← 研踪 PaperTrailCVF · CVPR 2026:cvf:e42c02ccce24fa2cc0e73572fc6cf550 · 记录 #1
R2-Seg: Training-Free OOD Medical Tumor Segmentation via Anatomical Reasoning and Statistical Rejection
来源日期（仅到年份） 2026
来源记录日期 2026
雷达观测 2026-11-02 00:23
摘要
Foundation models for medical image segmentation struggle under out-of-distribution (OOD) shifts, often producing fragmented false positives on OOD tumors. We introduce **R^2-Seg**, a **training-free** framework for robust OOD tumor segmentation that operates via a two-stage **Reason-and-Reject** process. First, the **Reason** step employs an LLM-guided anatomical reasoning planner to localize organ anchors and generate multi-scale ROIs. Second, the **Reject** step applies two-sample statistical testing to candidates generated by a frozen foundation model (BiomedParse) within these ROIs. This statistical rejection filter retains only candidates significantly different from normal tissue, effectively suppressing false positives. Our framework requires no parameter updates, making it compatible with zero-update test-time augmentation and avoiding catastrophic forgetting. On multi-center and multi-modal tumor segmentation benchmarks, **R^2-Seg** substantially improves Dice, specificity, and sensitivity over strong baselines and the original foundation models.
论文发现出处
这些页面提供论文线索，不代表同行评审或质量认证。
观测到的版本
平台记录号代表本站观测到的元数据变化，不是作者修订号。来源日期仅到月份或年份时，按该月或该年首日存档。
记录 #1 · 2026 · 最新观测版本
R2-Seg: Training-Free OOD Medical Tumor Segmentation via Anatomical Reasoning and Statistical Rejection
Foundation models for medical image segmentation struggle under out-of-distribution (OOD) shifts, often producing fragmented false positives on OOD tumors. We introduce **R^2-Seg**, a **training-free** framework for robust OOD tumor segmentation that operates via a two-stage **Reason-and-Reject** process. First, the **Reason** step employs an LLM-guided anatomical reasoning planner to localize organ anchors and generate multi-scale ROIs. Second, the **Reject** step applies two-sample statistical testing to candidates generated by a frozen foundation model (BiomedParse) within these ROIs. This statistical rejection filter retains only candidates significantly different from normal tissue, effectively suppressing false positives. Our framework requires no parameter updates, making it compatible with zero-update test-time augmentation and avoiding catastrophic forgetting. On multi-center and multi-modal tumor segmentation benchmarks, **R^2-Seg** substantially improves Dice, specificity, and sensitivity over strong baselines and the original foundation models.
查看此版本解读 →查看此版本原文 ↗