论文库

原文摘要

Automatic cardiac motion tracking from cine cardiac magnetic resonance (CMR) imaging is essential for quantifying myocardial motion abnormalities associated with cardiovascular disease. Existing methods fall into two groups: those that represent motion without anatomical correspondence across subjects and therefore limit inter-subject motion assessment; and those that represent motion with globally corresponding points, which typically require a time-consuming and error-prone semi-automatic step to fit a cardiac atlas to the subject space. To address these limitations, this study proposes CardioDrift, a fully automatic, atlas-based probabilistic framework that represents subject-specific cardiac motion on a 3D atlas mesh with globally corresponding points. The Coherent Point Drift (CPD) formulation is generalised to jointly register the atlas surfaces of multiple cardiac regions to the anatomically corresponding contours extracted from cine CMR segmentation maps throughout the cardiac cycle. Slice-shift correction is embedded in the same probabilistic model, estimating slice-wise translations that suppress the misalignment artefact limiting atlas-fitting accuracy. Evaluation on 1301 randomly selected UK Biobank subjects and the M&M dataset, CardioDrift attains Dice similarity coefficients (DSCs) of $92.23\pm8.70\%$, $82.11\pm7.56\%$, and $88.69\pm4.13\%$ for the left ventricle (LV), myocardium (Myo), and right ventricle (RV), exceeding the strongest baseline on every distance and overlap metric of both datasets.