-shot change detection built by composing complementary vision foundation models. SpotDiff uses DINOv3 for semantically robust features, AnyUp to reconstruct them at pixel resolution, and SAM 3 for text-guided region-of-interest proposals, which an inference-time multi-scale strategy (SWIMS) makes reliable on small objects. Change is then measured by comparing the reconstructed features of the two dates inside the proposed regions, with no learnable components, fine-tuning or change labels. To our knowledge, SpotDiff is the first change detection method to use a universal feature upsampler, which alone adds 13.8 F1 over bilinear upsampling of the same features. On LEVIR-CD, SpotDiff reaches 82.46 F1, 2.06 points above the strongest prior training-free method, and on the multi-class SECOND benchmark it improves building change detection by 10.3 IoU and the six-class average by 2.2 IoU. Qualitative results on PlanetScope (3 m) and Sentinel-2 (10 m) imagery show that the same pipeline transfers across resolutions without modification. Our results indicate that composing modern foundation models is an effective route to scalable, label-free change detection.

新论文 · v1arXiv:2611.17163

UAV-Flow++:面向语言引导无人机飞行的统一基准与学习套件

UAV-Flow++: A Unified Suite for Benchmarking and Learning Language-Guided UAV Flight

Donglin Yang, Xiangyu Wang, Yantong Zhong, Wenhao Zheng, Zihan Ding, Yue Liao, Hongsheng Li, Ke Xu 等 9 位作者

AI 速读 基于摘要

作者提出 Flying-on-a-Word(Flow)短程语言引导无人机飞行任务,并配套真实与仿真数据集、仿真评测环境及 FlowVLA 学习框架。

cs.RO · cs.CV

查看原文摘要

Language-guided UAV navigation has largely focused on long-horizon route planning, leaving short-range, object-relative flight maneuvers underexplored. To address this gap, we formulate Flying-on-a-Word (Flow), a task requiring a UAV to convert concise natural-language instruction, egocentric visual observation, and current state dynamics into continuous flight actions. Flow encompasses both primitive motion commands and complex object-interactive behaviors, assessing motion intent comprehension and spatial context grounding. To enable policy learning and closed-loop evaluation, we introduce UAV-Flow, a comprehensive dataset comprising 30,692 expert-piloted real-world trajectories across eight distinct motion categories, alongside 10,109 simulation trajectories in the UAV-Flow-Sim environment equipped with task-specific completion criteria. Furthermore, we develop FlowVLA, which undergoes imitation pretraining on mixed real-sim demonstrations and online post-training via Tail-Aware GRPO (TGRPO). By leveraging group reward distributions, TGRPO effectively reinforces high-reward action sequences. Evaluated on 273 held-out UAV-Flow-Sim episodes, pretrained FlowVLA achieves a mean success rate of 75.58%, outperforming the strongest baseline by 6.72 percentage points, which TGRPO post-training further elevates to 93.16% with superior sample efficiency. Physical UAV experiments demonstrate robust execution of object-relative commands in both indoor and outdoor real-world scenes. Together, Flow establishes a novel benchmark and learning framework for language-conditioned flight maneuvers.

新论文 · v1arXiv:2611.17146

HiVE-VQA:通过体嵌入实现分层交互的视频质量评估

HiVE-VQA: Hierarchical Interaction via Volumetric Embedding for Video Quality Assessment

Robbie Hamilton, Fan Zhang, David Bull

AI 速读 基于摘要

作者提出 HiVE-VQA,将冻结的 V-JEPA 2.1 视频编码器多层 token 网格堆叠为分层时空体,并用紧凑 3D 卷积头融合,用于无参考视频质量评估。

cs.CV

查看原文摘要

The proliferation of user-generated video content has made accurate and robust no-reference video quality assessment (NR-VQA) a highly important challenge. Existing research increasingly relies on architecturally complex multi-branch pipelines or computationally intensive fine-tuning of single-branch backbones. In this paper, we investigate whether a single frozen video foundation model can serve as an effective NR-VQA backbone, and propose HiVE-VQA, the first framework (to our knowledge) to apply a JEPA-based video encoder to this task. HiVE-VQA extracts token grids from multiple depths of a pre-trained V-JEPA 2.1 encoder and stacks them into a hierarchical spatio-temporal volume, which a compact 3D convolutional head fuses across its layer, spatial, and temporal axes, combining low-level distortion cues from shallow layers with the semantic and temporal context captured at greater depths. The encoder remains frozen throughout, so only the head is trained: 5.2M parameters (5.7\% of the total), with no auxiliary multi-modal models and an inference cost that is invariant to video resolution. Trained solely on LSVQ and evaluated without any fine-tuning, HiVE-VQA outperforms 17 state-of-the-art (SOTA) methods in SROCC and PLCC on both intra-dataset (LSVQ-test, LSVQ-1080p) and cross-dataset (KoNViD-1k, LIVE-VQC) benchmarks. These results indicate that hierarchical, depth-wise fusion of features from a single frozen video foundation model provides a more effective and efficient basis for NR-VQA than task-specific multi-network fusion. Code and model checkpoints are available at https://github.com/RobHam99/HiVE-VQA.

新论文 · v1arXiv:2611.17126

STeP-C:面向大规模分布式光纤传感的实时神经压缩

STeP-C: Real-Time Neural Compression for Distributed Fiber-Optic Sensing at Scale

Tingfeng Li, Ming-Fang Huang, Shaobo Han, Yue Tian

AI 速读 基于摘要

提出STeP-C神经压缩框架,在实时DAS采集系统上实现高压缩率、高吞吐的流式数据压缩。

cs.CV · cs.LG

查看原文摘要

Distributed fiber-optic sensing (DFOS) technologies such as Distributed Acoustic Sensing (DAS) generate continuous, high-resolution spatio-temporal data at rates exceeding hundreds of megabytes per second, creating severe challenges for real-time storage and transmission. While neural compression methods can achieve strong rate-distortion performance on sensing data, prior approaches either require per-segment retraining incompatible with streaming, or have only been validated offline. None have been demonstrated end-to-end on a continuously streaming DAS acquisition system at scale. We present STeP-C (Spatio-Temporal Predictive Compression), a neural compression framework that decouples spatial encoding, temporal prediction, and entropy-optimized residual coding, trained end-to-end with a rate-distortion objective motivated by conditional entropy reduction. Critically, we identify entropy coding as the dominant bottleneck for streaming deployment. We address it through GPU-side symbol computation, cached probability tables, and parallel GIL-free arithmetic coding, together with FP16 inference and batched entropy coding, enabling a full real-time pipeline built around a GPU ring buffer. We validate this pipeline on a live DAS testbed, achieving a 98.85% file size reduction at 31.04 dB full-band PSNR and an average throughput of 535 MB/s, exceeding the 324 MB/s requirement for 1 kHz, 81 km DAS streams. We further show that STeP-C substantially outperforms conventional codecs at practical streaming bitrates, can be applied to unseen channel ranges within the same acquisition system without retraining, and largely maintains downstream detector consistency, with 96.62% high-confidence class agreement and 100% Jaccard similarity on detected event types.

新论文 · v1arXiv:2611.17111

时空学习提升孔隙空间演化与流体驱替的量化

Spatiotemporal learning improves quantification of pore-space evolution and fluid displacement

Zhuangzhuang Ma, Rukuan Chai, Qianqian Ma, Yanghua Wang, Branko Bijeljic, Martin J. Blunt

AI 速读 基于摘要

提出基于Transformer的4D分割框架,利用时空信息从时间分辨微CT图像中更可靠地量化孔隙空间演化与流体驱替。

physics.flu-dyn · cs.CV

查看原文摘要

Pore-space evolution and fluid displacement influence how rocks transmit and store fluids, affecting geological carbon storage, underground hydrogen storage and groundwater contaminant transport. A single time-resolved micro-CT experiment may produce tens to hundreds of three-dimensional images, and segmentation is required to quantify physical properties and run image-based simulations. Traditional methods such as thresholding perform poorly on noisy, low-contrast images and need manual adjustment per image; 3D deep learning networks segment each image without temporal information, so their errors vary between images and could be mistaken for physical change. Here we introduce a transformer-based 4D segmentation framework combining spatial and temporal information. It uses sequential images to resolve ambiguous phase assignments and separate physical change from segmentation error. The method is tested on images of mineral dissolution: it measures pore-volume growth and rock boundaries more accurately than an equivalent 3D model that ignores temporal information. It also captures the increase in permeability verified against reference segmentations and flow simulations. The advantage transfers to another dissolution sample without retraining. On two other datasets of fluid displacement, it reduces spurious changes in predicted rock and porosity fluctuations and accurately identifies filling events. Spatiotemporal segmentation turns sequences of hundreds of three-dimensional images into more reliable quantitative measurements of pore-space evolution and fluid displacement without per-image parameter adjustment to support the analysis of time-resolved CT imaging.

新论文 · v1arXiv:2611.17105

从非人灵长类肝脏组织学预测乙醇饮用状态:面向少样本视觉-语言建模的参数高效微调概念验证

Predicting Ethanol Drinking Status from Nonhuman Primate Liver Histology: A Proof of Concept for Parameter-efficient Fine-tuning in Few-Shot Vision-Language Modeling

Amirmohammad Mohammadi, Rupak Khadka, Kathleen A. Grant, Mary Lauren Benton, Joshua Peeples

AI 速读 基于摘要

该概念验证研究评估视觉-语言模型结合参数高效微调(PEFT)在少样本全切片图像分类中预测非人灵长类乙醇饮用状态的效果。

cs.CV · cs.AI

查看原文摘要

Combining vision-language models (VLMs) with parameter-efficient fine-tuning (PEFT) offers a promising approach to few-shot whole-slide image (WSI) classification in computational pathology. This study evaluates this approach for predicting ethanol drinking status from nonhuman primate liver histology. Adapters are evaluated against non-PEFT configurations on a subset of the Monkey Alcohol Tissue Research Resource (MATRR). All evaluated PEFT configurations achieve higher mean balanced accuracy than the non-PEFT baselines. For example, in the four-shot setting, attention-based multiple instance learning (ABMIL) alone achieves 43.5% mean balanced accuracy, compared with 78.1% after adding an adapter. Qualitative attention analysis shows that textual pathway adaptations produce localized attention heatmaps, while visual pathway adaptations produce more diffuse ones. A pathologist's review identified similar histological features across adaptations.

新论文 · v1arXiv:2611.17104

TuMAP:一种双视角、形态型感知的病理组学流程,用于量化肾小管重塑

TuMAP: A Dual-View, Morphotype-Aware Pathomics Pipeline for Quantifying Renal Tubular Remodeling

Ruijie Wu, Yuechen Yang, Yanfan Zhu, Yu Wang, Shilin Zhao, Ming-Tsun Tsai, Szu-Yuan Li, Shuo-Ming Ou 等 11 位作者

AI 速读 基于摘要

作者提出 TuMAP 流程,结合双视角基础模型表征、形态型标注与患者级统计推断,从 PAS 染色肾活检切片中量化肾小管形态型组成及形态型内差异。

cs.CV · eess.IV

查看原文摘要

Quantifying disease-associated renal tubular remodeling is challenging because tubular appearances are heterogeneous. We introduce TuMAP (Tubular Morphotype-Aware Pathomics), a pipeline combining (1) dual-view foundation-model representations and provisional morphotype annotation, (2) compositional and within-morphotype pathomics, and (3) patient-level statistical inference. From 456,158 tubules in 358 PAS-stained kidney biopsy slides, TuMAP identified eight image-based morphotypes, seven of which showed stable subsampling assignments. Across 219 patients in six diagnostic groups, diabetic nephropathy (DN) and tubulointerstitial nephritis/acute tubular injury (TIN/ATI) each differed from minimal change disease in seven morphotype proportions, while IgA nephropathy differed in six. DN showed reduced nuclear solidity and increased eccentricity across all eight morphotypes. Area-normalized nuclear density exposed additional within-morphotype differences. TuMAP provides a framework for separating changes in tubular morphotype composition from phenotypic differences within morphotypes.

新论文 · v1arXiv:2611.17103

面向无数据模型合并的联合零空间投影

Joint Null-Space Projection for Data-Free Model Merging

Tian Xia

AI 速读 基于摘要

提出无需数据的闭式联合零空间投影(JNSP),通过去除各任务向量在其它任务输入子空间中的分量来缓解任务向量干扰,并在 CLIP 图像分类任务上报告了优于参数级免训练基线的合并精度。

cs.CV · cs.LG

查看原文摘要

Merging independently fine-tuned checkpoints into a single multi-task model requires no data, no labels, and no gradient steps. In practice the task vectors of different tasks interfere, and the standard remedies--averaging, magnitude pruning, sign election--operate entry by entry, ignoring that each delta induces a low-dimensional update on the hidden features it acts upon. We recast merging as a subspace interference problem. For every two-dimensional weight tensor we take the top-r right-singular subspace of each task's delta--the input directions along which that task moves the representation most--and remove from each task vector the component lying in the union of the other tasks' subspaces. The resulting Joint Null-Space Projection (JNSP) is closed-form and order-independent, needs no forward pass, and is defined entirely by the checkpoint set. On eight CLIP image-classification tasks JNSP merges ViT-B/16 experts to 89.45% average accuracy without using a single image, 11.88 points above the strongest parameter-wise training-free baseline (TIES-Merging, 77.57%), 14.22 above Task Arithmetic, and 0.98 above WUDI's data-free consensus merge (88.47%). The gain holds across three backbones on the independently trained TALL release (+10.8, +12.6, +9.1 over TIES for ViT-B/16, ViT-B/32, ViT-L/14) and replicates there at 89.20%; controls confirm the source--a single shared subspace instead of per-task ones loses 2.9 points, and a sequential variant collapses to 69.6%. On RoBERTa-large the same projection underperforms plain task arithmetic, which we report rather than hide. Code is available at https://github.com.

版本更新 · v3arXiv:2611.08577

美团机器人-0:面向桌面操作视觉-语言-动作基础模型

Meituan-Robotics-0: A Vision-Language-Action Foundation Model for Desktop Manipulation

Meituan Robotics Team, Caicheng Wang, Chen Zhao, Chengpeng Jin, Duo Xu, Fengjiao Chen, Guanglu Wan, Heqing Yang 等 38 位作者

AI 速读 基于摘要

MR0 是一个面向固定底座桌面操作的视觉-语言-动作基础模型与具身智能体系统,通过三阶段训练和 Rollback 数据机制实现跨本体控制与任务恢复。

cs.RO · cs.CV

查看原文摘要

We present Meituan-Robotics-0 (MR0), a vision-language-action foundation model and embodied-agent system for stationary-base desktop manipulation. MR0 combines 147 million vision-language samples with 15,060 hours of curated robot trajectories spanning 12 embodiments. A three-stage training recipe aligns multimodal representations with robot behavior through discrete action-token pre-training, transfers these priors to continuous cross-embodiment control through flow-matching mid-training, and adapts the policy through real-world post-training. We introduce Rollback, which pairs replaced policy segments with human corrections to provide positive and negative supervision for CFG-DAgger without value learning or advantage labeling. A unified end-effector interface supports heterogeneous embodiments, while asynchronous action-chunk merging maintains smooth execution under variable inference latency. An event-driven agent maintains persistent task events and reassesses plans when progress or feasibility changes, enabling cross-task retrieval and conditional task resumption. MR0 achieves 93.6% success on RoboTwin 2.0 and ranks fifth in the RoboDojo VLA track. Under matched HG-DAgger post-training, MR0 achieves higher average success rate and progress score than $π_{0.5}$ across three real-robot tasks. On Ethernet insertion, CFG-DAgger trained with Rollback data reaches 70% success and a progress score of 0.90. Qualitative agent deployments demonstrate cross-task event retrieval and recovery from temporarily unsatisfied task conditions.

新论文 · v1arXiv:2611.17077

SALT:面向遥感单时相跨数据集结构定位的状态对齐低秩迁移

SALT: State-Aligned Low-Rank Transfer for Single-Temporal Cross-Dataset Structural Localization in Remote Sensing

Aggelos Psiris, Georgios Angelidis, Giorgos Sfikas, Maria Vakalopoulou, Thomas Lagkas, Panagiotis Sarigiannidis, Georgios Th. Papadopoulos

AI 速读 基于摘要

SALT 提出一种状态对齐低秩迁移框架,在冻结 DINOv3 主干下学习正负结构状态,实现单时相跨数据集遥感结构定位。

cs.CV

查看原文摘要

Change detection in remote sensing conventionally relies on spatially aligned bi-temporal imagery, which may be unavailable or unreliable in practical scenarios. Recent single-temporal approaches address this limitation by learning structural evidence, such as building regions, from a labeled source dataset and transferring it to unseen target imagery using only the current image. However, adaptation to the source dataset can over-specialize pretrained features and reduce their cross-dataset generalization, a risk that this paper argues is higher when the feature adaptation is parameterized independently of the states used for prediction. To address this issue, the current study introduces SALT, a State-Aligned Low-Rank Transfer framework. SALT keeps a DINOv3 backbone frozen and learns negative and positive structural states that both score each patch and, through State-Aligned Low-Rank Adaptation (SALA), span the rank-2 subspace in which patch features are corrected. Directional State Alignment supervises these corrections to raise the evidence of positive patches and lower that of negative ones, while Geometry Preservation limits changes to the pairwise relations among pretrained patch features. Experiments on LEVIR-CD and the WHU aerial building dataset show that, at the pixel level and in both transfer directions, SALT outperforms four baselines reproduced under a common source-only protocol, improving over the strongest reproduced baselines by 9.45 and 5.79 points in pixel-level AP and by 27.69 and 14.25 points in IoU (LEVIR-CD to WHU and WHU to LEVIR-CD, respectively), with only 0.068M trainable parameters and 40.2 ms per image. In order to facilitate reproducibility and further research, the source code of SALT is available at https://github.com/gthpapadopoulos/SALT

新论文 · v1arXiv:2611.17060

Ropedia Xperience 2:面向物理AI环境与行为规模化扩展的黄金标准

Ropedia Xperience 2: A Gold Standard for Scaling Physical AI Environments and Behaviors

Hao Li, Fangzhou Hong, Zhaoxi Chen, Hui En Pang, Kairui Hu, Mingze Sun, Runmao Yao, Xinhao Ji 等 21 位作者

AI 速读 基于摘要

作者提出并发布一个联合采集真实环境三维扫描与人类行为示范的数据集,并展示如何将其转化为机器人学习可用的仿真环境与轨迹。

cs.CV

查看原文摘要

Large foundation models such as GPT-6 Astra and Claude Fable 5.1 have recently been shown to control robots directly from visual observations. They nevertheless remain brittle on long-horizon, contact-rich tasks in real-world environments. Further progress depends on two complementary resources: demonstrations of human behavior that supervise how tasks are performed, and interactive environments in which policies can be rolled out, evaluated, and improved in closed loop. Language models have advanced along well-characterized scaling laws; the corresponding question for physical AI is how capability scales with environments and behaviors, which first requires identifying which data to scale and how to produce and reuse such data continuously. To address this question, we introduce Ropedia Xperience 2, comprising 1,589 released metric-scale 3D scans and a collection of 4,230 egocentric recordings of 74 tasks (131 hours). We further show that each capture can be repurposed for robot learning: scenes are converted into physically interactive simulation environments, human motion is retargeted to whole-body robot trajectories, and additional robot behaviors are obtained through virtual teleoperation and automated long-horizon trajectory generation. We propose this joint capture of environments and behaviors as a gold standard for physical AI data collection, laying a data foundation for establishing scaling laws over environments and behaviors.

新论文 · v1arXiv:2611.17048

AURA 2.0:从用户驱动响应到流式视频中的模型主动对话

AURA 2.0: From User-Driven Responses to Model-Initiated Conversations in Streaming Video

Shuhan Li, Huankang Guan, Xintong Guo, Yang Bo, Yuyang He, Dunyuan Xu, Jingyan Chen, Fang Liu 等 18 位作者

AI 速读 基于摘要

AURA 2.0 是一个流式视频大语言模型,新增模型主动发起对话、流感知工具调用和交互式视觉定位三项能力,并配套专用数据集与三阶段训练方案。

cs.CV · cs.AI

查看原文摘要

Most AI assistants respond only when prompted, remaining silent even when events in the video stream offer meaningful opportunities for conversation. To move beyond purely user-driven interaction, we present AURA 2.0, a streaming video large language model that introduces three core upgrades to AURA. The key advance is Model-Initiated Conversation (MIC), which enables the model to identify topics worth discussing in the evolving visual stream and initiate conversations at appropriate moments without a user query. Stream-Aware Tool Calling (SATC) enables the model to invoke external tools using the current visual and conversational context and incorporate returned information into the ongoing interaction. Interactive Visual Grounding (IVG) supports visual grounding in both user inputs and model outputs. The model can identify objects marked by users on video frames and produce frame-aligned bounding boxes to link its responses to specific objects and regions. To develop these capabilities, we construct a dedicated streaming interaction dataset and adopt a three-stage training scheme to integrate the new behaviors with AURA's existing streaming interaction abilities. We further incorporate Long-Horizon Interaction Memory (LHIM) to maintain contextual continuity over extended video streams. Evaluations on public streaming benchmarks show that AURA 2.0 achieves leading performance among open-source streaming models, while targeted evaluations further validate its new interaction capabilities. We open-source the model weights and inference code.

新论文 · v1arXiv:2611.16984

ElasticDino: Dense Semantic Features Using Elastic Deformations

Ulysse Mizrahi, Sean Zaretzky, Dov Danon, Amit H. Bermano

原文摘要

Vision transformers (ViTs) serve as the backbone for countless vision tasks, including dense prediction tasks, such as segmentation and depth estimation, even though the quadratic complexity of self-attention severely limits feature resolution and induces spatial artifacts. In this work, we introduce ElasticDino, a lightweight adapter which produces high-resolution feature maps, adhering to the fine details of the input image. As a key insight, we observe the consistency of artifacts across channels, and simultaneously resolve them to match the input image structure. Using a slim architecture based on spatial deformations, ElasticDino produces pixel-aligned, high-resolution feature maps efficiently. Leveraging deformations allows strictly preserving sharp semantics, and thereby avoiding the smoothness biases inherent to alternative approaches. Due to the absence of ground truth, we employ pixel-level semantic segmentation and depth estimation with linear heads to predict a set of downstream dense tasks, guiding the deformation process without leaking task-specific semantics into the model. We demonstrate superior accuracy over current methods on a range of popular dense task benchmarks, with better computational performance.

cs.CV · cs.AI

版本更新 · v3arXiv:2111.13630

Efficient Multi-Organ Segmentation Using SpatialConfiguration-Net with Low GPU Memory Requirements

Franz Thaler, Christian Payer, Horst Bischof, Darko Stern

原文摘要

Even though many semantic segmentation methods exist that are able to perform well on many medical datasets, they are often not designed for direct use in clinical practice. The two main concerns are generalization to unseen data with a different visual appearance, e.g., images acquired using a different scanner, and efficiency in terms of computation time and required Graphics Processing Unit (GPU) memory. In this work, we employ a multi-organ segmentation model based on the SpatialConfiguration-Net (SCN), which integrates prior knowledge of the spatial configuration among the labelled organs to resolve spurious responses in the network outputs. Furthermore, we modified the architecture of the segmentation model to reduce its memory footprint as much as possible without drastically impacting the quality of the predictions. Lastly, we implemented a minimal inference script for which we optimized both execution time and required GPU memory.

eess.IV · cs.CV · cs.LG

新论文 · v1arXiv:2611.16955

A Disease-specific Retinal Aging Biomarker for Predicting Progression to Late Age-related Macular Degeneration

Hexin Dong, Benjamin Hou, Puzhen Wu, Mingquan Lin, Emily Y. Chew, Zhiyong Lu, Yifan Peng

原文摘要

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in older adults. While chronological age is a primary risk factor, it inadequately reflects individual variations in retinal aging, limiting effective AMD risk stratification and timely intervention. Here, we propose and validate fundus-based AMD age (FAA), which quantifies disease-specific retinal aging in AMD and captures accelerated AMD-related retinal aging, thereby improving prognostic precision over chronological age. Trained on 36,782 images from 2,192 participants in the Age-Related Eye Disease Study (AREDS) dataset and validated across AREDS and AREDS2 cohorts, our model demonstrates significant improvements over traditional chronological age-based approaches. Specifically, integrating the proposed FAA into Cox proportional-hazards models significantly enhances prediction performance. FAA improved the C-index from 0.836 to 0.888 and reduced the 5-year Brier score from 0.050 to 0.046 in AREDS, with consistent gains observed in AREDS2 (C-index 0.715 to 0.756; 2-year Brier 0.078 to 0.076). FAA showed improved prognostic performance across the two datasets and under different phenotype definitions (reading center-defined vs. specialist-defined grading), supporting its potential utility for AMD risk stratification. These findings highlight the advantage of incorporating FAA into AMD risk prediction frameworks, supporting further evaluation of FAA for AMD risk stratification.

cs.CV