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版本更新 · v3arXiv:2511.09394

EyeAgent: An Agentic AI System for Multimodal Clinical Decision Support in Ophthalmology

Danli Shi, Xiaolan Chen, Bingjie Yan, Weiyi Zhang, Jiancheng Yang, Ruoyu Chen, Xinyuan Wu, Siyu Huang 等 26 位作者

原文摘要

Current medical artificial intelligence (AI) systems are often task-specific, poorly integrated, and difficult to interpret, limiting support for multimodal clinical workflows. We developed and evaluated EyeAgent for ophthalmic decision support. EyeAgent comprises three layers including 54 task-specific EyeTools, 32 clinical skills, and a modular large language model reasoning core with interchangeable backbones. A multi-level evaluation distinguished this scope from empirical system-level validation. Component-level evaluation assessed newly developed models on held-out splits of datasets totaling 871,862 samples. System-level evaluation included illustrative cases of workflow breadth, a 200-case expert-rating study of output quality, and an exploratory multicenter reader study comparing unassisted and EyeAgent-assisted performance among 27 ophthalmologists from 11 centers. Skill-level and backbone ablations further assessed orchestration and robustness. In illustrative cases, EyeAgent showed task-specific advantages over GPT-5.5 in lesion quantitation, cross-modality synthesis, and uncertainty-aware reporting. In the expert-rating study, EyeAgent achieved an F1 score of 0.84 for skill selection, with 82.7%-92.0% of outputs rated acceptable or better across six clinical dimensions. In the exploratory multicenter reader study, diagnostic accuracy increased from 72.8% unassisted to 91.9% assisted (difference, 19.1 percentage points (pp); 95% CI, 13.6-24.7; Holm-adjusted P<0.001). Report completeness increased from 55.8% to 75.6% (difference, 19.8 pp; 95% CI, 14.8-24.7; Holm-adjusted P<0.001). Across the evaluated settings, EyeAgent supported interpretable, evidence-guided reasoning and showed potential for human-AI collaboration. Broader real-world effectiveness and generalizability require prospective and cross-population validation.

cs.HC

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首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.1165ACL Anthology · ACL 2026

Towards Stable and Effective Reinforcement Learning for Mixture-of-Experts

Di Zhang, Xun Wu, Shaohan Huang, Lingjie Jiang Peking University, Yaru Hao Microsoft Research Asia, Li Dong Microsoft Research, Zewen Chi Microsoft Research, Zhifang Sui Peking University 等 9 位作者

原文摘要

Reinforcement learning with verifiable rewards (RLVR) has emerged as a powerful paradigm for improving reasoning capabilities. However, training RLVR with Mixture-of-Experts (MoE) policies remains fragile and is often prone to reward collapse.We identify a MoE-specific source of instability, referred to as router shift (RS), where changes in expert routing across policy updates exacerbate off-policy mismatch. This effect leads to increasingly volatile importance-ratio signals and bursty clipping behavior, which consistently precede training collapse.Motivated by this diagnosis, we propose Router-Shift Policy Optimization (RSPO). RSPO computes a per-token router-shift ratio conditioned on the previously activated experts, applies stop-gradient and a lower-bound floor, and softly rescales importance ratios prior to clipping and aggregation. This design explicitly accounts for routing-induced distributional drift during off-policy optimization.We evaluate the effect of RSPO under two settings: a synthetic countdown task and real-world reasoning tasks on MATH and Code. Across both settings, RSPO achieves better performance and exhibits greater stability compared to recent MoE-based RLVR methods.

cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

新论文 · v1arXiv:2306.07174Google Research

Augmenting Language Models with Long-Term Memory

Weizhi Wang, Li Dong, Hao Cheng, Xiaodong Liu, Xifeng Yan, Jianfeng Gao, Furu Wei

原文摘要

Existing large language models (LLMs) can only afford fix-sized inputs due to the input length limit, preventing them from utilizing rich long-context information from past inputs. To address this, we propose a framework, Language Models Augmented with Long-Term Memory (LongMem), which enables LLMs to memorize long history. We design a novel decoupled network architecture with the original backbone LLM frozen as a memory encoder and an adaptive residual side-network as a memory retriever and reader. Such a decoupled memory design can easily cache and update long-term past contexts for memory retrieval without suffering from memory staleness. Enhanced with memory-augmented adaptation training, LongMem can thus memorize long past context and use long-term memory for language modeling. The proposed memory retrieval module can handle unlimited-length context in its memory bank to benefit various downstream tasks. Typically, LongMem can enlarge the long-form memory to 65k tokens and thus cache many-shot extra demonstration examples as long-form memory for in-context learning. Experiments show that our method outperforms strong long-context models on ChapterBreak, a challenging long-context modeling benchmark, and achieves remarkable improvements on memory-augmented in-context learning over LLMs. The results demonstrate that the proposed method is effective in helping language models to memorize and utilize long-form contents. Our code is open-sourced at https://aka.ms/LongMem.

cs.CL

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