Diagnosis by Composition: Detecting and Localizing Unseen Diseases by Composing Learned Radiological Findings
Kaihua Hou, Wei Liu, Yi Huang, Hao Zhang, Haibo Jin, Yifei Sun, Yuan gao, Zuoou Li 等 13 位作者
AI 速览：提出诊断即组合（DbC）框架，通过学习放射学征象词汇并依据指南组合征象图来诊断和定位未见疾病，在肝脏CT上优于对比方法。
Deep models for radiological diagnosis are typically trained to predict disease labels directly from images, which limits them to diseases seen during training and makes their decisions hard to interpret in radiologists' terms. Radiology, however, proceeds from visual findings to disease through published guidelines that make this decision rule explicit, interpretable, and reproducible. We introduce diagnosis by composition (DbC), a representation learning framework that encodes this findings-first logic. DbC learns a vocabulary of radiological findings by aligning image features with the text embeddings of the findings, each finding represented as a dense map over the scan. A disease is defined by a set of required findings derived from its guidelines, and its diagnosis map is a fixed, parameter-free composition of the corresponding finding maps. Because the finding-to-disease mapping is derived from guidelines rather than learned, DbC is interpretable and auditable by design, can extend to new diseases by specifying their findings without retraining, and can diagnose unseen diseases by composing their findings. On multi-phase liver CT, DbC detects and localizes unseen diseases, rare diseases from a different institution, and an external cohort significantly better than all comparators, including models that align images with disease names. DbC also improves detection and localization in the fully supervised setting and remains superior across training-set sizes. Although demonstrated on liver CT, DbC applies wherever radiological guidelines define diseases through findings.
Experimental design is critical for evidence-based decision-making in healthcare, marketing, and public policy. However, designing efficient experiments across heterogeneous subgroups presents significant challenges. Existing methods often optimize for statistical power or overall sample efficiency, overlooking crucial fairness considerations across these different subgroups. To address this gap, we introduce a Fairness-Aware Contextual Track-and-Stop Design (F-CTSD) algorithm. The proposed F-CTSD algorithm provides statistical guarantees on subgroup fairness while minimizing required sample sizes. We quantify the fairness-efficiency trade-off and derive the exact sample complexity for the proposed F-CTSD algorithm under its fairness constraints. We further theoretically prove that the proposed F-CTSD algorithm consistently produces accurate treatment effect estimates even under fairness requirements, enhancing statistical reliability. Numerical experiments show that the proposed F-CTSD algorithm outperforms existing methods, achieving higher sample efficiency while reducing subgroup fairness violations by 4.95%.
Jung-Hoon Cho, Heling Zhang, Siqi Du, Roy Dong, Cathy Wu
Generalization is crucial for modern control, but learning across tasks can be costly. Recent work shows that zero-shot transfer, in which a controller designed for a source task is directly deployed to a target task, can achieve strong performance. We formalize task-space complexity, which characterizes the difficulty of achieving sufficiently good performance across a collection of tasks, by casting source selection as a covering problem. We provide bounds on the complexity and demonstrate its applicability.
Yumeng Fu Xi'an Jiaotong University, Jiayin Zhu Xi'an Jiaotong University, Lingling Zhang Xi'an Jiaotong University, Wenjun Wu Xi'an Jiaotong University, Bo Zhao Xi'an Jiaotong University, Shaoxuan Ma, Yushun Zhang, Jun Liu Xi'an Jiaotong University
Geometry problem solving (GPS) poses significant challenges for Multimodal Large Language Models (MLLMs) in diagram comprehension, knowledge application, long-step reasoning, and auxiliary line construction. However, current benchmarks lack fine-grained evaluation for long-step problems necessitating auxiliary construction. To address these limitations, we present GeoLaux, a fine-grained annotated dataset comprising 2186 calculation and proof problems. It features long-step reasoning (with an average solution length of 6.51 steps, maximum of 24 steps) and auxiliary line construction (required in 41.8% of problems). Building on the dataset, we conduct a comprehensive five-dimensional evaluation of 23 leading MLLMs. The evaluation yields three pivotal findings: First, models perform significantly worse on long-step problems compared to short-step ones, with 18 models exhibiting a performance drop of over 50%. Second, it is crucial to enhance models’ understanding, awareness, and proficiency in auxiliary line construction, which is vital for overall geometric reasoning. Third, limited answer hints effectively improve process correctness, whereas explicit answers lead models to neglect intermediate reasoning steps. These findings position GeoLaux both to benchmark MLLMs geometry reasoning abilities and to guide their improvement. Data and code are available at https://github.com/Candice-yu/GeoLaux
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Yifei Li, Weidong Guo Tencent, Lingling Zhang Xi'an Jiaotong University, Rongman Xu School of Computer Science and Technology and School of Mathmatics and Statistics, Muye Huang Xi'an Jiaotong University, Hui Liu QQ Browser Lab, Tecent, Lijiao Xu, Yu Xu Tencent 等 9 位作者
Long-term conversational memory is a core capability for LLM-baseddialogue systems, yet existing benchmarks and evaluation protocolsprimarily focus on surface-level factual recall.In realistic interactions, appropriate responses often depend onimplicit constraints such as user state, goals, or values that are notexplicitly queried later.To evaluate this setting, we introduce LoCoMo-Plus, a benchmarkfor assessing cognitive memory under cue–trigger semantic disconnect,where models must retain and apply latent constraints across longconversational contexts.We further show that conventional string-matching metrics and explicittask-type prompting are misaligned with such scenarios, and propose aunified evaluation framework based on constraint consistency.Experiments across diverse backbone models, retrieval-based methods, andmemory systems demonstrate that cognitive memory remains challenging andreveals failures not captured by existing benchmarks.Our code and evaluation framework are publicly available at https://github.com/xjtuleeyf/Locomo-Plus.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Honghao Fu The University of Queensland, Miao Xu The University of Queensland and RIKEN, Yiwei Wang University of California, Merced, Dailing Zhang Institute of automation, Chinese academy of science, Chinese Academy of Sciences, Jun Liu Lancaster University, Yujun Cai The University of Queensland
Scaling multimodal large language models (MLLMs) to long videos is constrained by limited context windows. While retrieval-augmented generation (RAG) is a promising remedy by organizing query-relevant visual evidence into a compact context, most existing methods (i) flatten videos into independent segments, breaking their inherent spatio-temporal structure, and (ii) depend on explicit semantic matching, which can miss cues that are implicitly relevant to the query’s intent. To overcome these limitations, we propose VideoStir, a structured and intent-aware long-video RAG framework. It firstly structures a video as a spatio-temporal graph at clip level, and then performs multi-hop retrieval to aggregate evidence across distant yet contextually related events. Furthermore, it introduces an MLLM-backed intent-relevance scorer that retrieves frames based on their alignment with the query’s reasoning intent. To support this capability, we curate IR-600K, a large-scale dataset tailored for learning frame–query intent alignment. Experiments show that VideoStir is competitive with state-of-the-art baselines without relying on auxiliary information, highlighting the promise of shifting long-video RAG from flattened semantic matching to structured, intent-aware reasoning. Codes and checkpoints are available at https://github.com/RomGai/VideoStir.
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cs.CL · cs.CV
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Ruifeng Yuan, Wanxing Chang, Weiwei Cao Alibaba Group, Bowen Shi Shanghai Jiao Tong University and Alibaba DAMO Academy, Alibaba Group, Zhongyu Wei Fudan University, Ling Zhang Alibaba Group, Jianpeng Zhang
The evaluation of generated reports remains a critical challenge in Computed Tomography (CT) report generation, due to the large volume of text, the diversity and complexity of findings, and the presence of fine-grained, disease-oriented attributes. Conventional evaluation metrics offer only coarse measures of lexical overlap or entity matching and fail to reflect the granular diagnostic accuracy required for clinical use. To address this gap, we propose CT-FineBench, a benchmark built from CT-RATE and Merlin to evaluate the fine-grained factual consistency of CT reports, constructed from CT-RATE and Merlin. Our benchmark is constructed through a meticulous, Question-Answering (QA) based process: first, we identify and structure key, finding-specific clinical attributes (e.g., location, size, margin). Second, we systematically transform these attributes into a QA dataset, where questions probe for specific clinical details grounded in gold-standard reports. The evaluation protocol for CT-FineBench involves using this QA dataset to query a machine-generated report and scoring the correctness of the answers. This allows for a comprehensive, interpretable, and clinically-relevant assessment, moving beyond superficial lexical overlap to pinpoint specific clinical errors. Experiments show that CT-FineBench correlates better with expert clinical assessment and is substantially more sensitive to fine-grained factual errors than prior metrics.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表
Xinyu Zhang Xi'an Jiaotong University, Yuchen Wan, Boxuan Zhang, Zesheng Yang, Lingling Zhang Xi'an Jiaotong University, Bifan Wei Xi'an Jiaotong University, Jun Liu Xi'an Jiaotong University
Large Language Models (LLMs) often struggle with structural ambiguity in optimization problems, where a single problem admits multiple related but conflicting modeling paradigms, hindering effective solution generation. To address this, we propose Dual-Cluster Memory Agent (DCM-Agent) to enhance performance by leveraging historical solutions in a training-free manner. Central to this is Dual-Cluster Memory Construction. This agent assigns historical solutions to modeling and coding clusters, then distills each cluster’s content into three structured types: Approach, Checklist, and Pitfall. This process derives generalizable guidance knowledge. Furthermore, this agent introduces Memory-augmented Inference to dynamically navigate solution paths, detect and repair errors, and adaptively switch reasoning paths with structured knowledge. The experiments across seven optimization benchmarks demonstrate that DCM-Agent achieves an average performance improvement of 11%- 21%. Notably, our analysis reveals a “knowledge inheritance” phenomenon: memory constructed by larger models can guide smaller models toward superior performance, highlighting the framework’s scalability and efficiency.
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cs.CL
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表