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arXiv:2611.10789 · v1

Generating Diverse and Verified Synthetic Clinical Notes with Labels by Construction

首次提交 2026-11-07 23:14
版本更新 2026-11-07 23:14
雷达观测 2026-11-10 11:14
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摘要

Under strict privacy regulations in the clinical domain, de-identification is necessary to enable the use of clinical data such as for natural language processing. However, we currently lack sophisticated ways to tell which de-identification models actually are suitable. Specifically, we need benchmarks that are challenging, diverse, and clinically plausible, all while ensuring label correctness. To this end, we present SPARCLING, an LLM-based pipeline to generate synthetic discharge letters with character-exact PHI span annotations. Our pipeline combines structured attribute sampling, template generation, and red teaming to obtain diverse PHI-labeled discharge letters. In our experiments, we demonstrate this superior content diversity over existing public datasets. Further, we show SPARCLING's downstream utility as a benchmark to uncover failure modes of de-identifiers in the German clinical domain. Finally, our experiments show that training on our synthetic data can yield more capable de-identifiers than training on the scarce public data alone. Our code is available at https://github.com/Matt00n/phi_discharge_letter_generator.

作者备注:Accepted at the GenAI for Health Workshop @ NeurIPS 2026. 38 pages including appendix. Code: https://github.com/Matt00n/phi_discharge_letter_generator

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v1 · 2026-11-07 23:14 · 最新观测版本

Generating Diverse and Verified Synthetic Clinical Notes with Labels by Construction

Under strict privacy regulations in the clinical domain, de-identification is necessary to enable the use of clinical data such as for natural language processing. However, we currently lack sophisticated ways to tell which de-identification models actually are suitable. Specifically, we need benchmarks that are challenging, diverse, and clinically plausible, all while ensuring label correctness. To this end, we present SPARCLING, an LLM-based pipeline to generate synthetic discharge letters with character-exact PHI span annotations. Our pipeline combines structured attribute sampling, template generation, and red teaming to obtain diverse PHI-labeled discharge letters. In our experiments, we demonstrate this superior content diversity over existing public datasets. Further, we show SPARCLING's downstream utility as a benchmark to uncover failure modes of de-identifiers in the German clinical domain. Finally, our experiments show that training on our synthetic data can yield more capable de-identifiers than training on the scarce public data alone. Our code is available at https://github.com/Matt00n/phi_discharge_letter_generator.

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