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新论文 · v1arXiv:2611.12139

BioMARS 2.0: a robotic biologist for formulating and adapting biological experiments

Yibo Qiu, Zan Huang, Yilin Qiao, Ziyang Ling, Yi Wang, Zhengyang Lu, Hangke Peng, Haoliang Ye 等 22 位作者

原文摘要

Biological experimentation is not reducible to a single optimization problem, but requires decisions at multiple levels of abstraction: translating scientific knowledge into experimental procedures, adapting culture conditions to measured phenotypes and selecting interventions that test biological hypotheses. Automating experimental execution does not, by itself, determine which experiments should be performed next or how they should change in response to biological feedback. Here we introduce BioMARS, a human-in-the-loop multi-agent robotic system that connects knowledge-guided experimental decision-making with robotic execution and biological feedback. At the procedural level, BioMARS generated literature-grounded protocols and traceable action plans, improving expert-reviewed protocol quality scores across four model backends. At the parametric level, BioMARS used image-derived phenotypes from robotic retinal organoid culture to select subsequent experimental conditions, with higher reported scores in later rounds of the three-round experiment. At the intervention level, BioMARS nominated drug-repurposing candidates from biomedical evidence and advanced six candidates to wet-lab testing by researchers. Together, these studies demonstrate feedback-driven robotic biological experimentation within a framework that supports decisions about experimental procedures, culture conditions and biological interventions.

cs.RO · q-bio.QM

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arXiv ↗PDF ↗
版本更新 · v2arXiv:2611.00887

Multi-quadrotor systems interconnected via structurally unknown forces and moments

Kaiyue Xing, Shivansh Pratap Singh, Sarthak Mishra, Di Liu, Spandan Roy, Simone Baldi, Leonid Fridman

原文摘要

This work addresses the challenge of controlling multi-quadrotor systems subject to tight uncertain couplings. We consider interconnection forces and moments among the quadrotors to be state-dependent functions of the coordination errors, without assuming knowledge of their functional/parametric structures, e.g., no linear-in-parameters assumptions are made. We only rely on general state-dependent quadratic bounds valid for several Euler-Lagrange mechanical systems. We propose a coordination strategy embedding adaptive laws dedicated to compensating for the lack of structural knowledge. Unlike conventional decoupled position-attitude designs, we present a coupled stability analysis accounting for the position-attitude couplings induced by the interconnection forces and moments. The analysis, along with real experiments involving cooperative aerial transportation of rope-interconnected payloads, demonstrates the effectiveness of the proposed solution in compensating for these complex interconnections. Comparative experiments show that, when a payload drop induces a disturbance propagating through the ropes across the whole formation, the proposed strategy reduces significantly post-disturbance transients.

cs.RO

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arXiv ↗PDF ↗
新论文 · v1arXiv:2611.11258

Auto-GlaKG: Automated Biomarker Reasoning for Explainable Glaucoma Detection

Cheng Huang, Zeyu Han, Yian Hu, Yaopeng Ding, Jingxi Qiu, Yadi Liu

原文摘要

Interpretable glaucoma detection requires a transparent connection between fundus images, clinically meaningful biomarkers, and diagnostic predictions. Knowledge graph (KG) reasoning provides this structure, but performance measured using annotated biomarkers does not establish performance when only images are available. We present Auto-GlaKG, an automated framework that combines image-based biomarker prediction with fixed clinical-prior rules. A ResNet50 network predicts the cup-to-disc ratio (CDR) and six morphological signs using biomarker supervision, and a KG reasoner aggregates their signed rule contributions into a glaucoma score. On 689 fundus images evaluated using stratified, group-aware five-fold cross-validation, Auto-GlaKG achieves a pooled area under the receiver operating characteristic curve (AUC) of 0.951 (95\% confidence interval: 0.931--0.969), with sensitivity of 0.970 and specificity of 0.779. The matched image classifier also achieves an AUC of 0.951, while the rule stage adds 0.2~ms per image. Replacing predicted CDR with its annotation increases fold-mean AUC from 0.953 to 0.995. The framework provides an explicit rule-level account of image-based predictions and identifies CDR estimation as a priority for validation using independently measured biomarkers.

cs.CV · cs.AI

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arXiv ↗PDF ↗
首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-demo.35ACL Anthology · ACL 2026

MASFactory: A Graph-centric Framework for Orchestrating LLM-Based Multi-Agent Systems with Vibe Graphing

Yang Liu, Jinxuan Cai, Yishen Li, Qi Meng Beijing University of Posts and Telecommunications, Zedi Liu, Xin Li Free Org., Chen Qian Shanghai Jiaotong University, Chuan Shi Beijing University of Post and Telecommunication 等 9 位作者

原文摘要

Large language model-based (LLM-based) multi-agent systems (MAS) are increasingly used to extend agentic problem solving via role specialization and collaboration. MAS workflows can be naturally modeled as directed computation graphs, where nodes execute agents or sub-workflows and edges encode dependencies and message passing. However, implementing complex graph workflows in current frameworks still requires substantial manual effort, offers limited reuse, and makes it difficult to integrate heterogeneous external context sources. To overcome these limitations, we present MASFactory, a graph-centric framework for orchestrating LLM-based MAS. It introduces Vibe Graphing, a human-in-the-loop approach that compiles natural-language intent into an editable workflow specification and then into an executable graph. In addition, the framework provides reusable components, skill support, multimodal message handling, and pluggable context integration, as well as a visualizer for topology preview, runtime tracing, and human-in-the-loop interaction. We evaluate MASFactory on seven public benchmarks, validating both reproduction consistency for representative MAS methods and the effectiveness of Vibe Graphing. Our code (https://github.com/BUPT-GAMMA/MASFactory, licensed under Apache-2.0) and video demonstration (https://youtu.be/ANynzVfY32k) are publicly available.

cs.CL · cs.AI · cs.MA · cs.CV

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 3: System Demonstrations) · 2026 · 正式发表

首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.1318ACL Anthology · ACL 2026

DVI-DTM: Dual-View Representation Learning for Interpretable Short Text Dynamic Topic Modeling

Di Liu Beijing University of Posts and Telecommunications, Zheng Fang University of the Chinese Academy of Sciences, Bin Wu Beijing University of Posts and Telecommunications

原文摘要

Dynamic topic modeling aims to capture topic evolution from temporal text corpora. However, existing methods face two major challenges when applied to short texts: semantic ambiguity and interpretation ambiguity. Semantic ambiguity arises from the sparsity of short texts and the neglect of temporal semantic shifts. Interpretation ambiguity refers to the latent topics that lack human-understandable descriptions. In this work, we propose a novel Dual-View representation learning-based Interpretable short text Dynamic Topic Model (DVI-DTM). To address semantic ambiguity, the Dual-View Representation Learning module is presented to learn robust document-topic distributions by aligning temporal-aware term view and sentence view representations of short texts. To tackle interpretation ambiguity, we introduce a GEA Topic Refiner that leverages LLM agents to generate topic descriptions and refine document-topic distributions through collaborative semantic reasoning. Furthermore, a Dual-Factor Ranking module is designed to capture the topic evolution through semantic relevance and temporal uniqueness. Comprehensive experiments demonstrate that DVI-DTM outperforms the state-of-the-art baselines in topic alignment and dynamic topic quality metrics while producing highly interpretable topic descriptions.

cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表

首次观测 · 记录 #1ACL Anthology · ACL 2026:acl:2026.acl-long.357ACL Anthology · ACL 2026

Enhancing the Transferability of Jailbreak Attacks on Large Language Models via Exploiting Reparameterization Invariance

Ao Wang China University of Petroleum (East China), Xinghao Yang, Yongshun Gong Shandong University, Wei Liu University of Technology Sydney, Bao-di Liu, Weifeng Liu China University of Petroleum (East China)

原文摘要

Jailbreak attacks serve as a pivotal technique for evaluating the safety alignment of Large language models. Current token-level attacks have shown remarkable efficacy on open-source models by leveraging gradient-based optimization. However, these attacks suffer from poor cross-model transferability, severely limiting their utility on proprietary ones. To address this limitation, we propose Reparameterization Invariance Gradient-based Jailbreak (RIGJ), a natural gradient based framework designed to improve cross-model transferability. Unlike prior token-level methods whose optimization paths are constrained by model-specific Euclidean geometry, RIGJ defines update directions according to differences in output distributions rather than parameter-space distances. Since language models are trained to capture similar dependency structures of natural language, their output distributions share common geometry across architectures, yielding intrinsically model-agnostic optimization trajectories and substantially stronger jailbreak transferability. Extensive experiments demonstrate superior performance, increasing the cross-model Attack Success Rate and Average Harmfulness Score by 14.9 and 1.23, respectively. Our code is provided https://github.com/nohuma/AISafety_transfer_jailbreak_RIGJ_2026.

cs.CL

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · 2026 · 正式发表