Nak-Jun Sung, Donghyun Lee, Bo Hwa Choi, Chae Jung Park
原文摘要
Mammography report generation is a critical yet underexplored task in medical AI, characterized by challenges such as multiview image reasoning, high-resolution visual cues, and unstructured radiologic language. In this work, we introduce AMRG (Automatic Mammography Report Generation), the first end-to-end framework for generating narrative mammography reports using large vision-language models (VLMs). Building upon MedGemma-4B-it-a domain-specialized, instruction-tuned VLM-we employ a parameter-efficient fine-tuning (PEFT) strategy via Low-Rank Adaptation (LoRA), enabling lightweight adaptation with minimal computational overhead. We train and evaluate AMRG on DMID, a publicly available dataset of paired high-resolution mammograms and diagnostic reports. This work establishes the first reproducible benchmark for mammography report generation, addressing a longstanding gap in multimodal clinical AI. We systematically explore LoRA hyperparameter configurations and conduct comparative experiments across multiple VLM backbones, including both domain-specific and general-purpose models under a unified tuning protocol. Our framework demonstrates strong performance across both language generation and clinical metrics, achieving a ROUGE-L score of 0.5691, METEOR of 0.6152, CIDEr of 0.5818, and BI-RADS accuracy of 0.5582. Qualitative analysis further highlights improved diagnostic consistency and reduced hallucinations. AMRG offers a scalable and adaptable foundation for radiology report generation and paves the way for future research in multimodal medical AI.
Recent work has demonstrated that imaging systems can be evaluated through the information content of their measurements alone, enabling application-agnostic optical design that avoids computational decoding challenges. Information-Driven Encoder Analysis Learning (IDEAL) was proposed to automate this process through gradient-based optimization. In this work, we study IDEAL across diverse imaging systems and find that it suffers from high memory usage, long runtimes, and a potentially mismatched objective function due to end-to-end differentiability requirements. We introduce IDEAL with Interchanging Optimization (IDEAL-IO), a method that decouples density estimation from optical parameter optimization by alternating between fitting models to current measurements and updating optical parameters using fixed models for information estimation. This approach reduces runtime and memory usage by up to 6x while enabling more expressive density models that guide optimization toward superior designs. We validate our method on diffractive optics, lensless imaging, and snapshot 3D microscopy applications, establishing information-theoretic optimization as a practical, scalable strategy for real-world imaging system design.