← 研踪 PaperTrailarXiv:2611.14013 · v1
A Stage-Wise Explainable Pipeline for Arteriolar-to-Venular Ratio Estimation and Retinopathy Screening
首次提交 2026-11-10 20:51
版本更新 2026-11-10 20:51
雷达观测 2026-11-11 11:04
摘要
The arteriolar-to-venular diameter ratio (AVR) is a clinically motivated marker of retinal vascular health. We present a five-stage pipeline for AVR estimation and exploratory retinopathy screening from fundus images, with inspectable intermediate outputs at each stage. The pipeline combines vessel and artery-vein masks, optic-disc localization, vessel-calibre estimation using a minimal-chord boundary walk, and AVR computation from dominant arterial and venular branches. An explicit threshold-based rule produces the screening decision, enabling errors to be traced to individual processing stages. On an exploratory cohort of 30 HRF images, we report 96.7% accuracy, an F1-score of 0.968 and ROC-AUC of 0.978. Ablation studies and an exploratory comparison with VascX examine the effects of vessel pairing, calibre measurement and aggregation. Interpretation is limited by the small cohort, proxy disease labels and absence of independent reference calibre measurements. The pipeline provides a transparent framework for investigating retinal vascular biomarkers, with further validation needed on larger, clinically graded cohorts.
作者备注：Accepted for presentation at the 23rd IEEE India Council International Conference (INDICON 2026)
观测到的版本
相邻记录可能跳过中间版本；首次发现 v2 及以上也会标为版本更新。
v1 · 2026-11-10 20:51 · 最新观测版本
A Stage-Wise Explainable Pipeline for Arteriolar-to-Venular Ratio Estimation and Retinopathy Screening
The arteriolar-to-venular diameter ratio (AVR) is a clinically motivated marker of retinal vascular health. We present a five-stage pipeline for AVR estimation and exploratory retinopathy screening from fundus images, with inspectable intermediate outputs at each stage. The pipeline combines vessel and artery-vein masks, optic-disc localization, vessel-calibre estimation using a minimal-chord boundary walk, and AVR computation from dominant arterial and venular branches. An explicit threshold-based rule produces the screening decision, enabling errors to be traced to individual processing stages. On an exploratory cohort of 30 HRF images, we report 96.7% accuracy, an F1-score of 0.968 and ROC-AUC of 0.978. Ablation studies and an exploratory comparison with VascX examine the effects of vessel pairing, calibre measurement and aggregation. Interpretation is limited by the small cohort, proxy disease labels and absence of independent reference calibre measurements. The pipeline provides a transparent framework for investigating retinal vascular biomarkers, with further validation needed on larger, clinically graded cohorts.
查看此版本解读 →查看此版本原文 ↗