← 研踪 PaperTrailCVF · CVPR 2026:cvf:eaefe516d2a72ad4f398ca72d4a53c52 · 记录 #1
Contrastive Cross-Bag Augmentation for Multiple Instance Learning-based Whole Slide Image Classification
来源日期（仅到年份） 2026
来源记录日期 2026
雷达观测 2026-11-05 00:51
摘要
Recent pseudo-bag augmentation methods for Multiple Instance Learning (MIL)-based Whole Slide Image (WSI) classification sample instances from a limited number of bags, resulting in constrained diversity. To address this issue, we propose Contrastive Cross-Bag Augmentation (C2Aug) to sample instances from all bags with the same class to increase the diversity of pseudo-bags. However, introducing new instances into the pseudo-bag increases the number of critical instances (e.g., tumor instances). This increase results in a reduced occurrence of pseudo-bags containing few critical instances, thereby limiting model performance, particularly on test slides with small tumor areas. To address this, we introduce a bag-level and group-level contrastive learning framework to enhance the discrimination of features with distinct semantic meanings, thereby improving model performance. C2Aug samples instances with consistent bag-level labels across the entire dataset, which simultaneously enhances the diversity of pseudo-bags and mitigates label noise. Experimental results demonstrate that C2Aug consistently outperforms state-of-the-art approaches across multiple evaluation metrics. Our code is publicly available at: https://github.com/weiaicunzai/mixup.
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记录 #1 · 2026 · 最新观测版本
Contrastive Cross-Bag Augmentation for Multiple Instance Learning-based Whole Slide Image Classification
Recent pseudo-bag augmentation methods for Multiple Instance Learning (MIL)-based Whole Slide Image (WSI) classification sample instances from a limited number of bags, resulting in constrained diversity. To address this issue, we propose Contrastive Cross-Bag Augmentation (C2Aug) to sample instances from all bags with the same class to increase the diversity of pseudo-bags. However, introducing new instances into the pseudo-bag increases the number of critical instances (e.g., tumor instances). This increase results in a reduced occurrence of pseudo-bags containing few critical instances, thereby limiting model performance, particularly on test slides with small tumor areas. To address this, we introduce a bag-level and group-level contrastive learning framework to enhance the discrimination of features with distinct semantic meanings, thereby improving model performance. C2Aug samples instances with consistent bag-level labels across the entire dataset, which simultaneously enhances the diversity of pseudo-bags and mitigates label noise. Experimental results demonstrate that C2Aug consistently outperforms state-of-the-art approaches across multiple evaluation metrics. Our code is publicly available at: https://github.com/weiaicunzai/mixup.
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