← 研踪 PaperTrailCVF · CVPR 2026:cvf:da8932c705d35eb22d98b02f3b06cd34 · 记录 #1
Spatial-SAM: Spatially Consistent 3D Electron Microscopy Segmentation with SDF Memory and Semi-Supervised Learning
来源日期（仅到年份） 2026
来源记录日期 2026
雷达观测 2026-11-02 00:13
摘要
Segment Anything Model (SAM)-based approaches have shown strong potential for biomedical image segmentation. However, these methods often struggle to preserve spatial consistency in 3D electron microscopy (3D-EM) data and still require extensive manual annotation. We propose Spatial-SAM, a spatially consistent and annotation-efficient framework for high-precision 3D-EM segmentation. It introduces a 3D Signed Distance Field (SDF) memory mechanism that replaces SAM2's memory with SDF representations precomputed by a 3D U-Net, providing richer geometric information and improving spatial consistency. It also combines SAM2's few-shot capability with a dual-track pseudo-label iterative optimization strategy to learn large-scale 3D-EM segmentation from minimal annotations. Experiments show Spatial-SAM significantly outperforms existing semi-supervised methods and performs comparably to state-of-the-art fully supervised approaches on multiple 3D-EM benchmarks, reducing annotation costs while preserving spatial consistency. Code is available at https://github.com/Giluir/Spatial-SAM.
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记录 #1 · 2026 · 最新观测版本
Spatial-SAM: Spatially Consistent 3D Electron Microscopy Segmentation with SDF Memory and Semi-Supervised Learning
Segment Anything Model (SAM)-based approaches have shown strong potential for biomedical image segmentation. However, these methods often struggle to preserve spatial consistency in 3D electron microscopy (3D-EM) data and still require extensive manual annotation. We propose Spatial-SAM, a spatially consistent and annotation-efficient framework for high-precision 3D-EM segmentation. It introduces a 3D Signed Distance Field (SDF) memory mechanism that replaces SAM2's memory with SDF representations precomputed by a 3D U-Net, providing richer geometric information and improving spatial consistency. It also combines SAM2's few-shot capability with a dual-track pseudo-label iterative optimization strategy to learn large-scale 3D-EM segmentation from minimal annotations. Experiments show Spatial-SAM significantly outperforms existing semi-supervised methods and performs comparably to state-of-the-art fully supervised approaches on multiple 3D-EM benchmarks, reducing annotation costs while preserving spatial consistency. Code is available at https://github.com/Giluir/Spatial-SAM.
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