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Objective: Survival analysis is central to medical prediction, yet large language models (LLMs) are rarely used as end-to-end survival models because censoring prevents straightforward supervised fine-tuning. Here we present LLMSurvival, a framework that enables censoring-aware survival analysis with unmodified LLMs operating directly on tabular clinical data. Materials and Methods: LLMSurvival reformulates time-to-event prediction as pairwise ranking among comparable subjects, and derives test-time risk by aggregating comparisons against anchor individuals from the training cohort. Results: Across two clinical tasks (ICU mortality prediction in MIMIC-IV and fragility fracture prediction in a NewYork-Presbyterian/Weill Cornell Medicine cohort), LLMSurvival improves overall concordance over Cox proportional hazards modeling by 3.1% for ICU mortality and 0.5% for fracture risk, 2.1% on average for ICU mortality and 2.8% for fracture risk over three established deep learning survival models. Discussion: The results show that survival modeling with censoring can be made compatible with LLM fine-tuning through comparison-based reformulation. The framework demonstrates high portability and superior performance over expert curated scores like SAPS-II and FRAX scores across diverse clinical context. Furthermore, the framework supports local deployment, as compact, publicly available base models provide sufficient performance. Conclusion: The LLMSurvival framework serves as a proof of concept for an integrated, censoring-conscious approach to survival analysis via LLMs.

Recent Hypergraph-based retrieval-augmented generation (HyperRAG) methods use hyper edges to connect multiple entities simultaneously, enabling more efficient multi-entity evidence organization than pairwise graph structures. However, existing HyperRAG methods often rely on LLM-generated summaries to construct hyperedges, which can introduce hallucinations while also incurring high indexing costs. In addition, during retrieval, existing methods typically rely on either one-hop neighbor expansion or PageRank diffusion. The former may miss useful multi-hop evidence, while the latter can suffer from uncontrolled propagation over excessive hub nodes, leading to semantic drift and noisy reasoning chains. To address these challenges, we propose HyperSU, a novel hypergraph-based RAG framework featuring semantic-unit hyperedges and clue guided bidirectional retrieval. During construction, HyperSU formulates hyperedge construction as an entity-aware minimum-description length (MDL) optimization problem, inducing source-grounded semantic-unit hyperedges that balance sentence-level semantic coherence and entity compactness. It then constructs a hypergraph by modeling each semantic unit as a hyperedge over its co-mentioned entities. During retrieval, HyperSU performs clue-guided bidirectional expansion over the semantic-unit hypergraph, enabling both multi-hop evidence discovery and evidence-anchored noise reduction. Experiments show that HyperSU consistently improves answer accuracy over standard, graph-based, and hypergraph-based RAG baselines, raising average accuracy on GraphRAG Bench by 5.5 points over the strongest baseline (68.7 vs. 63.2), with larger gains on reasoning intensive tasks, where the relative improvement reaches 14.1%.

The tail trimming strategy is widely adopted for robustness against outlier contamination in statistical learning and operations research. However, it generally lacks the thorough understanding that to what extent the tail-trimming technique is effective for nonlinear regression. In this paper, we address the robust nonlinear regression based on the so-called interval conditional value-at-risk (In-CVaR), which is introduced to guard against outliers by trimming extreme losses. We first analyze the trimming effect of the In-CVaR based estimator under distributional perturbation. Our first finding is that the In-CVaR based estimator is qualitatively robust under distributional perturbation in terms of the Prokhorov metric if and only if the largest portion of losses is trimmed. Furthermore, under sample contamination, we derive a probably approximately correct (PAC) bound for the In-CVaR based estimator, showing that the preliminary covariate filtering that is customary in the literature is not needed for In-CVaR based regression. The nonconvexity of the In-CVaR objective, together with unboundedness of covariates, responses and parameter space create the technical challenges for our developed theory, and thus necessitate the new treatment of the qualitative robustness and PAC analysis. Overall, this study rigorously analyzes robustness properties of In-CVaR based nonlinear regression models, which illustrates to what extent the right tail-trimming of the loss by In-CVaR risk measure is essential and effective for robust nonlinear regression. These theoretical findings are further supported by numerical experiments.