论文库

Understanding 4D scenes is a core challenge in visual intelligence, requiring models to jointly capture scene geometry, appearance, and dynamics from partial observations. However, existing approaches are subdivided into feedforward models for direct geometric prediction, and generative models for visual synthesis. We introduce UGG, a unified framework for 4D scene understanding that jointly models RGB video and geometric representations such as depth and camera pose. By assigning different noise levels across modalities and time, UGG formulates visual generation and geometric prediction as conditional completion within a single generative model. This flexible formulation enables the model to learn from diverse, heterogeneous datasets with different subsets of geometric and visual annotations. Furthermore, our generative formulation enables inference-time search over multiple plausible scene hypotheses, using geometric evidence extracted from observed RGB frames to improve geometric prediction without ground truth geometry. We demonstrate UGG's effectiveness over non-unified baselines across camera-controlled video generation, depth estimation, and camera pose prediction, including in challenging sparse observation settings. Code and visualizations are available at https://ugg-model.github.io/

Fetal brain biometry provides a quantitative basis for assessing prenatal growth and identifying congenital brain abnormalities. However, comprehensive assessment remains limited by labor-intensive manual measurements and automated models that lose accuracy across imaging sequences and institutions. We introduce BioTTA, an anatomically guided test-time adaptation framework that measures 11 fetal brain biometrics from reconstructed three-dimensional magnetic resonance images. BioTTA adapts pretrained models to individual unlabeled volumes using geometric consistency and atlas priors, without access to source images. In a retrospective study across five centers in China and Switzerland, BioTTA improved measurement accuracy across three out-of-distribution datasets and two network architectures. It reduced mean absolute measurement errors by 46-82% relative to the corresponding models without adaptation, achieving errors similar to those of supervised fine-tuning. Its measurements were mapped onto normative growth trajectories derived from expert annotations, enabling gestational-age-specific assessment through a web-based reporting platform. Across four disease cohorts, the platform achieved 82.1-95.0% accuracy in binary detection of ventriculomegaly or cerebellar abnormalities, with performance similar to that of a senior radiologist. BioTTA provides a practical foundation for standardized fetal brain biometry across heterogeneous imaging settings, supporting scalable prenatal growth assessment and quantitative evaluation of brain abnormalities.

Objective: Survival analysis is central to medical prediction, yet large language models (LLMs) are rarely used as end-to-end survival models because censoring prevents straightforward supervised fine-tuning. Here we present LLMSurvival, a framework that enables censoring-aware survival analysis with unmodified LLMs operating directly on tabular clinical data. Materials and Methods: LLMSurvival reformulates time-to-event prediction as pairwise ranking among comparable subjects, and derives test-time risk by aggregating comparisons against anchor individuals from the training cohort. Results: Across two clinical tasks (ICU mortality prediction in MIMIC-IV and fragility fracture prediction in a NewYork-Presbyterian/Weill Cornell Medicine cohort), LLMSurvival improves overall concordance over Cox proportional hazards modeling by 3.1% for ICU mortality and 0.5% for fracture risk, 2.1% on average for ICU mortality and 2.8% for fracture risk over three established deep learning survival models. Discussion: The results show that survival modeling with censoring can be made compatible with LLM fine-tuning through comparison-based reformulation. The framework demonstrates high portability and superior performance over expert curated scores like SAPS-II and FRAX scores across diverse clinical context. Furthermore, the framework supports local deployment, as compact, publicly available base models provide sufficient performance. Conclusion: The LLMSurvival framework serves as a proof of concept for an integrated, censoring-conscious approach to survival analysis via LLMs.

Large language model agents are increasingly deployed as multi-agent systems rather than as a standalone model operating within a single context. Recent agent harnesses allow the model to instantiate worker agents and to author the executable workflow that coordinates them, shifting the design of system structure from developers to the model at run time. The quality of this organization therefore constitutes a distinct capability, yet existing benchmarks either measure end-to-end task completion or evaluate coordination under structures specified in advance. We formalize this capability as workflow orchestration and introduce WorkflowArena, a benchmark of 145 long-horizon tasks spanning 8 professional domains, from software engineering and formal mathematics to legal analysis and 3D production. Each task specifies an initial workspace and an integrated deliverable composed of interdependent components, which is assessed by a hidden verifier. Agents determine autonomously whether and how to delegate, and all delegation is recorded, enabling joint evaluation of deliverable quality and the organization of the underlying work. Experiments with nine models show that no single configuration performs best across all domains and that systems exhibit distinct delegation strategies: at high effort, Claude models in Claude Code invoke workflows less frequently but with larger worker groups, whereas GPT models in Codex delegate more frequently in smaller units. When the executing model is held fixed on a challenging subset of tasks, workflows authored by Claude Opus 5.5 substantially improve weaker executors, indicating that workflow organization is itself a measurable determinant of task performance.