As an important research task of human cultural heritage, the restoration of artworks and calligraphy is of great significance. Seldom existing works have taken the multi-source (i.e., fragments are not ensured to be from the same piece of artworks) fragment-oriented restoration task into account. We propose ShreddingNet, a coarse-to-fine two-stage pipeline for multi-source manuscript restoration that operates without restrictive conditions. The proposed coarse stage compares the features of each fragment, selecting top-K candidates and clustering fragments by source. This design leverages the key insight that erroneous matches rarely cross source boundaries, enabling high-precision clustering. The proposed fine-grained stage evaluates candidates, yielding matching scores and filters out erroneous matching pairs from the candidate set; producing more precise final matching pairs for global assembly. Experiments conducted on more than 4,000 images from two datasets demonstrate the average reconstruction F1-score achieves 98.37%, which is 5.72% higher than the current state-of-the-art method, confirming the method's effectiveness and robustness. Source code is available at github.com/tqychy/shreddingnet.
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cs.CV
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表
Foundation models have achieved success in computational pathology, demonstrating generalization across histopathology tasks. However, existing models overlook the heterogeneous and non-uniform organization of regions of interest (ROIs) because they rely on natural image backbones not tailored for tissue morphology. Consequently, they fail to capture the coherent tissue architecture beyond patches, limiting interpretability and clinical relevance. To address these challenges, we present Cross-modal Adaptive Region Encoder (CARE), a foundation model for pathology that partitions WSIs into several morphologically relevant regions. Specifically, CARE employs a two-stage pretraining strategy: (1) a self-supervised unimodal pretraining stage that learns morphological representations from 34,277 whole-slide images (WSIs) without segmentation annotations, and (2) a cross-modal alignment stage that leverages RNA and protein profiles to refine the construction and representation of adaptive regions. This molecular guidance enables CARE to identify biologically relevant patterns and generate irregular yet coherent tissue regions, selecting the representative area as ROI. CARE supports a broad range of pathology-related tasks, using either the ROI feature or the slide-level feature obtained by aggregating adaptive regions. Based on only one-tenth of the pretraining data typically used by mainstream foundation models, CARE achieves superior average performance across 33 downstream benchmarks, including morphological classification, molecular prediction, and survival analysis, and outperforms other foundation model baselines overall.
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cs.CV
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition · 2026 · 正式发表