Nuclei instance segmentation is fundamental to quantitative pathology. Yet high-accuracy methods mostly build on large vision transformers (ViTs) or heavy convolutional backbones, whose parameter count and compute cost hinder deployment in clinical and edge settings. We present NucShare, a lightweight model whose shared decoder handles nuclear pixel segmentation, horizontal-vertical distance, and classification through learnable transposed convolutions for upsampling and three lightweight heads, using 37% of independent decoders' parameters with no loss in accuracy. Output-level distillation then transfers knowledge from NucShare-T (UNI2-h) to NucShare-S (ConvNeXt V2-Tiny), reducing 690.5M parameters to 34.7M. On PanNuke they reach mPQ 0.524 and 0.519, above the prior best CFR-SAM-H at 0.511, and NucShare-S surpasses HoVer-Net and Mask R-CNN by 5.6 and 15.0 points; on zero-shot MoNuSeg it attains bPQ 0.668 against CFR-SAM-H's 0.662. Code: https://github.com/L-iMeng-L/Newidea
Progress toward artificial general intelligence (AGI) has largely relied on scaling a resource-intensive executive, System-2, through larger models, more data and compute, longer reasoning, and more agents. We ask whether the next stage may come instead from co-designing it with System-1, a lightweight, semantically aware predictor that evaluates candidate interactions before execution, so that System-2 acts only on those worth their cost. Our answer is a qualified yes. We study \textit{conditional interaction}, a predict--gate--execute--update loop: System-1 estimates each candidate's utility, System-2 executes those admitted by an adaptive threshold, and the outcomes update System-1. The loop spans training, test-time reasoning, adaptive decision-making, and agentic tool use, with utility and cost defined by the application. Under ideal screening and equal execution costs, execution compute falls by a factor approaching $1/ρ_u$, where $ρ_u$ is the density of utility-relevant interactions (cost-weighted when costs differ); prediction errors, exploration, and distribution shift reduce the saving. We bound selection regret by predictor error and the utility margin. These results motivate our central hypothesis: $ρ_u$ is a measurable coordinate of scaling efficiency and makes informative compute a better description of scaling than total compute.